scholarly journals A systematic review of the role of pulmonary irradiation in the management of primary bone tumours

2002 ◽  
Vol 13 (1) ◽  
pp. 23-30 ◽  
Author(s):  
J.S. Whelan ◽  
R.J. Burcombe ◽  
J. Janinis ◽  
A.M. Baldelli ◽  
A.M. Cassoni
Keyword(s):  
Systematic Review ◽  
Bone Tumours ◽  
Primary Bone ◽  
Primary Bone Tumours

scholarly journals The Role of Osteocalcin and Alkaline Phosphatase Immunohistochemistry in Osteosarcoma Diagnosis

2018 ◽  
Vol 2018 ◽  
pp. 1-5 ◽  
Author(s):  
Hasrayati Agustina ◽  
Ita Asyifa ◽  
Afiati Aziz ◽  
Bethy S. Hernowo
Keyword(s):  
Alkaline Phosphatase ◽  
Positive Predictive Value ◽  
Predictive Value ◽  
Bone Tumours ◽  
Small Specimen ◽  
Primary Bone ◽  
The Mean ◽  
Sensitivity Specificity ◽  
Primary Bone Tumours

Background. The diagnosis of Osteosarcoma (OSA) is not always straightforward. OSA may resemble Other Primary Bone Tumours (OPBT). The diagnosis of osteosarcoma is sometimes difficult especially in a very small specimen. Immunohistochemistry is one of ancillary testing types that can help the diagnosis of many tumours. The aim of this study was to evaluate the validity of Osteocalcin (OCN) and Alkaline Phosphatase (ALP) immunohistochemistry in discriminating OSA from OPBT. Method. This study included 50 selected human primary bone tumours, 25 cases of OSA and 25 cases of OPBT. Immunohistochemical evaluation of OCN and ALP was done for all cases. The sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and overall accuracy were calculated. Result. The mean age of OSA and OPBT patients was 19.6±13.6 and 40.0±16.3 years, respectively. Osteocalcin was positive in 17/25 (68%) cases of OSA and 16/25 (64%) cases of OPBT (p=0.061). Alkaline Phosphatase was positive in 24/25 (96%) cases of OSA and 5/25 (20%) cases of OPBT (p<0.001). The sensitivity of OCN in OSA diagnosis was 68%, with specificity, PPV, NPV, and overall accuracy being 36%, 52%, 53%, and 52%, respectively. The sensitivity of ALP in OSA diagnosis was 96%, with specificity, PPV, NPV, and overall accuracy being 80%, 82.7%, 95.2%, and 88%, respectively. Conclusion. ALP immunohistochemistry is useful in discriminating OSA from OPBT. ALP is superior to OCN in OSA diagnosis. OCN cannot be used to differentiate between OSA and OPBT.

Porous tantalum acetabular cups for reconstructions after peri-acetabular resections of primary bone tumours

2021 ◽  
pp. 112070002110015
Author(s):  
Riccardo Zucchini ◽  
Andrea Sambri ◽  
Claudio Giannini ◽  
Michele Fiore ◽  
Carlotta Calamelli ◽  
...  
Keyword(s):  
Bone Tumour ◽  
Hip Dislocation ◽  
Functional Results ◽  
Bone Tumours ◽  
Harris Hip Score ◽  
Porous Tantalum ◽  
Term Survival ◽  
Primary Bone ◽  
Primary Bone Tumours

Introduction: Periacetabular reconstruction after resection of primary bone tumour is a very demanding procedure. They are frequently associated with scarce functional results and a high rate of complications. We report a series of patients with periacetabular resections for primary bone tumours and reconstruction with a porous tantalum (PT) acetabular cup (AC). Materials and methods: 27 patients (median age 30 years) were included, being affected by primary bone tumours of the pelvis and treated with peri-acetabular resection and reconstruction with a PT AC. The diagnoses were 13 osteosarcomas, 7 chondrosarcomas and 7 Ewing sarcomas. Function was assessed with the Harris Hip Score and complications were classified according to Zeifang. Results: The median follow-up was 70 months. 1 patient required removal of the PT AC because of implant associated infection 55 months after surgery. There was 1 hip dislocation and no case of aseptic loosening. At final follow-up, the median HHS was 81 points (range 48–92). Conclusions: The used PT AC had good medium-term survival rates and good functional results. This technique is a viable reconstructive option after resections of periacetabular primary bone sarcomas.

Primary Bone Tumours of the Pelvis in Childhood—Ewing's Sarcoma of the Ilium, Pubis and Ischium. (Report of 30 cases) (Part I)

1989 ◽  
Vol 33 (4) ◽  
pp. 354-360 ◽  
Author(s):  
K. KOZLOWSKI ◽  
J. CAMPBELL ◽  
G. BELUFFI ◽  
J.C. HOEFFEL ◽  
L. MORRIS ◽  
...  
Keyword(s):  
Ewing’S Sarcoma ◽  
Ewing's Sarcoma ◽  
Bone Tumours ◽  
Primary Bone ◽  
Primary Bone Tumours

Endoprosthetic reconstruction of the distal tibia and ankle joint after resection of primary bone tumours

2009 ◽  
Vol 91-B (10) ◽  
pp. 1378-1382 ◽  
Author(s):  
A. S. Shekkeris ◽  
S. A. Hanna ◽  
M. D. Sewell ◽  
B. G. I. Spiegelberg ◽  
W. J. S. Aston ◽  
...  
Keyword(s):  
Ankle Joint ◽  
Distal Tibia ◽  
Bone Tumours ◽  
Endoprosthetic Reconstruction ◽  
Primary Bone ◽  
Primary Bone Tumours

Magnetic Resonance Imaging of Primary Bone Tumours

1990 ◽  
pp. 137-150
Author(s):  
J. Gielen ◽  
A. L. Baert ◽  
G. Marchal ◽  
P. Demaerel ◽  
L. Vanfraeyenhoven ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Bone Tumours ◽  
Resonance Imaging ◽  
Primary Bone ◽  
Primary Bone Tumours

Bone cancer

2020 ◽  
pp. 4709-4713
Author(s):  
Helen Hatcher
Keyword(s):  
Metastatic Disease ◽  
Ewing Sarcoma ◽  
Bone Biopsy ◽  
Tumour Size ◽  
External Beam Radiotherapy ◽  
Bone Tumours ◽  
Malignant Bone Tumours ◽  
Primary Bone ◽  
Bony Metastases ◽  
Primary Bone Tumours

Benign bone tumours are common, usually asymptomatic, and discovered incidentally. Malignant primary bone tumours are uncommon but cause significant morbidity and mortality, particularly in adolescents and young adults. Bony metastases are the tumours most frequently seen in bone. Malignant bone tumours typically present with localized pain or swelling. With patients in whom the diagnosis is not clearly metastatic disease, determination of tumour size and extent is best achieved by magnetic resonance imaging, and bone biopsy is mandatory to establish a precise histological diagnosis. Osteosarcoma, chondrosarcoma, and Ewing sarcoma are the three commonest primary bone tumours. In determining management, the main clinical distinction is between localized and metastatic disease. Non-metastatic primary tumours are treated with surgery (when possible) and chemotherapy (osteosarcoma and Ewing sarcoma, sometimes chondrosarcoma). Symptomatic bony metastases are usually treated with external beam radiotherapy.

Primary Bone Tumours and Tumour-Like Lesions

2016 ◽  
pp. 501-519
Author(s):  
Reiner Bartl ◽  
Christoph Bartl
Keyword(s):  
Bone Tumours ◽  
Primary Bone ◽  
Primary Bone Tumours
Sign in / Sign up

Export Citation Format

Share Document