scholarly journals The effects of thermal softening of double-lumen endobronchial tubes on postoperative sore throat, hoarseness and vocal cord injuries: a prospective double-blind randomized trial

2016 ◽  
Vol 116 (2) ◽  
pp. 282-288 ◽  
Author(s):  
J-H. Seo ◽  
C.W. Cho ◽  
D.M. Hong ◽  
Y. Jeon ◽  
J.-H. Bahk
Keyword(s):  
Randomized Trial ◽  
Vocal Cord ◽  
Sore Throat ◽  
Thermal Softening ◽  
Postoperative Sore Throat ◽  
Double Lumen ◽  
Double Blind

scholarly journals Comparison of prophylactic effect of topical Alchemilla vulgaris in glycerine versus that of dexamethasone on postoperative sore throat after tracheal intubation using a double-lumen endobronchial tube: a randomized controlled study

2021 ◽  
Author(s):  
Chan Jong Chung ◽  
Seong Yeop Jeong ◽  
Joon Ho Jeong ◽  
Sung Wan Kim ◽  
Kyung Hyun Lee ◽  
...  
Keyword(s):  
Tracheal Intubation ◽  
Sore Throat ◽  
Normal Saline ◽  
Rating Scale ◽  
Double Lumen Tube ◽  
Controlled Study ◽  
Postoperative Sore Throat ◽  
Double Lumen ◽  
Double Blind ◽  
Oropharyngeal Cavity

Background: Sore throat and hoarseness frequently occur following general anesthesia with tracheal intubation and are effectively reduced when dexamethasone is used prophylactically. Alchemilla vulgaris in glycerine (Neo Mucosal Activator®) suppresses inflammatory response, possibly relieving sore throat.Methods: We enrolled 94 patients (age ≥ 18 years) scheduled for thoracic surgery using double-lumen tube intubation. Before intubation, 0.2 mg/kg of dexamethasone was administered intravenously and 2 ml of normal saline was sprayed into the oropharyngeal cavity (Group D; n = 45), or 0.04 ml/kg normal saline was administered intravenously and 1 g of Neo Mucosal Activator® mixed with 1 ml of normal saline was sprayed into the oropharyngeal cavity (Group N; n = 43), in a double blind and prospectively randomized manner. Postoperative sore throat and hoarseness were recorded using a numeral rating scale and a 4-point scale to detect a change in voice quality following tracheal extubation (at 1, 6, and 24 h). The primary outcome was the incidence of sore throat at 24 h following surgery. The secondary outcomes were incidence and severity of sore throat and hoarseness.Results: There were no significant differences in the incidence of sore throat at 24 h following surgery (57.8% vs. 46.5%; P = 0.290) or in the incidence and intensity of sore throat and hoarseness at 1, 6, and 24 h following surgery between the groups. Conclusions: A. vulgaris in glycerine did not significantly differ from dexamethasone for preventing sore throat and hoarseness owing to intubation.

scholarly journals Efficacy of dexamethasone in reducing the incidence of postoperative sore throat: a double blind randomized study

2018 ◽  
Vol 5 (1) ◽  
pp. 10-15 ◽  
Author(s):  
Sujita Manandhar ◽  
Kishor Manandhar ◽  
Sharad Khakrel
Keyword(s):  
Endotracheal Tube ◽  
Sore Throat ◽  
Randomized Study ◽  
Saline Group ◽  
Controlled Study ◽  
Control Group ◽  
Lower Grade ◽  
Postoperative Sore Throat ◽  
Double Blind ◽  
Dexamethasone Group

Introductions: Postoperative sore throat (POST) is a commonly seen adverse event after general anesthesia with endotracheal intubation. Dexamethasone, a potent corticosteroid with anti-inflammatory action is the most popular steroid studied in this regard with positive results. Methods: This randomized, prospective, double-blinded, placebo-controlled study was conducted on one hundred and ten adult patients of either sex, American Society of Anesthesiologists physical status I & II, undergoing elective surgeries requiring endotracheal tube intubation. After obtaining written informed consent, they were randomly divided into Control (A, n=55) and Dexamethasone (B, n=55) groups and received either an injection of Dexamethasone (Group B) 8 mg intravenously or an equivalent volume of Normal Saline (Group A) just before entering the operating theatre. All the patients received a similar anesthesia with endotracheal tube intubation and at the end of surgery, extubated and transferred to the post-anesthesia care unit. The incidence and severity of sore throat were assessed at 1, 6 and 24 hours post-extubation. Severity of sore throat were graded on a 4 point scale, p <0.05 was considered significant. Results: Incidence of POST in Dexamethasone group was found significantly low compared to the control group up to six hours (p<0.05) but was comparable at 24 hours post extubation. Severity of POST in the study group was of lower grade in compare to control group. Conclusions: Prophylactic intravenous Dexamethasone 8 mg administered to patients undergoing elective surgeries requiring endotracheal tube intubation significantly reduces the incidence and severity of POST up to six hours post-extubation.

Two-handed jaw thrust decreases postoperative sore throat in patients undergoing double-lumen endobronchial intubation

2020 ◽  
Vol 37 (2) ◽  
pp. 105-112
Author(s):  
Jeong J. Park ◽  
Hyub Huh ◽  
Seung Z. Yoon ◽  
Hye-Ja Lim ◽  
Doo Y. Go ◽  
...  
Keyword(s):  
Sore Throat ◽  
Postoperative Sore Throat ◽  
Double Lumen ◽  
Endobronchial Intubation

A Randomized, Double-Blind Comparison of Licorice Versus Sugar-Water Gargle for Prevention of Postoperative Sore Throat and Postextubation Coughing

2013 ◽  
Vol 117 (3) ◽  
pp. 614-621 ◽  
Author(s):  
Kurt Ruetzler ◽  
Michael Fleck ◽  
Sabine Nabecker ◽  
Kristina Pinter ◽  
Gordian Landskron ◽  
...  
Keyword(s):  
Sore Throat ◽  
Postoperative Sore Throat ◽  
Double Blind ◽  
Sugar Water ◽  
Blind Comparison

scholarly journals A Comparative Study of Three Nebulized Medications for the Prevention of Postoperative Sore Throat in the Pediatric Population

2018 ◽  
Vol 12 (1) ◽  
pp. 85-93 ◽  
Author(s):  
Raham Hasan Mostafa ◽  
Ashraf Nabil Saleh ◽  
Mostafa Mansour Hussein
Keyword(s):  
Adverse Effects ◽  
Sore Throat ◽  
Pediatric Population ◽  
Study Data ◽  
P Value ◽  
Double Blind Study ◽  
Postoperative Sore Throat ◽  
Double Blind ◽  
Medication Delivery ◽  
Vital Component

Background: The delivery of aerosolized drugs is a vital component of treatment for many respiratory disorders. We used this mode of medication delivery as a pre-emptive strategy to alleviate a Postoperative Sore Throat (POST) in children receiving general anesthesia. Objectives: The primary aim of the study was to compare the effects of prophylactic ketamine, magnesium sulfate and dexamethasone nebulization, on the intensity of POST. Methods: Through a prospective, randomized, double-blind study, data were collected from children (6-16 years) undergoing surgeries from March 2018 to May 2018. The patients were allocated into 3 equivalent groups (36 patients each). Preoperative nebulization was performed for all patients. Group M received 40 mg/kg magnesium sulphate, group K received 1 mg/kg ketamine, and group D received 0.16 mg dexamethasone. The primary outcome of the study was the incidence and intensity of POST at the 4th postoperative hour. The secondary outcomes included evaluation of adverse effects specifically nausea, vomiting, postoperative cough and postoperative sedation. Results: Patients in the K group had the lowest incidence of POST compared to patients in groups M and D, specifically, at the 4th - postoperative hour (p-value = 0.003). Conclusions: Preoperative nebulization with ketamine was more effective in reducing the intensity of POST in pediatric patients postoperatively without systemic adverse effects.

scholarly journals Comparison of nebulized ketamine and ketamine with clonidine in postoperative sore throat

2017 ◽  
Vol 4 (5) ◽  
pp. 1579 ◽  
Author(s):  
Sunita Jain ◽  
Hari Prasad Bendwal ◽  
Sarita Gohiya ◽  
Neil Alwani ◽  
Santosh Pancholi ◽  
...  
Keyword(s):  
Sore Throat ◽  
Endotracheal Intubation ◽  
Postoperative Morbidity ◽  
Point Scale ◽  
Postoperative Sore Throat ◽  
Hemodynamic Variable ◽  
Double Blind ◽  
Patient Dissatisfaction ◽  
A Minor ◽  
Control Clinical Study

Background: Postoperative sore throat (POST) consider a minor ailment in patients receiving general anesthesia with endotracheal intubation, seen in 21-65% cases but it causes significant distress and increases postoperative morbidity and patient dissatisfaction. This study was done to compare nebulized ketamine and ketamine with clonidine to treat POST.Methods: This was a prospective, randomized, double-blind control clinical study. After approval from institution ethical and scientific committee, study was conducted in between May 2015-April 2016. Written and informed consent was obtained from 100 patients of either sex aged between 20-65 years. ASA I-II, undergoing surgery in supine position lasting up to two hour. Patients were randomized into two groups Group K (n=50) nebulized with 50 mg ketamine (1cc) + 3cc NS =4cc, Group KC (n=50) nebulized with ketamine 50mg (1cc) + clonidine 150µg (1cc) + 2cc NS for 15 min, before general anaesthesia with endotracheal intubation. The POST and hemodynamic variable were monitored before nebulization, after nebulization, before induction, on arrival to PACU and at 4, 8, 12, 24 hours post operatively. POST was graded on 4 point scale (0-3).Results: Overall incidence of POST was 46% (Group K-40%, KC-6%). The Incidence and severity of POST were significantly attenuated in Group KC in comparison to Group K at 4 hours (P= 0.002), 8 hours (P=0.000), 12 hours (P= 0.000) and at 24 hours (P=0.000).Conclusions: Preoperative nebulization with clonidine and ketamine mixture compared to ketamine is more effective in dealing with postoperative sore throat with no adverse effects.

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