scholarly journals A new statistical approach to detecting differentially methylated loci for case control Illumina array methylation data

2012 ◽  
Vol 28 (8) ◽  
pp. 1109-1113 ◽  
Author(s):  
Z. Chen ◽  
Q. Liu ◽  
S. Nadarajah
Keyword(s):  
Statistical Approach ◽  
Case Control ◽  
Methylation Data ◽  
Illumina Array

scholarly journals Conceptual, epidemiological and methodological design aspects for the study of pre-eclampsia

2016 ◽  
pp. 69-69
Author(s):  
María Pía Monteverde ◽  
Shadia Coronel Acosta ◽  
Eddy R Segura
Keyword(s):  
Statistical Approach ◽  
Case Control Study ◽  
Case Control ◽  
Case Control Studies ◽  
Administrative Records ◽  
Relative Risks ◽  
Exposure Variable ◽  
Cohort Study Design ◽  
Study Population ◽  
Control Study

We read with high interest the article by Alzate et al1, and hereby we share comments about its design, study population and statistical approach along with revisiting some key concepts of the disease. The prevalence of preeclampsia in Colombia is 4.5%2 and a case-control study is appropriate to investigate risk and protective factors associated in such setting and their corresponding Odds Ratios. However, in the population studied by Alzate et al, the proportion of preeclampsia is 10% (387/3866 ). Under this scenario, a retrospective cohort study design is also appropriate and allows for direct estimation of incidences and relative risks could also be considered with direct estimates of relative risk. The exposure under study here (calcium prescription) is easy to measure from medical or administrative records or electronic files, therefore its comprehensive assessment in the whole population is feasible, cheap and easy to detect. Case-control studies are usually recommended when these requirements are not met for the exposure variable.

scholarly journals Detecting differentially methylated loci for Illumina Array methylation data based on human ovarian cancer data

2013 ◽  
Vol 6 (S1) ◽  
Author(s):  
Zhongxue Chen ◽  
Hanwen Huang ◽  
Jianzhong Liu ◽  
Hon Keung Tony Ng ◽  
Saralees Nadarajah ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Human Ovarian Cancer ◽  
Methylation Data ◽  
Cancer Data ◽  
Ovarian Cancer Data ◽  
Illumina Array

Precursor lesions of gastric polyps developing during maintenance omeprazole. A case-control study

2001 ◽  
Vol 120 (5) ◽  
pp. A657-A658
Author(s):  
A CATS ◽  
E BLOEMENA ◽  
E SCHENK ◽  
I CLINICS ◽  
S MEUWISSEN ◽  
...  
Keyword(s):  
Case Control Study ◽  
Case Control ◽  
Precursor Lesions ◽  
Gastric Polyps ◽  
Control Study

Risk factors for esophageal adenocarcinoma: A case-control study

2001 ◽  
Vol 120 (5) ◽  
pp. A442-A442
Author(s):  
B AVIDAN ◽  
A SONNENBERG ◽  
T SCHNELL ◽  
G CHEJFEC ◽  
A METZ ◽  
...  
Keyword(s):  
Risk Factors ◽  
Esophageal Adenocarcinoma ◽  
Case Control Study ◽  
Case Control ◽  
Control Study
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