scholarly journals Life Course Path Analysis of Birth Weight, Childhood Growth, and Adult Systolic Blood Pressure

2009 ◽  
Vol 169 (10) ◽  
pp. 1167-1178 ◽  
Author(s):  
M. Gamborg ◽  
P. K. Andersen ◽  
J. L. Baker ◽  
E. Budtz-Jorgensen ◽  
T. Jorgensen ◽  
...  
2011 ◽  
Vol 26 (7) ◽  
pp. 1115-1121 ◽  
Author(s):  
Andrea F. Duncan ◽  
Roy J. Heyne ◽  
Janet S. Morgan ◽  
Naveed Ahmad ◽  
Charles R. Rosenfeld

2015 ◽  
Vol 33 (8) ◽  
pp. 1542-1548 ◽  
Author(s):  
Markus Juonala ◽  
Michael M.H. Cheung ◽  
Matthew A. Sabin ◽  
David Burgner ◽  
Michael R. Skilton ◽  
...  

PLoS Medicine ◽  
2011 ◽  
Vol 8 (6) ◽  
pp. e1000440 ◽  
Author(s):  
Andrew K. Wills ◽  
Debbie A. Lawlor ◽  
Fiona E. Matthews ◽  
Avan Aihie Sayer ◽  
Eleni Bakra ◽  
...  

2015 ◽  
Vol 7 (3) ◽  
pp. 306-313 ◽  
Author(s):  
S. Sandboge ◽  
C. Osmond ◽  
E. Kajantie ◽  
J. G Eriksson

Previous studies suggest that the inverse association between birth weight and adult blood pressure amplifies with age. Rapid childhood growth has also been linked to hypertension. The objective of this study was to determine whether the association between childhood growth and adult blood pressure amplifies with age. The study comprised 574 women and 462 men from the Helsinki Birth Cohort Study who attended a clinical study in 2001–2004 and a follow-up in 2006–2008. Mean age at the clinic visits was 61.5 and 66.4 years, respectively. Blood pressure was measured at both occasions. Conditional growth models were used to assess relative weight gain and linear growth. We studied the associations between conditional growth and blood pressure as well as the presence of hypertension. Relative weight gain and linear growth between ages 2 and 11 years were inversely associated with systolic blood pressure at mean age 66.4 years, after adjustment for sex, blood pressure at mean age 61.5 years, as well as other covariates. A one s.d. increase in linear growth between 2 and 11 years was associated with an OR of 0.61 for hypertension at mean age 66.4 years. Contrary to previous studies, we have shown an inverse association between childhood growth and adult blood pressure. There were, however, no associations between childhood growth and systolic blood pressure at mean age 61.5 years indicating that the beneficial effects of a more rapid than expected childhood growth might become more apparent with increasing age.


1997 ◽  
Vol 15 (12) ◽  
pp. 1627-1631 ◽  
Author(s):  
Peter M. Nilsson ◽  
Per-Olof Östergren ◽  
Per Nyberg ◽  
Margareta Söderström ◽  
Peter Allebeck

2019 ◽  
Vol 10 (6) ◽  
pp. 621-626
Author(s):  
K. D. Mann ◽  
L. Basterfield ◽  
C. Wright ◽  
K. Parkinson ◽  
J. K. Reilly ◽  
...  

AbstractBirth weight and early growth have been associated with later blood pressure. However, not all studies consistently find a significant reduction in blood pressure with an increase in birth weight. In addition, the relative importance of birth weight and of other lifestyle and environmental factors is often overlooked and the association is rarely studied in adolescents. We investigated early life predictors, including birth weight, of adolescent blood pressure in the Gateshead Millennium Study (GMS). The GMS is a cohort of 1029 individuals born in 1999–2000 in Gateshead in Northern England. Throughout infancy and early childhood, detailed information were collected, including birth weight and measures of height and weight. Assessments of 491 returning participants at age 12 years included measures of body mass and blood pressure. Linear regression and path analysis were used to determine predictors and their relative importance on blood pressure. Birth weight was not directly associated with blood pressure at the age of 12. However, after adjustment for contemporaneous body mass index (BMI), an inverse association of standardized birth weight on systolic blood pressure was significant. The relative importance of birth weight on later systolic blood pressure was smaller than other contemporaneous body measures (height and BMI). There was no independent association of birth weight on blood pressure seen in this adolescent population. Contemporaneous body measures have an important role to play. Lifestyle factors that influence body mass or size, such as diet and physical activity, where interventions are directed at early prevention of hypertension should be targeted.


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