Nonsense in the testis: multiple roles for nonsense-mediated decay revealed in male reproduction

Clinton C. MacDonald; Petar N. Grozdanov

doi:10.1093/biolre/iox033

Nonsense in the testis: multiple roles for nonsense-mediated decay revealed in male reproduction

Biology of Reproduction ◽

10.1093/biolre/iox033 ◽

2017 ◽

Vol 96 (5) ◽

pp. 939-947 ◽

Cited By ~ 8

Author(s):

Clinton C. MacDonald ◽

Petar N. Grozdanov

Keyword(s):

Multiple Roles ◽

Male Reproduction ◽

Nonsense Mediated Decay

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The effect of treatment by L-carnitine for infertile men on semen parameters

Tikrit Journal of Pure Science ◽

10.25130/j.v24i2.797 ◽

2019 ◽

Vol 24 (2) ◽

pp. 30

Author(s):

Abdul Rahman Jihad Manssor1 ◽

Zaid Mohammed Mubarak Al–Mahdawi1 ◽

Azzawi Mustafa Hadi2

Keyword(s):

Male Infertility ◽

Semen Quality ◽

Antioxidant Properties ◽

Sperm Concentration ◽

Multiple Roles ◽

Male Reproduction ◽

Semen Parameters ◽

Beneficial Effects ◽

Sperm Counts ◽

Effect Of Treatment

L-Carnitine (LC) is highly concentrated in the epididymis and plays a crucial role in sperm metabolism and maturation. They are related to sperm motility and have antioxidant properties. The objective of this review is to summarize the multiple roles played by LC in male reproduction, and to highlight their limitations as well as their benefits in the treatment of male infertility. A variety of studies support the conclusion that LC at total daily amounts of at least 500mg per day can significantly improve both sperm concentration and total sperm counts among men with astheno – or oligoasthenozoospermia. Although many clinical trials have demonstrated the beneficial effects of LC in selected cases of male infertility. Additional, a well – designed study is necessary to further validate the use of carnitines in the treatment of patients with male infertility, specifically in men with poor semen quality . http://dx.doi.org/10.25130/tjps.24.2019.027

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Microchemistry of ZnO Varistors

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100133102 ◽

1992 ◽

Vol 50 (2) ◽

pp. 1694-1695

Author(s):

K. K. Soni ◽

J. Hwang ◽

V. P. Dravid ◽

T. O. Mason ◽

R. Levi-Setti

Keyword(s):

Grain Boundaries ◽

Multiple Roles ◽

Grain Boundary Engineering ◽

Ion Microprobe ◽

Dopant Distribution ◽

Important Ingredient ◽

Zno Varistor ◽

Zno Varistors ◽

Zno Powder ◽

The University

ZnO varistors are made by mixing semiconducting ZnO powder with powders of other metal oxides e.g. Bi2O3, Sb2O3, CoO, MnO2, NiO, Cr2O3, SiO2 etc., followed by conventional pressing and sintering. The non-linear I-V characteristics of ZnO varistors result from the unique properties that the grain boundaries acquire as a result of dopant distribution. Each dopant plays important and sometimes multiple roles in improving the properties. However, the chemical nature of interfaces in this material is formidable mainly because often trace amounts of dopants are involved. A knowledge of the interface microchemistry is an essential component in the ‘grain boundary engineering’ of materials. The most important ingredient in this varistor is Bi2O3 which envelopes the ZnO grains and imparts high resistance to the grain boundaries. The solubility of Bi in ZnO is very small but has not been experimentally determined as a function of temperature.In this study, the dopant distribution in a commercial ZnO varistor was characterized by a scanning ion microprobe (SIM) developed at The University of Chicago (UC) which offers adequate sensitivity and spatial resolution.

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