scholarly journals Specifying ICD9, ICPC and ATC codes for the STOPP/START criteria: a multidisciplinary consensus panel

2014 ◽  
Vol 43 (6) ◽  
pp. 773-778 ◽  
Author(s):  
Dominique A. de Groot ◽  
Marloes de Vries ◽  
Karlijn J. Joling ◽  
Jos P. C. M. van Campen ◽  
Jacqueline G. Hugtenburg ◽  
...  

Abstract Background: the STOPP/START criteria are a promising framework to increase appropriate prescribing in the elderly in clinical practice. However, the current definitions of the STOPP/START criteria are rather non-specific, allowing undesirable variations in interpretation and thus application. The aim of this study was to design specifications of the STOPP/START criteria into international disease and medication codes to facilitate computerised extraction from medical records and databases. Methods: a three round consensus procedure with a multidisciplinary expert panel was organised to prepare, judge and agree on the design of the STOPP/START criteria specifications in corresponding international disease codes (ICD9 and ICPC) and medication codes (ATC). Results: after two rounds consensus was reached for 74% of the STOPP criteria and for 73% of the START criteria. After three rounds full consensus was reached resulting in a specification of 61 out of 62 STOPP criteria and 26 START criteria with their corresponding codes. One criterion could not be specified and for some criteria corresponding disease codes were lacking or imperfect. Conclusion: this study showed the necessity of a consensus procedure as even experts frequently differed on how to specify the STOPP/START criteria. This specification enables next steps such as prognostic validation of these criteria on adverse outcomes and studying the impact of improving appropriate prescribing in the elderly.

2020 ◽  
Vol 10 (4) ◽  
pp. 312-315
Author(s):  
Olga Berdina ◽  
Irina Madaeva ◽  
Liubov Rychkova

In the literature, there are suggestions of a possible mutual influence between obstructive sleep apnea (OSA) and the novel coronavirus disease 2019 (COVID-19). The aim of this review is to analyze data found in the literature related to pathogenetic aspects of the impact of OSA on COVID-19, and vice versa, and features of the course of this comorbidity in both adulthood and childhood. Information was searched in MEDLINE, PubMed, EBSCO, and RSCI databases, which presented some data for the connection between COVID-19 and OSA, as well as aspects of OSA and COVID-19 comorbidity for adults and the elderly. The common pathophysiological pathways leading to increased systemic inflammation and adverse consequences of OSA and COVID-19 infection do coexist and were revealed in detail. We paid special attention to aspects of this comorbidity in children and found that research in this area was lacking. Based on this information, it should be concluded that: 1) more pediatric studies of links between OSA and COVID-19 are urgently needed; 2) screening hospitalized COVID-19 patients with tools to detect OSA could identify those at risk for a severe course of these diseases and adverse outcomes; 3) treating OSA will allow increasing the likelihood of developing a robust and long-lasting post-COVID-19 adaptive immunity in these patients.


2012 ◽  
Vol 2012 ◽  
pp. 1-7 ◽  
Author(s):  
Nazmi Krasniqi ◽  
Diana Segalada ◽  
Thomas F. Lüscher ◽  
Kurt Lippuner ◽  
Laurent Haegeli ◽  
...  

Background. Falls and fractures in the elderly are among the leading causes of disability. We investigated whether pacemaker implantation prevents falls in patients with SND in a large cohort of patients.Methods. Patient demographics and medical history were collected prospectively. Fall history was retrospectively reconstituted from available medical records. The 10-year probability for major osteoporotic fractures was calculated retrospectively from available medical records using the Swiss fracture risk assessment tool FRAX-Switzerland.Results. During a mean observation period of 2.3 years after implantation, the rates of fallers and injured fallers with fracture were reduced to 15% and 6%, respectively. This corresponds to a relative reduction in the number of fallers of 75% (P<0.001) and of injured fallers of 63% (P=0.014) after pacemaker implantation. Similarly, the number of falls was reduced from 60 (48%) before pacemaker implantation to 22 (18%) thereafter (relative reduction 63%,P=0.035) and the number of falls with injury from 22 (18%) to 7 (6%), which corresponds to a relative reduction of 67%,P=0.013.Conclusion. In patients with SND, pacemaker implantation significantly reduces the number of patients experiencing falls, the total number of falls, and the risk for osteoporotic fractures.


Author(s):  
Nguyen Patrick Viet-Quoc ◽  
Pelletier Lucie ◽  
Payot Isabelle ◽  
Latour Judith

Objectives: To design the Drug Delirium Scale (DDS), an evaluation tool to assess the drug burden in delirium in the elderly population. Design: We proceeded with a systematic literature review through database and grey literature. The records were examined by two independent reviewers using the inclusion and exclusion criteria. Data from the selected studies was extracted and a summary chart was written for each drug. Drugs in anticholinergic drug scales, Beers and STOPP criteria for anticholinergic of cognitive impairment effects were also included for evaluation. These summaries were submitted to the geriatric expert panel composed of two geriatric physicians and two geriatric pharmacists. The panel chose each drug included in the DDS list and their rank. Results: 981 records were identified and 149 met inclusion criteria. The expert panel evaluated 265 drugs and selected 96 drugs for the DDS scale. The mean interrater reliability score was of 0,634 [CI: 0,441; 0,791]. Conclusion: The Delirium Drug Scale (DDS) is the first evaluation tool to assess the risk of delirium derived from drugs used in the elderly population. It was designed using a sound methodological process. The DDS must now be tested in the geriatric population to validate its predictive value for delirium.


2015 ◽  
Vol 143 (3-4) ◽  
pp. 174-179 ◽  
Author(s):  
Darko Ilic ◽  
Zoran Bukumiric ◽  
Slobodan Jankovic

Introduction. Problems with polypharmacy, adverse drug reactions and non-adherence are especially frequent among elderly nursing home residents. Objective. The aim of our study was to evaluate effectiveness of a specific form of staff education on appropriateness of prescribing in a cluster of nursing homes for the elderly. Methods. The study was designed as before-and-after trial of educational intervention on appropriateness of prescribing in nursing homes for the elderly. In total 20 nursing homes located in Belgrade, Serbia were included in the study with 104 elderly residents and 27 caring physicians. Appropriateness of prescribing was checked against Beers, START and STOPP criteria, before and 6 months after the intervention. Results. There were 349 inappropriately prescribed drugs according to Beers criteria before the intervention and 37 drugs six months after the intervention. According to STOPP criteria there were 70 drugs inappropriately prescribed before the intervention, and 20 drugs 6 months after. When both criteria are taken together, there is a significant difference between the average number of inappropriate drugs per patient before (3.4?0.5) and after (0.6?0.7) educational intervention (t=38.902; p<0.001). Finally, before the intervention 143 appropriate drugs were omitted according to START criteria, while 6 months after the intervention there were only 67 omissions. Conclusion. Simple, but well targeted educational interventions may improve polypharmacy and decrease inappropriate prescribing rate, contributing to a better care of elderly patients in nursing homes.


2016 ◽  
Vol 19 (5) ◽  
pp. 871-879 ◽  
Author(s):  
Andressa Stella Kuhn Correia da Rosa ◽  
Bruna Polanski Costa ◽  
Cássia Pinheiro Kapper ◽  
Gabriela Graça Soder Dalmas ◽  
Lissiê Lunardi Sbroglio ◽  
...  

Abstract Identified the inappropriate prescription of drugs in elderly assisted geriatric outpatient clinic in the region of Vale do Rio Pardo in Rio Grande do Sul according to the criteria of STOPP and START. Cross-sectional study of 221 elderly, based on retrospective analysis of medical records using comprehensive geriatric assessment data held in the first visit. Descriptive variables were age, sex, number of pathologies and number of medications in use. And the study variables were potentially inappropriate medications (MPI) and potentially omitted medications (MPO), according to the STOPP and START criteria. Descriptive statistics were performed with frequencies, means and standard deviations where appropriate. It was observed 157 (71%) female patients. The average age was 75 (±8.26) years, 49.8% in the range of 75-84 years. The average number of drugs was 3 (±2.27), with 22.63% using 5 or more medications. The average pathologies was 3.45 (±2.02). They identified 194 prescriptions of MPI and observed 93 MPO. The most identified were the MPI for the cardiovascular system, especially β noncardioselective blockers and acetylsalicylic acid. Also MPO were found most of the cardiovascular system, with emphasis on acetylsalicylic acid and inhibitors of angiotensin converting enzyme. This is sample of elderly with significant prevalence of inappropriate prescribing of drugs. Studies using the STOPP criteria and START in different health care settings can qualify the care provided to the elderly.


Cells ◽  
2021 ◽  
Vol 10 (12) ◽  
pp. 3373
Author(s):  
Anita Pirabe ◽  
Stefan Heber ◽  
Waltraud C. Schrottmaier ◽  
Anna Schmuckenschlager ◽  
Sonja Treiber ◽  
...  

The COVID-19 pandemic drastically highlighted the vulnerability of the elderly population towards viral and other infectious threats, illustrating that aging is accompanied by dysregulated immune responses currently summarized in terms like inflammaging and immunoparalysis. To gain a better understanding on the underlying mechanisms of the age-associated risk of adverse outcome in individuals experiencing a SARS-CoV-2 infection, we analyzed the impact of age on circulating monocyte phenotypes, activation markers and inflammatory cytokines including interleukin 6 (IL-6), IL-8 and tumor necrosis factor (TNF) in the context of COVID-19 disease progression and outcome in 110 patients. Our data indicate no age-associated differences in peripheral monocyte counts or subset composition. However, age and outcome are associated with differences in monocyte activation status. Moreover, a distinct cytokine pattern of IL-6, IL-8 and TNF in elderly survivors versus non-survivors, which consolidates over the time of hospitalization, suggests that older patients with adverse outcomes experience an inappropriate immune response, reminiscent of an inflammaging driven immunoparalysis. Our study underscores the value, necessity and importance of longitudinal monitoring in elderly COVID-19 patients, as dynamic changes after symptom onset can be observed, which allow for a differentiated insight into confounding factors that impact the complex pathogenesis following an infection with SARS-CoV-2.


2018 ◽  
Vol 71 (11-12) ◽  
pp. 368-376
Author(s):  
Kosana Stanetic ◽  
Vesna Kevic ◽  
Mirko Stanetic

Introduction. The number of people over 65 is increasing in the world, and falls are rather common among them. The objective of this research was to examine the impact of depression, dementia, the number of chronic diseases and the number of used medications in the risk of falls in the elderly. Material and Methods. We carried out a prospective study during the period from March 20 to May 20, 2016. The patients were interviewed, and data were also obtained from medical records. The data collection included a socio-demographic questionnaire, the Tinetti Gait and Balance Instrument, Beck Depression Inventory and the Folstein Mini-Mental State test to assess cognitive functions. Results. The study included 208 patients older than 65 years, 81 men, 127 women. The Tinetti Gait and Balance tool revealed that onethird (63) of patients were at a high risk of falls, 35 patients at a moderate risk, and 110 patients presented with a low risk of falls. The results of our study showed a statistically significant association between dementia (p = 0.000) and depression (p = 0.000) as the risks of falling. Patients with some chronic diseases and patients continuously taking various drugs were also at higher risk of falls. Conclusion. Timely detection and treatment of depression and dementia may contribute to reducing the risk of falls in the elderly. Patients? medication lists should be reviewed to decrease the number of medications or modify the dose. Family physicians play a major role in preventing falls in the elderly.


2016 ◽  
Vol 19 (2) ◽  
pp. 059
Author(s):  
Amin Bagheri ◽  
Ahmad Masoumi ◽  
Jamshid Bagheri

<strong>Background:</strong> Coronary endarterectomy (CE) is performed as an adjunct to coronary artery bypass surgery (CABG); however, the efficacy of this technique is still controversial. We aimed to evaluate the impact of CE combined with CABG when compared with isolated CABG.<br /><strong>Methods:</strong> Patients who underwent CABG between July 2007 and June 2014 were included. 70 of 2452 patients (2.8%) underwent CE in addition to CABG. Early results were compared with isolated CABG and predictors of adverse outcome were measured in stepwise multivariate logistic regression analyses.<br /><strong>Results:</strong> The incidence of comorbidities including prior myocardial infarction, diabetes mellitus, and three-vessel coronary disease in CE patients was higher; however, mortality (4.3% versus control 3.6%; P = .762) and postoperative complications were not significantly increased in this group of patients (except supraventricular arrhythmia). Although age greater than 70 years, impaired ejection fraction, intraoperative intraaortic balloon pump, and prolonged cardiopulmonary bypass time were important predictors of adverse outcomes, CE was not associated with increased mortality or postoperative morbidities. <br /><strong>Conclusion:</strong> Despite the higher risk profile of patients who underwent CE, this technique was not identified as an independent risk factor for adverse postoperative outcomes.


2020 ◽  
Vol 18 (3) ◽  
pp. 221-228
Author(s):  
Piotr Czarnecki ◽  
◽  
Justyna Podgórska-Bednarz ◽  
Lidia Perenc ◽  
◽  
...  

Introduction. Physical activity is known to be an important factor influencing health throughout human life. This issue has become crucial for public health due to the aging of the population in both developed and developing countries. Aim. is to present a literature review on the forms of physical activity undertaken by the elderly, as well as on issues related to physical activity and the population aging. Material and methods. The study was prepared on the basis of a review of Polish and foreign literature. The following databases and data sources were used: EBSCO, ScienceDirect and Google Scholar. An additional source of data were the websites of the Central Statistical Office. Strictly defined key phrases were used during the collection of literature. The work has been divided into thematic subsections on the aging of the society, the impact of physical activity on health and the main topic, i.e. forms of physical activity selected by the elderly. Analysis of the literature. The number of elderly people in Polish society has increased by almost 3.7 million over three decades. Therefore, an important topic is prophylaxis aimed at increasing the number of days in good health, largely covering the broadly understood activation of the elderly. The available data indicate that only 12% of elderly people undertake physical activity once a week. The most common form of spending free time actively is walking (as many as 73% of people in this population declare this form of physical activity in one of the presented studies). Conclusion. Organized forms of physical activity are undertaken much less frequently by the analyzed age group mainly due to financial limitations and limited availability of sports infrastructure.


2017 ◽  
Vol 2 (1) ◽  
pp. 1
Author(s):  
Amirul Amin Ismail ◽  
Ismail Samsuddin ◽  
Azman Zainonabidin ◽  
Harlina Mohd Ali

By the year 2030, Malaysian population will experience the after effects of the rapid growth of ageing society. This paper investigates the impact of seamless integration of horticultural activity in the new residential typology of retirement community. It is believed that horticultural therapy is not only beneficial for physical and psychological but also promotes socialisation opportunities among the elderly. Comparative analysis method on selected precedent studies has been carried out and analysed in accordance with Malaysian context. Initial findings indicate that a retirement community with horticultural activity gives therapy for healthier well-being. This therapeutic activity can be apositive change in elderly lifestyle and essential towards the establishment of retirement community in Malaysia. 


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