scholarly journals Central venous catheter-related infections in hematology and oncology: 2012 updated guidelines on diagnosis, management and prevention by the Infectious Diseases Working Party of the German Society of Hematology and Medical Oncology

2014 ◽  
Vol 25 (5) ◽  
pp. 936-947 ◽  
Author(s):  
M. Hentrich ◽  
E. Schalk ◽  
M. Schmidt-Hieber ◽  
I. Chaberny ◽  
S. Mousset ◽  
...  
2020 ◽  
Vol 100 (1) ◽  
pp. 239-259
Author(s):  
Boris Böll ◽  
Enrico Schalk ◽  
Dieter Buchheidt ◽  
Justin Hasenkamp ◽  
Michael Kiehl ◽  
...  

AbstractCancer patients frequently require central venous catheters for therapy and parenteral nutrition and are at high risk of central venous catheter–related infections (CRIs). Moreover, CRIs prolong hospitalization, cause an excess in resource utilization and treatment cost, often delay anti-cancer treatment, and are associated with a significant increase in mortality in cancer patients. We therefore summoned a panel of experts by the Infectious Diseases Working Party (AGIHO) of the German Society of Hematology and Medical Oncology (DGHO) and updated our previous guideline on CRIs in cancer patients. After conducting systematic literature searches on PubMed, Medline, and Cochrane databases, video- and meeting-based consensus discussions were held. In the presented guideline, we summarize recommendations on definition, diagnosis, management, and prevention of CRIs in cancer patients including the grading of strength of recommendations and the respective levels of evidence. This guideline supports clinicians and researchers alike in the evidence-based decision-making in the management of CRIs in cancer patients.


2014 ◽  
Vol 93 (7) ◽  
pp. 1083-1095 ◽  
Author(s):  
Olaf Penack ◽  
Carolin Becker ◽  
Dieter Buchheidt ◽  
Maximilian Christopeit ◽  
Michael Kiehl ◽  
...  

2006 ◽  
Vol 27 (9) ◽  
pp. 964-968 ◽  
Author(s):  
Shunji Takakura ◽  
Naoko Fujihara ◽  
Takashi Saito ◽  
Terumi Kimoto ◽  
Yutaka Ito ◽  
...  

Objective.To examine whether intervention by infectious diseases physicians (IDPs) in the treatment decisions that emphasize adequate antifungal treatment and early removal of central venous catheter for patients with Candida bloodstream infection (BSI) improves prognosis.Design.Retrospective cohort study of patients with Candida BSI, comparing the prognosis of patients before and after the start of the intervention.Setting.A 1,240-bed, tertiary care university hospital.Patients.Forty patients with Candida BSI during a 2-year period, from January 2001 to December 2002, were included in the study Twenty-three patients in the first year after the start of intervention by IDPs (intervention group) were compared with 17 patients in the first year before the start of the IDP intervention (baseline group).Interventions.In January 2002, a total of 5 IDPs at Kyoto University Hospital gave unsolicited recommendations on antifungal treatment and advised all physicians treating inpatients who had Candida BSI to remove the central venous catheter.Results.No significant difference was seen between the 2 groups in patients' clinical background, species, and fluconazole susceptibility of the causative organisms. The 30-day survival rate was significantly better in the intervention group (18 [78%] of 23 patients) than in the baseline group (7 [44%] of 16 patients; P = .04 by Fisher's exact test). More patients in the intervention group than in the baseline group received appropriate antifungal therapy (81% vs 50%) and had their central venous catheter removed at an appropriate time (95% vs 81%)Conclusion.The introduction of an active system of IDP consultation for every case of Candida BSI in our hospital substantially improved patient outcomes.


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