scholarly journals Oxygen consumption and delivery relationship in brain-dead organ donors

1996 ◽  
Vol 76 (6) ◽  
pp. 783-789 ◽  
Author(s):  
O Langeron ◽  
P Couture ◽  
J Mateo ◽  
B Riou ◽  
J L Pansard ◽  
...  
Keyword(s):  
Oxygen Consumption ◽  
Organ Donors ◽  
Brain Dead ◽  
Oxygen Consumption And Delivery

Alteration in the Transcriptional Profile of Livers from Brain-dead Organ Donors

2006 ◽  
Vol 82 (1) ◽  
pp. 69-79 ◽  
Author(s):  
Gualtiero Colombo ◽  
Stefano Gatti ◽  
Flavia Turcatti ◽  
Caterina Lonati ◽  
Andrea Sordi ◽  
...  
Keyword(s):  
Transcriptional Profile ◽  
Organ Donors ◽  
Brain Dead

326 A Randomized Trial of Nebulized Albuterol To Enhance Resolution of Pulmonary Edema in 506 Brain Dead Organ Donors

2012 ◽  
Vol 31 (4) ◽  
pp. S116 ◽  
Author(s):  
L.B. Ware ◽  
M. Landeck ◽  
T. Koyama ◽  
E. Johnson ◽  
G.R. Bernard ◽  
...  
Keyword(s):  
Pulmonary Edema ◽  
Randomized Trial ◽  
Organ Donors ◽  
Brain Dead

ANENCEPHALIC ORGAN DONORS

PEDIATRICS ◽  
1989 ◽  
Vol 83 (2) ◽  
pp. A42-A42
Author(s):  
Student
Keyword(s):  
Brain Death ◽  
Low Dose ◽  
Organ Donors ◽  
Policy Choices ◽  
Minute Period ◽  
Definite Time ◽  
Periodic Testing ◽  
Basic Protocol ◽  
Brain Dead ◽  
Canadian Group

[There are] two policy choices: we can abandon attempts to justify use of anencephalic infants as organ donors because there is currently no clinically accepted means to declare brain death in these infants; or we can carry out the research necessary to establish a clinically valid procedure for doing so. A Canadian group has decided to take the second route and experiment on methods to use as organ donors anencephalic newborns who can be validly declared brain-dead on classic criteria. The group has developed a basic protocol that calls for the parents to agree, prior to birth, that: (1) the infant will be resuscitated; (2) periodic testing will be done to determine brain death (removal from the ventilator at six-to-twelve-hour intervals for a ten-minute period to determine ability to breathe spontaneously; (3) organ donation is acceptable; and (4) a definite time limit (to be determined by the parents but not more than fourteen days) after which the infant will be removed from the ventilator and permitted to die. Low-dose morphine is administered to prevent potential suffering on the part of the infant, although whether anencephalic newborns can suffer is unknown.

Intraoperative Hemodynamic Heterogeneity of Brain Dead Organ Donors

1992 ◽  
Vol 36 (4) ◽  
pp. 268
Author(s):  
P. E. DUKE ◽  
M. A. E. RAMSAY ◽  
A. W. PAULSEN ◽  
T. C. GUNNING ◽  
L. C. ROBERTS ◽  
...  
Keyword(s):  
Organ Donors ◽  
Brain Dead

Honoring Donor Designation in Brain Dead Organ Donors

2017 ◽  
Vol 101 ◽  
pp. S13
Author(s):  
Susan Larson ◽  
Susan Gunderson ◽  
Sue Weese
Keyword(s):  
Organ Donors ◽  
Brain Dead

Perioperative hemodynamic heterogeneity of brain dead organ donors

1992 ◽  
pp. 719-721
Author(s):  
P. K. Duke ◽  
M. A. B. Ramsay ◽  
T. C. Gunning ◽  
A. W. Paulsen ◽  
L. C. Roberts
Keyword(s):  
Organ Donors ◽  
Brain Dead

scholarly journals Randomised sham-controlled double-blind trial evaluating remote ischaemic preconditioning in solid organ transplantation: a study protocol for the RIPTRANS trial

BMJ Open ◽  
2020 ◽  
Vol 10 (11) ◽  
pp. e038340
Author(s):  
Aki Uutela ◽  
Ilkka Helanterä ◽  
Karl Lemström ◽  
Arie Passov ◽  
Simo Syrjälä ◽  
...  
Keyword(s):  
Organ Transplantation ◽  
Study Protocol ◽  
Solid Organ Transplantation ◽  
Solid Organ ◽  
Organ Donors ◽  
Ischaemic Preconditioning ◽  
Study Results ◽  
Remote Ischaemic Preconditioning ◽  
Brain Dead ◽  
Transplanted Organs

IntroductionRemote ischaemic preconditioning (RIPC) using a non-invasive pneumatic tourniquet is a potential method for reducing ischaemia-reperfusion injury. RIPC has been extensively studied in animal models and cardiac surgery, but scarcely in solid organ transplantation. RIPC could be an inexpensive and simple method to improve function of transplanted organs. Accordingly, we aim to study whether RIPC performed in brain-dead organ donors improves function and longevity of transplanted organs.Methods and analysesRIPTRANS is a multicentre, sham-controlled, parallel group, randomised superiority trial comparing RIPC intervention versus sham-intervention in brain-dead organ donors scheduled to donate at least one kidney. Recipients of the organs (kidney, liver, pancreas, heart, lungs) from a randomised donor will be included provided that they give written informed consent. The RIPC intervention is performed by inflating a thigh tourniquet to 300 mm Hg 4 times for 5 min. The intervention is done two times: first right after the declaration of brain death and second immediately before transferring the donor to the operating theatre. The sham group receives the tourniquet, but it is not inflated. The primary endpoint is delayed graft function (DGF) in kidney allografts. Secondary endpoints include short-term functional outcomes of transplanted organs, rejections and graft survival in various time points up to 20 years. We aim to show that RIPC reduces the incidence of DGF from 25% to 15%. According to this, the sample size is set to 500 kidney transplant recipients.Ethics and disseminationThis study has been approved by Helsinki University Hospital Ethics Committee and Helsinki University Hospital’s Institutional Review Board. The study protocol was be presented at the European Society of Organ Transplantation congress in Copenhagen 14−15 September 2019. The study results will be submitted to an international peer-reviewed scientific journal for publication.Trial registration numberNCT03855722.

Safety of Donation From Brain-dead Organ Donors With Central Nervous System Tumors

2020 ◽  
Vol 104 (3) ◽  
pp. 460-466
Author(s):  
Mi-Sung Lee ◽  
Won-Hyun Cho ◽  
Jongwon Ha ◽  
Eun-Suk Yu ◽  
Young-Soon Jeong ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Central Nervous System Tumors ◽  
Organ Donors ◽  
Nervous System Tumors ◽  
Brain Dead

Endocrine stress reaction to surgery in brain-dead organ donors

1996 ◽  
Vol 9 (2) ◽  
pp. 102-108 ◽  
Author(s):  
R.D. Fitzgerald ◽  
I. Dechtyar ◽  
E. Templ ◽  
T. Pernerstorfer ◽  
W. Hackl ◽  
...  
Keyword(s):  
Stress Reaction ◽  
Organ Donors ◽  
Brain Dead
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