scholarly journals HPID: The Human Protein Interaction Database

2004 ◽  
Vol 20 (15) ◽  
pp. 2466-2470 ◽  
Author(s):  
K. Han ◽  
B. Park ◽  
H. Kim ◽  
J. Hong ◽  
J. Park
Database ◽  
2012 ◽  
Vol 2012 ◽  
Author(s):  
Daniel G. Jamieson ◽  
Martin Gerner ◽  
Farzaneh Sarafraz ◽  
Goran Nenadic ◽  
David L. Robertson

2009 ◽  
Vol 37 (Database) ◽  
pp. D417-D422 ◽  
Author(s):  
W. Fu ◽  
B. E. Sanders-Beer ◽  
K. S. Katz ◽  
D. R. Maglott ◽  
K. D. Pruitt ◽  
...  

2014 ◽  
Vol 10 (10) ◽  
pp. 2713-2723 ◽  
Author(s):  
M. Burnette ◽  
T. Brito-Robinson ◽  
J. Li ◽  
J. Zartman

We describe a novel approach to screen for growth promoting compounds and score putative targets using a drug–protein interaction database.


2020 ◽  
Vol 2020 ◽  
pp. 1-7
Author(s):  
YuHang Zhang ◽  
Tao Zeng ◽  
Lei Chen ◽  
ShiJian Ding ◽  
Tao Huang ◽  
...  

Coronaviruses are specific crown-shaped viruses that were first identified in the 1960s, and three typical examples of the most recent coronavirus disease outbreaks include severe acute respiratory syndrome (SARS), Middle East respiratory syndrome (MERS), and COVID-19. Particularly, COVID-19 is currently causing a worldwide pandemic, threatening the health of human beings globally. The identification of viral pathogenic mechanisms is important for further developing effective drugs and targeted clinical treatment methods. The delayed revelation of viral infectious mechanisms is currently one of the technical obstacles in the prevention and treatment of infectious diseases. In this study, we proposed a random walk model to identify the potential pathological mechanisms of COVID-19 on a virus–human protein interaction network, and we effectively identified a group of proteins that have already been determined to be potentially important for COVID-19 infection and for similar SARS infections, which help further developing drugs and targeted therapeutic methods against COVID-19. Moreover, we constructed a standard computational workflow for predicting the pathological biomarkers and related pharmacological targets of infectious diseases.


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