scholarly journals Relationship Between Urinary Albumin Excretion and Blood Pressure in the Community Pharmacy: The Palmera Study

2012 ◽  
Vol 26 (1) ◽  
pp. 3-4 ◽  
Author(s):  
J. Sendra-Lillo ◽  
D. Sabater-Hernandez ◽  
A. de la Sierra ◽  
A. Sendra-Ortola ◽  
A. Denia-Tomas ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Community Pharmacy ◽  
Urinary Albumin Excretion ◽  
Urinary Albumin ◽  
Albumin Excretion

Relationship Between Blood Pressure and Urinary Albumin Excretion in Development of Microalbuminuria

Diabetes ◽  
1990 ◽  
Vol 39 (2) ◽  
pp. 245-249 ◽  
Author(s):  
E. R. Mathiesen ◽  
B. Ronn ◽  
T. Jensen ◽  
B. Storm ◽  
T. Deckert
Keyword(s):  
Blood Pressure ◽  
Urinary Albumin Excretion ◽  
Urinary Albumin ◽  
Albumin Excretion

Urinary albumin excretion and blood pressure in the general population

1989 ◽  
Vol 76 (1) ◽  
pp. 39-42 ◽  
Author(s):  
Peter Gosling ◽  
D. G. Beevers
Keyword(s):  
Blood Pressure ◽  
General Population ◽  
Urinary Albumin Excretion ◽  
Excretion Rate ◽  
Albumin Excretion Rate ◽  
Urinary Albumin ◽  
Albumin Excretion ◽  
Arterial Blood ◽  
Blood Pressures ◽  
Excretion Rates

1. Twenty-four hour urinary albumin excretion rate was measured by a sensitive radioimmunoassay in 99 male and 100 female randomly selected factory workers, aged between 20 and 60 years. 2 The median (range) albumin excretion rates for men and women of 4.67 (1.0–25.8) and 5.25 (0.2–33.0) mg/24 h, respectively, were not significantly different. 3. No correlation was established between diastolic, systolic or mean arterial blood pressure and albumin excretion rate for the whole group. 4. Twenty-eight subjects with systolic and/or diastolic blood pressures ≥ 140/90 mmHg (18.7/12.0 kPa) showed a positive correlation between mean arterial blood pressure and albumin excretion rate (r = 0.412,P < 0.01). 5. There was no significant relationship between number of cigarettes smoked, age or alcohol intake and albumin excretion rate. 6. The data suggest that in the general population albumin excretion rate is variable and not dependent on blood pressure, but at blood pressures > 140/90 mmHg (18.7/12.0 kPa) albumin excretion rate may become pressure dependent, although high albumin excretion rates were sometimes found in subjects with blood pressures < 140/90 mmHg (18.7/12.0 kPa).

Urinary Albumin Excretion and Atherosclerosis in Essential Hypertension

1997 ◽  
Vol 92 (1) ◽  
pp. 45-50 ◽  
Author(s):  
Roberto Pedrinelli ◽  
Klaus Undpaintner ◽  
Giulia Dell'omo ◽  
Vinicio Napoli ◽  
Vitantonio Di Bello ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Essential Hypertension ◽  
Angiotensin Converting Enzyme ◽  
Systolic Blood Pressure ◽  
Urinary Albumin Excretion ◽  
Urinary Albumin ◽  
Cardiac Mass ◽  
Converting Enzyme ◽  
Albumin Excretion ◽  
Angiotensin Converting Enzyme Genotype

1. Increased urinary albumin excretion is common in patients with essential hypertension and is at least to some extent correlated with prevailing blood pressure levels. However, the generalized vascular dysfunction present in advanced atherosclerotic disease may independently influence this parameter. 2. To evaluate this possibility, we assessed blood pressure, ultrasonographic carotid thickness, cardiac mass, minimum forearm vascular resistances, metabolic parameters and the angiotensin-converting enzyme genotype in patients with untreated essential hypertension and atherosclerotic peripheral vascular disease (n = 11). The results were compared with similar data obtained in matched groups of patients with uncomplicated hypertension and with normotensive control subjects (n = 11 per group). 3. Urinary albumin excretion was higher in hypertensive patients with atherosclerosis than in those without complications; carotid thickness was higher in atherosclerotic patients and a positive, statistically significant correlation existed between this parameter and urinary albumin excretion. In the same patient group, systolic blood pressure, fasting insulin and triacylglycerol levels were elevated and correlated with urinary albumin levels. However, differences in urinary albumin excretion persisted after taking into account the influence of those parameters by analysis of covariance. The distribution of angiotensin-converting enzyme genotype patterns and values of cardiac mass and minimum forearm vascular resistances did not differ significantly among the experimental groups. 4. The data suggest that vascular status may influence urinary albumin excretion in patients with essential hypertension, while confirming the importance of systolic blood pressure levels as a determinant of the raised urinary albumin excretion.

scholarly journals The impact of hormonal contraceptives on blood pressure, urinary albumin excretion and glomerular filtration rate

2007 ◽  
Vol 63 (2) ◽  
pp. 224-231 ◽  
Author(s):  
Jarir Atthobari ◽  
Ron T. Gansevoort ◽  
Sipke T. Visser ◽  
Paul E. de Jong ◽  
Lolkje T. W. de Jong-van den Berg ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Glomerular Filtration Rate ◽  
Glomerular Filtration ◽  
Filtration Rate ◽  
Urinary Albumin Excretion ◽  
Urinary Albumin ◽  
Hormonal Contraceptives ◽  
Albumin Excretion ◽  
The Impact

β-Adrenoceptor and GRK3 expression in human lymphocytes is related to blood pressure and urinary albumin excretion

2010 ◽  
pp. 1 ◽  
Author(s):  
Eduardo Oliver ◽  
Eduardo Rovira ◽  
Fermí Montó ◽  
Carmen Valldecabres ◽  
Raul Julve ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Urinary Albumin Excretion ◽  
Human Lymphocytes ◽  
Urinary Albumin ◽  
Albumin Excretion

scholarly journals Independent Determinants of Urinary Albumin Excretion and Confounding Variables in Type 2 Diabetic Patient

2016 ◽  
Vol 1 (1) ◽  
Keyword(s):  
Blood Pressure ◽  
Uric Acid ◽  
Risk Factor ◽  
Serum Uric Acid ◽  
Biochemical Parameters ◽  
Urinary Albumin Excretion ◽  
Urinary Albumin ◽  
Diabetic Patients ◽  
Albumin Excretion ◽  
Confounding Variables

Background: Microalbuminuria is a known risk factor for the development of clinical nephropathy in diabetes and also an independent risk factor for cardiovascular disease. Microalbuminuria is a marker of a pathophysiological process that causes both increased renal albumin loss and atherothrombosis. Microalbuminuria is hallmark for early detection of diabetic nephropathy. An elevated urinary albumin excretion is a marker of endothelial dysfunction that symbolizes the kidney’s way to translate the existence of vascular damage. The aim of this study was to evaluate the independent determinants of urinary albumin excretion, and association between biochemical parameters and socio-demographic factors in Diabetic patients. Materials and Methods: This is a hospital based cross sectional study included diagnosed case of Diabetic patients. Serum uric acid concentrations were measured by enzymatic method (uricase-peroxidase), HbA1c was measured using the principle of dry chemistry, Blood Sugar measured by Glucose oxidase peroxidase (GOD/POD) method and urinary albumin excretion was measured with an immunoturbidometric assay. Results: Based on categorization of Urinary albumin excretion, 65% normoalbuminuric, 27% microalbuminuric and 8% macroalbuminuric are found in our study population. The frequency of hyperuricemia was found to be 43%. The prevalence of albuminuria ncreased significantly with increasing glycaemia. Pearsons Correlation coefficient by bivariate analysis of Urinary albumin excretion with confounding variables shows significant positive correlation with onset of DM (r=0.203, P=0.013), Systolic Blood Pressure (r=0.355, P=0.001), Diastolic Blood Pressure (r=0.405, P=0.001), Uricacid (r=0.352, P=0.001), HbA1c (r=0.212, P=0.005) and Smoking (r=0.265, P=0.01). Multiple regression test shows that independent determinant of UAE are Blood Pressure {Diastolic (β=0.313, P=0.006) /Systolic (β=0.309, P=0.002)}, HbA1c (β=0.187, P=0.010), Uric acid (β=0.331, P=0.0001) and Onset of DM (β=0.199,P=0.041). Conclusion: Albuminuria is therefore an important risk factor to measure in patients at risk. The findings extend the relationship between confounding variables and the urinary albumin excretion which emphasize on the importance of screening for icroalbuminuria, Serum Uric Acid to prevent renal dysfunction, HbA1c measurement on a regular interval for good glycemic control and the other variables for regular physiological process of body. Further examination is needed in a large population size to clarify the validity between the biochemical parameters

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