scholarly journals Sustained effect of spinal cord stimulation on pain and quality of life in painful diabetic peripheral neuropathy

2013 ◽  
Vol 111 (6) ◽  
pp. 1030-1031 ◽  
Author(s):  
R. Slangen ◽  
W.A. Pluijms ◽  
C.G. Faber ◽  
C.D. Dirksen ◽  
A.G.H. Kessels ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Spinal Cord ◽  
Peripheral Neuropathy ◽  
Spinal Cord Stimulation ◽  
Diabetic Peripheral Neuropathy ◽  
Painful Diabetic Peripheral Neuropathy ◽  
Sustained Effect

A Real-World Analysis of High-Frequency 10 kHz Spinal Cord Stimulation for the Treatment of Painful Diabetic Peripheral Neuropathy

2021 ◽  
pp. 193229682110603
Author(s):  
Jeffrey L. Chen ◽  
Andrew W. Hesseltine ◽  
Sara E. Nashi ◽  
Shawn M. Sills ◽  
Tory L. McJunkin ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Peripheral Neuropathy ◽  
Pain Relief ◽  
Diabetic Neuropathy ◽  
Real World ◽  
Spinal Cord Stimulation ◽  
Diabetic Peripheral Neuropathy ◽  
High Frequency ◽  
Clinical Practices ◽  
Painful Diabetic Peripheral Neuropathy

Background: Diabetes is one of the most prevalent chronic health conditions and diabetic neuropathy one of its most prevalent and debilitating complications. While there are treatments available for painful diabetic peripheral neuropathy (pDPN), their effectiveness is limited. Method: This retrospective, multi-center, real-world review assessed pain relief and functional improvements for consecutive patients with diabetic neuropathy aged ≥18 years of age who were permanently implanted with a high-frequency (10 kHz) spinal cord stimulation (SCS) device. Available data were extracted from a commercial database. Results: In total 89 patients consented to being included in the analysis. Sixty-one percent (54/89) of participants were male and the average age was 64.4 years (SD = 9.1). Most patients (78.7%, 70/89) identified pain primarily in their feet or legs bilaterally. At the last assessment, 79.5% (58/73) of patients were treatment responders, defined as having at least 50% patient-reported pain relief from baseline. The average time of follow-up was 21.8 months (range: 4.3 to 46.3 months). A majority of patients reported improvements in sleep and overall function relative to their baseline. Conclusions: This real-world study in typical clinical practices found 10 kHz SCS provided meaningful pain relief for a substantial proportion of patients refractory to current pDPN management, similar to published literature. This patient population has tremendous unmet needs and this study helps demonstrate the potential for 10 kHz SCS to provide an alternative pain management approach.

Treatment of painful diabetic peripheral neuropathy

2015 ◽  
Vol 39 (1) ◽  
pp. 17-28 ◽  
Author(s):  
Casandra J Rosenberg ◽  
James C Watson
Keyword(s):  
Quality Of Life ◽  
Peripheral Neuropathy ◽  
Side Effects ◽  
Diabetic Peripheral Neuropathy ◽  
Pain Control ◽  
Treatment Options ◽  
Mechanisms Of Action ◽  
Treatment Modalities ◽  
Painful Diabetic Peripheral Neuropathy

Background: Painful diabetic peripheral neuropathy impairs quality of life and can be difficult to treat. Objective: To discuss current treatment recommendations for painful diabetic peripheral neuropathy. Study design: Literature review. Methods: Systematic review of the literature discussing treatment of painful diabetic peripheral neuropathy. Existing treatment guidelines were studied and compared. Results: Painful diabetic peripheral neuropathy occurs in about one in six people with diabetes. This condition impairs quality of life and increases healthcare costs. Treatment recommendations exist, but individual patient therapy can require a trial-and-error approach. Many treatment options have adjuvant benefits or side effects which should be considered prior to initiating therapy. Often, a combination of treatment modalities with various mechanisms of action is required for adequate pain control. Adequate medication titration and a reasonable trial period should be allowed. Conclusion: The treatment of painful diabetic peripheral neuropathy can be challenging, but effective management can improve patient’s quality of life. Clinical relevance Painful diabetic peripheral neuropathy impairs quality of life and can be difficult to treat. Many treatment options have adjuvant benefits or side effects which should be considered prior to initiating therapy. Often, a combination of treatment modalities with various mechanisms of action is required for adequate pain control.

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