scholarly journals EuroSCORE II and N-terminal pro-B-type natriuretic peptide for risk evaluation: an observational longitudinal study in patients undergoing coronary artery bypass graft surgery

2014 ◽  
Vol 113 (1) ◽  
pp. 75-82 ◽  
Author(s):  
J. Holm ◽  
M. Vidlund ◽  
F. Vanky ◽  
Ö. Friberg ◽  
E. Håkanson ◽  
...  
Keyword(s):  
Longitudinal Study ◽  
Coronary Artery ◽  
Coronary Artery Bypass Graft ◽  
Coronary Artery Bypass ◽  
Natriuretic Peptide ◽  
Risk Evaluation ◽  
Artery Bypass ◽  
Bypass Graft ◽  
Artery Bypass Graft

scholarly journals Increased Perioperative B-type Natriuretic Peptide Associates with Heart Failure Hospitalization or Heart Failure Death after Coronary Artery Bypass Graft Surgery

2013 ◽  
Vol 119 (2) ◽  
pp. 284-294 ◽  
Author(s):  
Amanda A. Fox ◽  
Luigino Nascimben ◽  
Simon C. Body ◽  
Charles D. Collard ◽  
Aya A. Mitani ◽  
...  
Keyword(s):  
Heart Failure ◽  
Coronary Artery ◽  
Coronary Artery Bypass Graft ◽  
Coronary Artery Bypass ◽  
Natriuretic Peptide ◽  
Artery Bypass ◽  
Bypass Graft ◽  
Hazard Ratio ◽  
Artery Bypass Graft ◽  
Clinical Model

Abstract Background: Heart failure (HF) is a leading cause of hospitalization and mortality. Plasma B-type natriuretic peptide (BNP) is an established diagnostic and prognostic ambulatory HF biomarker. We hypothesized that increased perioperative BNP independently associates with HF hospitalization or HF death up to 5 yr after coronary artery bypass graft surgery. Methods: The authors conducted a two-institution, prospective, observational study of 1,025 subjects (mean age = 64 ± 10 yr SD) undergoing isolated primary coronary artery bypass graft surgery with cardiopulmonary bypass. Plasma BNP was measured preoperatively and on postoperative days 1–5. The study outcome was hospitalization or death from HF, with HF events confirmed by reviewing hospital and death records. Cox proportional hazards analyses were performed with multivariable adjustments for clinical risk factors. Preoperative and peak postoperative BNP were added to the multivariable clinical model in order to assess additional predictive benefit. Results: One hundred five subjects experienced an HF event (median time to first event = 1.1 yr). Median follow-up for subjects who did not have an HF event = 4.2 yr. When individually added to the multivariable clinical model, higher preoperative and peak postoperative BNP concentrations each, independently associated with the HF outcome (log10 preoperative BNP hazard ratio = 1.93; 95% CI, 1.30–2.88; P = 0.001; log10 peak postoperative BNP hazard ratio = 3.38; 95% CI, 1.45–7.65; P = 0.003). Conclusions: Increased perioperative BNP concentrations independently associate with HF hospitalization or HF death during the 5 yr after primary coronary artery bypass graft surgery. Clinical trials may be warranted to assess whether medical management focused on reducing preoperative and longitudinal postoperative BNP concentrations associates with decreased HF after coronary artery bypass graft surgery.

N-Terminal B-Natriuretic Peptide After Coronary Artery Bypass Graft Surgery

2009 ◽  
Vol 23 (2) ◽  
pp. 147-150 ◽  
Author(s):  
Giuseppe Crescenzi ◽  
Giovanni Landoni ◽  
Elena Bignami ◽  
Ilaria Belloni ◽  
Camilla Biselli ◽  
...  
Keyword(s):  
Coronary Artery ◽  
Coronary Artery Bypass Graft ◽  
Coronary Artery Bypass ◽  
Natriuretic Peptide ◽  
Artery Bypass ◽  
Bypass Graft ◽  
Artery Bypass Graft
Sign in / Sign up

Export Citation Format

Share Document