scholarly journals A Systematic Review of the Neuropsychological Sequelae of People Diagnosed with Anti N-Methyl-D-Aspartate Receptor Encephalitis in the Acute and Chronic Phases

Author(s):  
Della C M Nicolle ◽  
Jennifer L Moses
2021 ◽  
Vol 429 ◽  
pp. 118811
Author(s):  
Alessandro Dinoto ◽  
Marta Cheli ◽  
Arianna Sartori ◽  
Alessio Bratina ◽  
Paolo Manganotti

2020 ◽  
Vol 64 ◽  
pp. 9-16
Author(s):  
Jordi Serra-Mestres ◽  
Beatriz Villagrasa-Blasco ◽  
Vikram Thacker ◽  
Walter Jaimes-Albornoz ◽  
Puja Sharma ◽  
...  

2017 ◽  
Vol 2017 ◽  
pp. 1-6 ◽  
Author(s):  
Giuseppe Di Iorio ◽  
Gaia Baroni ◽  
Marco Lorusso ◽  
Chiara Montemitro ◽  
Maria Chiara Spano ◽  
...  

Several evidences support the hypothesis that glutamatergic dysfunction may be implicated in the pathogenesis of schizophrenia and in the last few years great interest has been focused on the role of the N-methyl-D-aspartate receptor (NMDAR). Glutamate is the main excitatory neurotransmitter in human CNS and it plays a prominent role in synaptic plasticity, learning, and memory and other cognitive functions. Increasing interest in memantine add-on therapy in schizophrenic patients with negative and cognitive symptoms may suggest that memantine could be a new promising treatment in schizophrenia. The aim of this update was to evaluate clinical data about the memantine effectiveness in schizophrenic patients. Our systematic review of the literature highlights that memantine therapy in schizophrenic patients seems to improve mainly negative symptoms while positive symptoms and cognitive symptoms did not improve significantly.


Author(s):  
N.F. Narvaez Linares ◽  
M. Poitras ◽  
J. Burkauskas ◽  
K. Nagaratnam ◽  
Z. Burr ◽  
...  

2021 ◽  
Vol 11 (3) ◽  
pp. 392
Author(s):  
Pablo Cabezudo-García ◽  
Natalia Mena-Vázquez ◽  
Nicolás L. Ciano-Petersen ◽  
Guillermina García-Martín ◽  
Guillermo Estivill-Torrús ◽  
...  

Background: The prevalence of neural autoantibodies in epilepsy of unknown etiology varies among studies. We aimed to conduct a systematic review and meta-analysis to determine the pooled global prevalence and the prevalence for each antibody. Methods: A systematic search was conducted for studies that included prospectively patients ≥16 years old with epilepsy of unknown etiology and systematically determined neural autoantibodies. A meta-analysis was undertaken to estimate pooled prevalence in total patients with a positive result for at least one neural autoantibody in serum and/or cerebrospinal fluid (CSF) and for each autoantibody. Results: Ten of the eleven studies that met the inclusion criteria and a total of 1302 patients with epilepsy of unknown etiology were included in themeta-analysis. The global pooled prevalence (IC95%) was 7.6% (4.6–11.2) in a total of 82 patients with a positive result for any neural autoantibody. None of the controls available in the studies had a positive result. Individual pooled prevalence for each autoantibody was: glycine receptor (GlyR) (3.2%), glutamic acid decarboxylase (GAD) (1.9%), N-methyl-d-aspartate receptor (NMDAR) (1.8%), leucine-rich glioma inactivated-1 protein (LGI1) (1.1%), contactin-2-associated protein (CASPR2) (0.6%) and onconeuronal (0.2%). Conclusions: The pooled prevalence of neural autoantibodies in patients with epilepsy of unknown etiology is small but not irrelevant. None of the controls had a positive result. There was high heterogeneity among studies. In the future, a homogeneous protocol for testing neural autoantibodies is recommended.


2017 ◽  
Vol 40 (3) ◽  
pp. 234-252 ◽  
Author(s):  
Gemma L. McKeon ◽  
Gail A. Robinson ◽  
Alexander E. Ryan ◽  
Stefan Blum ◽  
David Gillis ◽  
...  

2017 ◽  
Vol 68 ◽  
pp. 57-65 ◽  
Author(s):  
Le Zhang ◽  
Meng-Qian Wu ◽  
Zi-Long Hao ◽  
Siew Mun Vance Chiang ◽  
Kun Shuang ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document