scholarly journals Alternative polyadenylation sites reveal distinct chromatin accessibility and histone modification in human cell lines

2013 ◽  
Vol 29 (14) ◽  
pp. 1713-1717 ◽  
Author(s):  
C.-y. Lee ◽  
L. Chen
Keyword(s):  
Histone Modification ◽  
Cell Lines ◽  
Human Cell ◽  
Alternative Polyadenylation ◽  
Chromatin Accessibility ◽  
Human Cell Lines ◽  
Polyadenylation Sites

scholarly journals Simultaneous profiling of chromatin accessibility and methylation on human cell lines with nanopore sequencing

2020 ◽  
Vol 17 (12) ◽  
pp. 1191-1199
Author(s):  
Isac Lee ◽  
Roham Razaghi ◽  
Timothy Gilpatrick ◽  
Michael Molnar ◽  
Ariel Gershman ◽  
...  
Keyword(s):  
Cell Lines ◽  
Human Cell ◽  
Chromatin Accessibility ◽  
Nanopore Sequencing ◽  
Human Cell Lines

scholarly journals Simultaneous profiling of chromatin accessibility and methylation on human cell lines with nanopore sequencing

2018 ◽  
Author(s):  
Isac Lee ◽  
Roham Razaghi ◽  
Timothy Gilpatrick ◽  
Michael Molnar ◽  
Norah Sadowski ◽  
...  
Keyword(s):  
Cell Lines ◽  
Human Cell ◽  
Large Scale ◽  
Human Cancer ◽  
Chromatin Accessibility ◽  
Nanopore Sequencing ◽  
Human Cell Lines ◽  
Sequencing Data ◽  
Structural Variations ◽  
Genetic Changes

ABSTRACTUnderstanding how the genome and the epigenome work together to control gene transcription has applications in our understanding of diseases such as human cancer. In this study, we combine the ability of NOMe-seq to simultaneously evaluate CpG methylation and chromatin accessibility, with long-read nanopore sequencing technology, a method we call nanoNOMe. We generated >60Gb whole-genome nanopore sequencing data for each of four human cell lines (GM12878, MCF-10A, MCF-7, MDA-MB-231) including repetitive regions inaccessible by short read sequencing. Using the long reads, we find that we can observe phased methylation and chromatin accessibility, large scale pattern changes, and genetic changes such as structural variations from a single assay.

Investigations of the influence of microgravity on the state of human cell lines

2004 ◽  
Vol 10 (5-6) ◽  
pp. 226-228
Author(s):  
L.M. Nosach ◽  
◽  
O.Yu. Povnitsa ◽  
V.L. Zhovnovata ◽  
◽  
...  
Keyword(s):  
Cell Lines ◽  
Human Cell ◽  
The State ◽  
Human Cell Lines

scholarly journals Dicalcin suppresses in vitro trophoblast attachment in human cell lines

2021 ◽  
Vol 570 ◽  
pp. 206-213
Author(s):  
Ryohei Saito ◽  
Hiromasa Satoh ◽  
Kayo Aoba ◽  
Hajime Hirasawa ◽  
Naofumi Miwa
Keyword(s):  
Cell Lines ◽  
Human Cell ◽  
Human Cell Lines

scholarly journals Differential Effects of Cyanidin and Cyanidin-3-glucoside on Human Cell Lines

2011 ◽  
Vol 17 (6) ◽  
pp. 515-521 ◽  
Author(s):  
Masayuki TAKEUCHI ◽  
Katsuki OHTANI ◽  
Yanju MA ◽  
Sanae KATO ◽  
Shingo SEMBA ◽  
...  
Keyword(s):  
Cell Lines ◽  
Human Cell ◽  
Human Cell Lines ◽  
Differential Effects
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