scholarly journals Pancreatic adenocarcinoma presenting with sudden onset bilateral deafness secondary to metastatic leptomeningeal infiltration

2012 ◽  
Vol 41 (6) ◽  
pp. 818-819 ◽  
Author(s):  
S. J. Blows ◽  
R. Morgan ◽  
U. Dhariwal ◽  
G. Petts ◽  
F. Roncaroli
Keyword(s):  
Pancreatic Adenocarcinoma ◽  
Sudden Onset ◽  
Leptomeningeal Infiltration ◽  
Bilateral Deafness

scholarly journals Sudden-onset bilateral deafness revealing early neurosyphilis

2014 ◽  
Vol 131 (6) ◽  
pp. 389-391 ◽  
Author(s):  
A.-L. Cassilde ◽  
G. Barnaud ◽  
S. Baccar ◽  
E. Mortier
Keyword(s):  
Sudden Onset ◽  
Bilateral Deafness

scholarly journals Sudden onset bilateral deafness as a presentation of chronic myeloid leukaemia

2012 ◽  
Vol 160 (1) ◽  
pp. 3-3
Author(s):  
Samah M. Alimam ◽  
Mohd K. Mamat ◽  
Samar Kulkarni ◽  
Tim C. P. Somervaille
Keyword(s):  
Chronic Myeloid Leukaemia ◽  
Myeloid Leukaemia ◽  
Sudden Onset ◽  
Bilateral Deafness

Sudden onset bilateral deafness during therapeutic leukapheresis

1993 ◽  
Vol 8 (3) ◽  
pp. 153-153
Author(s):  
Mark Silva ◽  
David Bareford
Keyword(s):  
Sudden Onset ◽  
Bilateral Deafness

Isolated deafness as a presenting symptom in granulomatosis with polyangiitis

2021 ◽  
Vol 14 (3) ◽  
pp. e241159
Author(s):  
Amy Kousha ◽  
Michael Reed ◽  
Sara Else
Keyword(s):  
Respiratory Tract ◽  
Granulomatosis With Polyangiitis ◽  
Organ Damage ◽  
Sudden Onset ◽  
Small Vessel Vasculitis ◽  
Upper Respiratory Tract ◽  
Diagnostic Uncertainty ◽  
Tract Involvement ◽  
Upper Respiratory ◽  
Bilateral Deafness

Granulomatosis with polyangiitis (GPA) is a rare small vessel vasculitis commonly affecting the lungs, upper respiratory tract and kidneys. It is an idiopathic condition but likely due to an autoimmune process, resulting in granulomatous lesions and glomerulonephritis. Upper respiratory tract involvement is commonly seen in patients with GPA. Our case is that of an elderly lady (Mrs C) presenting with sudden onset bilateral deafness. She was later found to have extensive lower respiratory tract involvement although she was never particularly symptomatic of this. The presentation suggested a single organ disorder and led to some initial diagnostic uncertainty. Imaging and laboratory investigations eventually led to the diagnosis and she was successfully treated with corticosteroids and rituximab with good response and hearing improvement. This case highlights the importance of early diagnosis in a rapidly progressive disease which undetected can lead to catastrophic end organ damage and disability.

Republished: Improvement of sudden bilateral hearing loss after vertebral artery stenting

2015 ◽  
Vol 8 (3) ◽  
pp. e12-e12 ◽  
Author(s):  
Ji Hwa Kim ◽  
Kyung Jin Roh ◽  
Sang Hyun Suh ◽  
Kyung-Yul Lee
Keyword(s):  
Hearing Loss ◽  
Vertebral Artery ◽  
Posterior Inferior Cerebellar Artery ◽  
Reperfusion Therapy ◽  
Sudden Onset ◽  
Acute Infarction ◽  
Vertebrobasilar Ischemia ◽  
Left Posterior ◽  
Bilateral Sensorineural Hearing Loss ◽  
Bilateral Deafness

Bilateral deafness is a rare but possible symptom of vertebrobasilar ischemia. We report a case of sudden bilateral sensorineural hearing loss caused by bilateral vertebral artery (VA) occlusion which dramatically improved after stenting. A 54-year-old man was admitted with sudden onset of bilateral deafness, vertigo, and drowsy mental status. Brain diffusion-weighted MRI showed acute infarction involving both the posterior inferior cerebellar artery and left posterior cerebral artery territory. Cerebral angiography showed bilateral distal VA occlusion, and emergency intracranial stenting was performed in the left VA. After reperfusion therapy his symptoms gradually improved, including hearing impairment. Endovascular stenting may be helpful in a patient with sudden deafness caused by bilateral VA occlusion.

scholarly journals Sudden Bilateral Deafness in a Patient with Transient Ischemic Attack: A Case Report

2021 ◽  
pp. 119-122
Author(s):  
Caroline Ellinore Pihl ◽  
Christina Fredsby Back ◽  
Helle Klingenberg Iversen ◽  
Faisal Mohammad Amin
Keyword(s):  
Hearing Loss ◽  
Insular Cortex ◽  
Sudden Onset ◽  
Acute Onset ◽  
Motor Deficits ◽  
Ischemic Lesion ◽  
Ischemic Attack ◽  
The Right ◽  
Bilateral Deafness ◽  
Rare Symptom

Sudden-onset bilateral cortical deafness is a very rare symptom of stroke, but must be recognized as stroke, as it is a treatable condition, and the treatment is highly time dependent. We report a 53-year-old man with an acute onset of complete bilateral hearing loss that gradually improved spontaneously over 4 h. The hearing loss was explained by an infarction visualized on magnetic resonance imaging, which showed a subacute temporoparietal ischemic lesion in the left cerebral hemisphere involving the insular cortex and an older infarction in the right temporoparietal region. The location of these kinds of lesions may typically not cause motor deficits, but sensory and cognitive (e.g., aphasia) symptoms, which can be challenging to recognize in a suddenly deaf patient. Taking the possible differential diagnoses into account, immediate stroke workup should always be prioritized in patients with sudden bilateral deafness, as acute revascularizing treatment is possible.

Intramuscular Nerve and Neuromuscular Junction Alteration In Extraocular Muscles of Diabetic Mice

1985 ◽  
Vol 43 ◽  
pp. 682-683
Author(s):  
Bruce R. Pachter
Keyword(s):  
Diabetes Mellitus ◽  
Peripheral Nerves ◽  
Sudden Onset ◽  
Extraocular Muscles ◽  
Diabetic Patients ◽  
Oculomotor Palsy ◽  
Third Nerve Palsy ◽  
Patients With Diabetes ◽  
Intramuscular Nerve ◽  
Oculomotor Nerves

Diabetes mellitus is one of the commonest causes of neuropathy. Diabetic neuropathy is a heterogeneous group of neuropathic disorders to which patients with diabetes mellitus are susceptible; more than one kind of neuropathy can frequently occur in the same individual. Abnormalities are also known to occur in nearly every anatomic subdivision of the eye in diabetic patients. Oculomotor palsy appears to be common in diabetes mellitus for their occurrence in isolation to suggest diabetes. Nerves to the external ocular muscles are most commonly affected, particularly the oculomotor or third cranial nerve. The third nerve palsy of diabetes is characteristic, being of sudden onset, accompanied by orbital and retro-orbital pain, often associated with complete involvement of the external ocular muscles innervated by the nerve. While the human and experimental animal literature is replete with studies on the peripheral nerves in diabetes mellitus, there is but a paucity of reported studies dealing with the oculomotor nerves and their associated extraocular muscles (EOMs).

Lessons Learned From Coaching Postsecondary Students With Traumatic Brain Injury

2020 ◽  
Vol 5 (1) ◽  
pp. 88-96
Author(s):  
Mary R. T. Kennedy
Keyword(s):  
College Students ◽  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Sense Of Self ◽  
Scientific Evidence ◽  
Sudden Onset ◽  
Lessons Learned ◽  
Speech Language Pathologists ◽  
The Brain ◽  
Exhaustive List

Purpose The purpose of this clinical focus article is to provide speech-language pathologists with a brief update of the evidence that provides possible explanations for our experiences while coaching college students with traumatic brain injury (TBI). Method The narrative text provides readers with lessons we learned as speech-language pathologists functioning as cognitive coaches to college students with TBI. This is not meant to be an exhaustive list, but rather to consider the recent scientific evidence that will help our understanding of how best to coach these college students. Conclusion Four lessons are described. Lesson 1 focuses on the value of self-reported responses to surveys, questionnaires, and interviews. Lesson 2 addresses the use of immediate/proximal goals as leverage for students to update their sense of self and how their abilities and disabilities may alter their more distal goals. Lesson 3 reminds us that teamwork is necessary to address the complex issues facing these students, which include their developmental stage, the sudden onset of trauma to the brain, and having to navigate going to college with a TBI. Lesson 4 focuses on the need for college students with TBI to learn how to self-advocate with instructors, family, and peers.

Antiangiogenic gene therapy delays growth of murine and human pancreatic adenocarcinoma in mice

2001 ◽  
Vol 120 (5) ◽  
pp. A349-A349
Author(s):  
J TSENG ◽  
F FARNEBO ◽  
O KISKER ◽  
C BECKER ◽  
C KUO ◽  
...  
Keyword(s):  
Gene Therapy ◽  
Pancreatic Adenocarcinoma ◽  
Human Pancreatic Adenocarcinoma
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