scholarly journals Experimental advances in the characterization of metazoan gene regulatory networks

2008 ◽  
Vol 8 (1) ◽  
pp. 12-27 ◽  
Author(s):  
B. Deplancke
Keyword(s):  
Gene Regulatory Networks ◽  
Regulatory Networks ◽  
Gene Regulatory

scholarly journals Molecular characterization of gene regulatory networks in primary human tracheal and bronchial epithelial cells

2018 ◽  
Vol 17 (4) ◽  
pp. 444-453 ◽  
Author(s):  
Austin E. Gillen ◽  
Rui Yang ◽  
Calvin U. Cotton ◽  
Aura Perez ◽  
Scott H. Randell ◽  
...  
Keyword(s):  
Epithelial Cells ◽  
Molecular Characterization ◽  
Gene Regulatory Networks ◽  
Regulatory Networks ◽  
Bronchial Epithelial Cells ◽  
Bronchial Epithelial ◽  
Gene Regulatory

scholarly journals Integration of a Computational Pipeline for Dynamic Inference of Gene Regulatory Networks in Single Cells

2019 ◽  
Author(s):  
Kyung Dae Ko ◽  
Stefania Dell’Orso ◽  
Aster H. Juan ◽  
Vittorio Sartorelli
Keyword(s):  
Prior Knowledge ◽  
Gene Regulatory Networks ◽  
Regulatory Networks ◽  
Developmental Stages ◽  
Individual Cell ◽  
Single Cells ◽  
Rna Seq ◽  
Gene Regulatory ◽  
Molecular Expression

SUMMARYSingle-cell RNA-seq permits the characterization of the molecular expression states of individual cells. Several methods have been developed to spatially and temporally resolve individual cell populations. However, these methods are not always integrated and some of them are constrained by prior knowledge. Here, we present an integrated pipeline for inference of gene regulatory networks. The pipeline does not rely on prior knowledge, it improves inference accuracy by integrating signatures from different data dimensions and facilitates tracing variation of gene expression by visualizing gene-interacting patterns of co-expressed gene regulatory networks at distinct developmental stages.

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