scholarly journals Total Exposure and Exposure Rate Effects for Alcohol and Smoking and Risk of Head and Neck Cancer: A Pooled Analysis of Case-Control Studies

2009 ◽  
Vol 170 (8) ◽  
pp. 937-947 ◽  
Author(s):  
J. H. Lubin ◽  
M. Purdue ◽  
K. Kelsey ◽  
Z.-F. Zhang ◽  
D. Winn ◽  
...  
Keyword(s):  
Head And Neck Cancer ◽  
Head And Neck ◽  
Neck Cancer ◽  
Pooled Analysis ◽  
Case Control ◽  
Exposure Rate ◽  
Case Control Studies ◽  
Total Exposure ◽  
Rate Effects

scholarly journals Estimating and explaining the effect of education and income on head and neck cancer risk: INHANCE consortium pooled analysis of 31 case-control studies from 27 countries

2014 ◽  
Vol 136 (5) ◽  
pp. 1125-1139 ◽  
Author(s):  
David I. Conway ◽  
Darren R. Brenner ◽  
Alex D. McMahon ◽  
Lorna M.D. Macpherson ◽  
Antonio Agudo ◽  
...  
Keyword(s):  
Head And Neck Cancer ◽  
Cancer Risk ◽  
Head And Neck ◽  
Neck Cancer ◽  
Pooled Analysis ◽  
Case Control ◽  
Case Control Studies

scholarly journals Vitamin D in Head and Neck Cancer: a Systematic Review

2020 ◽  
Vol 23 (1) ◽  
Author(s):  
Antti Mäkitie ◽  
Iida Tuokkola ◽  
Göran Laurell ◽  
Outi Mäkitie ◽  
Kerry Olsen ◽  
...  
Keyword(s):  
Vitamin D ◽  
Head And Neck Cancer ◽  
Head And Neck ◽  
Vitamin D Deficiency ◽  
Neck Cancer ◽  
Cancer Diagnosis ◽  
Case Control ◽  
Healthy Population ◽  
Inverse Association ◽  
Case Control Studies

Abstract Purpose of review Observational studies have shown that serum 25-OH vitamin D [25(OH)D] is inversely associated with overall cancer risk in many malignancies. We performed a systematic literature review to determine whether vitamin D deficiency is related to head and neck cancer (HNC) etiology and outcome. Recent findings The search yielded five prospective studies reporting 25(OH)D levels prior to cancer diagnosis and their effect on the risk of HNC. Eight studies were cross-sectional or case-control studies, in which 25(OH)D levels were only measured after cancer diagnosis. Two studies found an inverse association between 25(OH)D level and HNC risk, while two other prospective cohort studies demonstrated no connection between 25(OH)D and HNC risk. Several studies reported cancer patients to have significantly lower 25(OH)D levels than controls. Associations between 25(OH)D and prognosis and mortality were variable. Summary The link between vitamin D and HNC has so far only been investigated in a few observational, prospective, and case-control studies. Vitamin D deficiency may be more common in HNC patients than in the healthy population. There is no evidence for a causal relationship. Further studies are needed to evaluate whether low 25(OH)D concentrations play a role in the development or outcome of HNCs.

scholarly journals Low human papillomavirus prevalence in head and neck cancer: results from two large case–control studies in high-incidence regions

2011 ◽  
Vol 40 (2) ◽  
pp. 489-502 ◽  
Author(s):  
Karina Braga Ribeiro ◽  
José Eduardo Levi ◽  
Michael Pawlita ◽  
Sérgio Koifman ◽  
Elena Matos ◽  
...  
Keyword(s):  
Head And Neck Cancer ◽  
Human Papillomavirus ◽  
Head And Neck ◽  
Neck Cancer ◽  
Case Control ◽  
Case Control Studies ◽  
High Incidence ◽  
Large Case

Head and neck cancer among marijuana users: A meta-analysis of matched case–control studies

2015 ◽  
Vol 60 (12) ◽  
pp. 1750-1755 ◽  
Author(s):  
M.F.F. de Carvalho ◽  
M.R. Dourado ◽  
I.B. Fernandes ◽  
C.T.P. Araújo ◽  
A.T. Mesquita ◽  
...  
Keyword(s):  
Head And Neck Cancer ◽  
Head And Neck ◽  
Neck Cancer ◽  
Meta Analysis ◽  
Case Control ◽  
Case Control Studies ◽  
Matched Case

scholarly journals Genetic Association betweenNFKBIAandNFKB1Gene Polymorphisms and the Susceptibility to Head and Neck Cancer: A Meta-Analysis

2019 ◽  
Vol 2019 ◽  
pp. 1-10 ◽  
Author(s):  
Lin Li ◽  
Zhong-Ti Zhang
Keyword(s):  
Head And Neck Cancer ◽  
Head And Neck ◽  
Neck Cancer ◽  
Web Of Science ◽  
Meta Analysis ◽  
Case Control ◽  
Statistical Correlation ◽  
Case Control Studies ◽  
The Relationship

Background. The role of theNFKB1gene rs28362491 polymorphism andNFKBIAgene rs2233406 polymorphism in the development of head and neck cancer (HNC) remains controversial. This meta-analysis was performed to assess the relationship between the gene polymorphisms and HNC quantitatively.Methods. PubMed, Embase, Web of Science, WanFang Data, and China National Knowledge databases were used to search for eligible articles. The relationship was evaluated by STATA 11.0.Results. Eight eligible articles were included in our study. Nine case-control studies from the eight included articles were correlated with rs28362491 polymorphism. Four articles were related to rs2233406 polymorphism. Overall, a significant correlation was observed between the rs28362491 polymorphism and a decreased risk of HNCs (OR=0.76,95%CI=0.60‐0.97for DD vs. II;OR=0.80,95%CI=0.68‐0.95for DD vs. DI+II). In subgroup analyses, the rs28362491 polymorphism was associated with the risk of nasopharyngeal carcinoma (NC), but not with oral cancer (OC). In addition, no statistical correlation was found between the polymorphism of rs2233406 and HNCs.Conclusion. rs28362491 polymorphism was significantly associated with the risk of HNCs, especially with NC. Additionally, our results showed that no association was discovered between rs2233406 polymorphism and HNCs.

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