scholarly journals Cognitive impairment and MRI correlates in the elderly patients with type 2 diabetes mellitus

2007 ◽  
Vol 36 (2) ◽  
pp. 164-170 ◽  
Author(s):  
B. van Harten ◽  
J. Oosterman ◽  
D. Muslimovic ◽  
B.-J. P. van Loon ◽  
P. Scheltens ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Cognitive Impairment ◽  
Elderly Patients ◽  
The Elderly

scholarly journals The effect of pharmaceutical care in the elderly patients with type 2 diabetes mellitus

2016 ◽  
Vol 11 (1) ◽  
pp. 93-94 ◽  
Author(s):  
Win Myat Maw ◽  
Mi Mi Saw ◽  
Theingi Kyaw ◽  
Khin Ohnmar Kyaing ◽  
Zaw Min Latt ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Elderly Patients ◽  
Pharmaceutical Care ◽  
The Elderly

Relationship between olfactory dysfunction and cognitive impairment in elderly patients with type 2 diabetes mellitus

2014 ◽  
Vol 106 (3) ◽  
pp. 465-473 ◽  
Author(s):  
Haruna Sanke ◽  
Tomoya Mita ◽  
Hidenori Yoshii ◽  
Ayako Yokota ◽  
Keiko Yamashiro ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Cognitive Impairment ◽  
Elderly Patients ◽  
Olfactory Dysfunction

scholarly journals Type 2 diabetes mellitus in elderly patients treated with endocrinologists in clinical practice

2020 ◽  
Vol 22 (6) ◽  
pp. 582-591
Author(s):  
Elena V. Biryukova
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
High Risk ◽  
Elderly Patients ◽  
Large Scale ◽  
The Elderly ◽  
Modern Medicine ◽  
Aged Patients

A large-scale epidemic of type 2 diabetes mellitus (T2DM) is observed with advanced ageing worldwide. The prevalence of T2DM significantly increases with age. Therefore, this review aimed to summarise the data on T2DM in advanced and older aged patients. The primary geriatric syndromes, which should be considered for the management of older patients (cognitive impairment, sarcopenia, orthostatic hypotension, falls, urinary incontinence, senile asthenia, etc.), are presented. The causes of the high risk for hypoglycaemia in elderly patients are analysed. Improving the treatment for T2DM is a priority of modern medicine. Using antihyperglycaemic therapy is especially difficult in this population due to the high risk of hypoglycaemia and the multi-organ pathology leading to polypharmacy. Therefore, special attention is paid to treatment recommendations. Hypoglycaemic drugs used in elderly patients should be low risk of hypoglycaemia, without nephro- and hepatic toxicity, safe for cardiovascular organs, easy to administer. Furthermore, advantages and limitations of using various groups of hypoglycaemic drugs in elderly patients are discussed. DPP-4 inhibitors are also considered in detail. Modern data on mechanisms of hypoglycaemic action of DPP-4 inhibitors are presented. Possibilities of using sitagliptin in elderly patients were also considered. Finally, evidence-based studies demonstrating the obvious advantages of sitagliptin for the treatment of T2DM in the elderly and advanced aged population are discussed.

scholarly journals Features of Pathogenesis and Course of Type 2 Diabetes Mellitus and Comorbid with it Cardiovascular Pathology in Elderly Patients

2021 ◽  
Vol 6 (3) ◽  
pp. 22-36
Author(s):  
Yu. G. Gorb ◽  
◽  
V. I. Strona ◽  
O. V. Tkachenko ◽  
S. A. Serik ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Heart Failure ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Cognitive Impairment ◽  
Chronic Heart Failure ◽  
Elderly Patients ◽  
Microvascular Complications ◽  
The Body

The features of the pathogenesis and course of type 2 diabetes mellitus and diseases of the cardiovascular system comorbid with it are considered in patients of elderly and old age – coronary artery disease, arterial hypertension, chronic heart failure. The leading role of insulin resistance, hyperglycemia and dyslipidemia in the development of metabolic, homeostatic disorders, the formation of oxidative stress and endothelial dysfunction, which, together with age-related changes in the body, contribute to the progression of type 2 diabetes mellitus and microvascular complications, primarily diabetic cardiomyopathy. Particular attention is paid to the relationship between cognitive impairment, type 2 diabetes mellitus and chronic heart failure. The main factors that worsen the course and prognosis of type 2 diabetes mellitus in elderly patients, in particular, hypertension, atrial fibrillation, diabetic polyneuropathy, nephropathy, and other concomitant diseases, have been identified. Lack of compensation for type 2 diabetes due to metabolic disorders leads to the development of diabetic cardiovascular autonomic neuropathy, diabetic cardiomyopathy along with the progression of atherosclerotic lesions of different localization. The course of type 2 diabetes in these patients is often complicated by geriatric syndrome, which contains a set of cognitive impairment, senile weakness, depression, functional disorders, polymorbidity. Cognitive disorders negatively affect the course of type 2 diabetes and its complications, significantly disrupting the process of teaching patients the methods of self-control, following the advice of a doctor. It is noted that the management of this category of patients should be individual and include adequate correction of hyperglycemia to prevent microvascular complications and hypoglycemic conditions, as well as reduce cardiovascular mortality and maintain quality of life. Rational selection of drugs, taking into account the factors that determine their impact on the body of elderly patients with type 2 diabetes mellitus and possible adverse drug reactions, will increase the effectiveness and safety of drug therapy in such patients. Optimizing therapeutic approaches for elderly patients with type 2 diabetes requires effective changes in the health care system to provide them with comprehensive medical and social care according to their special needs

scholarly journals The Epidemiology of Cognitive impairment in elderly patients with type 2 diabetes mellitus: prevalence and related clinical factors

2021 ◽  
pp. 259
Author(s):  
A. V. Balashova ◽  
I. V. Glinkina ◽  
V. V. Fadeev
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Cognitive Impairment ◽  
Elderly Patients ◽  
Clinical Factors

Цель: оценить распространенность когнитивных нарушений (КН) у пожилых пациентов с сахарным диабетом (СД) 2 типа.

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