scholarly journals THE EFFECTS OF GENERAL ANAESTHETICS ON CEREBRAL BLOODFLOW AND CEREBRAL METABOLISM

1965 ◽  
Vol 37 (4) ◽  
pp. 236-245 ◽  
Author(s):  
D. GORDON MCDOWALL
Keyword(s):  
Cerebral Metabolism ◽  
Cerebral Bloodflow

2D NMR studies on muscle and cerebral metabolism in vivo

1994 ◽  
Vol 91 ◽  
pp. 697-703 ◽  
Author(s):  
B Gillet ◽  
BT Doan ◽  
C Verre-Sebrie ◽  
O Fedeli ◽  
JC Beloeil ◽  
...  
Keyword(s):  
Cerebral Metabolism ◽  
2D Nmr ◽  
Nmr Studies

scholarly journals Curbing action potential generation or ATP-synthase leads to a decrease in in-cell pyruvate dehydrogenase activity in rat cerebrum slices

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Benjamin Grieb ◽  
Sivaranjan Uppala ◽  
Gal Sapir ◽  
David Shaul ◽  
J. Moshe Gomori ◽  
...  
Keyword(s):  
Action Potential ◽  
Atp Synthase ◽  
Neural Activity ◽  
Pyruvate Dehydrogenase ◽  
Cerebral Metabolism ◽  
Neuronal Firing ◽  
Action Potential Generation ◽  
Potential Generation ◽  
Drastic Increase ◽  
Rat Cerebrum

AbstractDirect and real-time monitoring of cerebral metabolism exploiting the drastic increase in sensitivity of hyperpolarized 13C-labeled metabolites holds the potential to report on neural activity via in-cell metabolic indicators. Here, we followed the metabolic consequences of curbing action potential generation and ATP-synthase in rat cerebrum slices, induced by tetrodotoxin and oligomycin, respectively. The results suggest that pyruvate dehydrogenase (PDH) activity in the cerebrum is 4.4-fold higher when neuronal firing is unperturbed. The PDH activity was 7.4-fold reduced in the presence of oligomycin, and served as a pharmacological control for testing the ability to determine changes to PDH activity in viable cerebrum slices. These findings may open a path towards utilization of PDH activity, observed by magnetic resonance of hyperpolarized 13C-labeled pyruvate, as a reporter of neural activity.

Effects of stroke on local cerebral metabolism and perfusion: Mapping by emission computed tomography of18FDG and13NH3

1980 ◽  
Vol 8 (1) ◽  
pp. 47-60 ◽  
Author(s):  
David E. Kuhl ◽  
Michael E. Phelps ◽  
Arthur P. Kowell ◽  
E. Jeffrey Metter ◽  
Carl Selin ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Cerebral Metabolism ◽  
Emission Computed Tomography ◽  
Emission Computed

scholarly journals Clinical Factors Associated with Cerebral Metabolism in Term Neonates with Congenital Heart Disease

2017 ◽  
Vol 183 ◽  
pp. 67-73.e1 ◽  
Author(s):  
Anna Lonyai Harbison ◽  
Jodie K. Votava-Smith ◽  
Sylvia del Castillo ◽  
S. Ram Kumar ◽  
Vince Lee ◽  
...  
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Congenital Heart ◽  
Cerebral Metabolism ◽  
Clinical Factors ◽  
Term Neonates ◽  
Factors Associated

scholarly journals Cerebral Metabolism is Influenced by Muscle Ischaemia During Exercise in Humans

2003 ◽  
Vol 88 (2) ◽  
pp. 297-302 ◽  
Author(s):  
Mads K. Dalsgaard ◽  
Lars Nybo ◽  
Yan Cai ◽  
Niels H. Secher
Keyword(s):  
Cerebral Metabolism ◽  
Muscle Ischaemia ◽  
Exercise In Humans
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