scholarly journals Cholesterol and long-term mortality after acute myocardial infarction in elderly patients

1999 ◽  
Vol 28 (3) ◽  
pp. 313-315 ◽  
Author(s):  
M Bo
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Elderly Patients ◽  
Long Term Mortality

scholarly journals Impact of Malnutrition on Long-Term Mortality in Elderly Patients with Acute Myocardial Infarction

Nutrients ◽  
2019 ◽  
Vol 11 (2) ◽  
pp. 224 ◽  
Author(s):  
Klara Komici ◽  
Dino Vitale ◽  
Angela Mancini ◽  
Leonardo Bencivenga ◽  
Maddalena Conte ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Nutritional Status ◽  
Elderly Patients ◽  
Troponin I ◽  
Nutritional Assessment ◽  
Mini Nutritional Assessment ◽  
Grace Score ◽  
Long Term Mortality

Background: Malnutrition is a frequent condition in the elderly, and is associated with prolonged hospitalization and increased mortality. However, the impacts of malnutrition among elderly patients with acute myocardial infarction have not been clarified yet. Methods and Results: We enrolled 174 patients aged 65 years and over, admitted with the diagnosis of acute myocardial infarction (AMI), who underwent evaluation of nutritional status by Mini Nutritional Assessment (MNA) and evaluation of mortality risk by GRACE Score 2.0. All-cause mortality was the outcome considered for this study. Over a mean follow-up of 24.5 ± 18.2 months, 43 deaths have been registered (24.3%). Non-survivors were more likely to be older, with worse glomerular filtration rate, lower systolic blood pressure, lower albumin and MNA score, higher prevalence of Killip classification III-IV grade, and higher Troponin I levels. Multivariate Cox proportional analysis revealed that GRACE Score and MNA showed a significant and independent impact on mortality, (HR = 1.76, 95%, CI = 1.34–2.32, and HR = 0.56, 95% CI = 0.42–0.73, respectively). Moreover, the clinical decision curve revealed a higher clinical net benefit when the MNA was included, compared to the partial models without MNA. Conclusion: Nutritional status is an independent predictor of long-term mortality among elderly patients with AMI. MNA score in elderly patients with AMI may help prognostic stratification and identification of patients with, or at risk of, malnutrition in order to apply interventions to improve nutritional status, and maybe survival in this population.

scholarly journals Impact of Malnutrition on Long-Term Mortality in Elderly Patients with Acute Myocardial Infarction

2018 ◽  
Author(s):  
Klara Komici ◽  
Dino Franco Vitale ◽  
Angela Mancini ◽  
Leonardo Bencivenga ◽  
Maddalena Conte ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Nutritional Status ◽  
Elderly Patients ◽  
Troponin I ◽  
Mini Nutritional Assessment ◽  
The Impact ◽  
Grace Score ◽  
Long Term Mortality

Background: Malnutrition is a frequent condition in the elderly and is associated with prolonged hospitalization and increased mortality. However, the impact of malnutrition among elderly patients with acute myocardial infarction has not been clarified yet. Methods and Results: We have enrolled 174 patients aged 65 years and over, admitted with the diagnosis of acute myocardial infarction (AMI) who underwent to the evaluation of nutritional status by Mini Nutritional Assessment (MNA) and of mortality risk by Grace score 2.0. All-cause mortality was the outcome considered for this study. Over a mean follow-up of 24.5 ± 18.2 months, 43 deaths have been registered (24.3%). Non-survivors were more likely to be older, with worse GFR, lower SBP, lower albumin and MNA score, higher prevalence of Killip classification III-IV grade, and higher Troponin I levels. Multivariate Cox proportional analysis revealed that Grace score and MNA showed a significant and independent impact on mortality, (HR = 1.76, 95% CI = 1.34–2.32 and HR = 0.56, 95% CI = 0.42–0.73, respectively). Moreover, the clinical decision curve revealed a higher clinical net benefit when the MNA was included compared to the partial models without MNA. Conclusions: Nutritional status is an independent predictor of long-term mortality among elderly patients with AMI. MNA score in elderly patients with AMI may help prognostic stratification and identification of patients with/at risk of malnutrition in order to apply interventions to improve nutritional status and maybe survival in this population.

scholarly journals Role of diuretics on long-term mortality may differ in volume status in patients with acute myocardial infarction

2020 ◽  
Vol 41 (Supplement_2) ◽  
Author(s):  
T Kawai ◽  
D Nakatani ◽  
T Yamada ◽  
T Watanabe ◽  
T Morita ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Propensity Score ◽  
Plasma Volume ◽  
Cox Regression ◽  
Volume Status ◽  
Increased Risk ◽  
Long Term Mortality

Abstract Background Diuretics has been reported to have a potential for an activation of the renin-angiotensin-aldosterone system and the sympathetic nervous system, leading to a possibility of poor clinical outcome in patients with cardiovascular disease. However, few data are available on clinical impact of diuretics on long-term outcome in patients with acute myocardial infarction (AMI) based on plasma volume status. Methods To address the issue, a total of 3,416 survived patients with AMI who were registered to a large database of the Osaka Acute Coronary Insufficiency Study (OACIS) were studied. Plasma volume status was assessed with the estimated plasma volume status (ePVS) that was calculated at discharge as follows: actual PV = (1 − hematocrit) × [a + (b × body weight)] (a=1530 in males and a=864 in females, b=41.0 in males and b=47.9 in females); ideal PV = c × body weight (c=39 in males and c=40 in females), and ePVS = [(actual PV − ideal PV)/ideal PV] × 100 (%). Multivariable Cox regression analysis and propensity score matching were performed to account for imbalances in covariates. The endpoint was all-cause of death (ACD) within 5 years. Results During a median follow-up period of 855±656 days, 193 patients had ACD. In whole population, there was no significant difference in long-term mortality risk between patients with and without diuretics in both multivariate cox regression model and propensity score matching population. When patients were divided into 2 groups according to ePVS with a median value of 4.2%, 46 and 147 patients had ACD in groups with low ePVS and high ePVS, respectively. Multivariate Cox analysis showed that use of diuretics was independently associated with an increased risk of ACD in low ePVS group, (HR: 2.63, 95% confidence interval [CI]: 1.22–5.63, p=0.01), but not in high ePVS group (HR: 0.70, 95% CI: 0.44–1.10, p=0.12). These observations were consistent in the propensity-score matched cohorts; the 5-year mortality rate was significantly higher in patients with diuretics than those without among low ePVS group (4.7% vs 1.7%, p=0.041), but not among high ePVS group (8.0% vs 10.3%, p=0.247). Conclusion Prescription of diuretics at discharge was associated with increased risk of 5-year mortality in patients with AMI without PV expansion, but not with PV expansion. The role of diuretics on long-term mortality may differ in plasma volume status. Therefore, prescription of diuretics after AMI may be considered based on plasma volume status. Funding Acknowledgement Type of funding source: None

scholarly journals Long-term mortality following interhospital transfer for acute myocardial infarction

Heart ◽  
2015 ◽  
Vol 101 (13) ◽  
pp. 1032-1040 ◽  
Author(s):  
Isuru Ranasinghe ◽  
Federica Barzi ◽  
David Brieger ◽  
Martin Gallagher
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Interhospital Transfer ◽  
Long Term Mortality

scholarly journals Short- and long-term mortality for patients undergoing primary angioplasty for acute myocardial infarction

2000 ◽  
Vol 36 (4) ◽  
pp. 1194-1201 ◽  
Author(s):  
Edward L Hannan ◽  
Michael J Racz ◽  
Djavad T Arani ◽  
Thomas J Ryan ◽  
Gary Walford ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Primary Angioplasty ◽  
Short And Long Term ◽  
Long Term Mortality

Mild Depression Predicts Long-Term Mortality After Acute Myocardial Infarction: A 25-Year Follow-Up

2019 ◽  
Vol 28 (12) ◽  
pp. 1812-1818 ◽  
Author(s):  
Marian U. Worcester ◽  
Alan J. Goble ◽  
Peter C. Elliott ◽  
Erika S. Froelicher ◽  
Barbara M. Murphy ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Mild Depression ◽  
Long Term Mortality

scholarly journals Short- and long-term mortality after acute myocardial infarction: comparison of patients with and without diabetes mellitus

2007 ◽  
Vol 22 (12) ◽  
pp. 883-888 ◽  
Author(s):  
H. L. Koek ◽  
S. S. Soedamah-Muthu ◽  
J. W. P. F. Kardaun ◽  
E. Gevers ◽  
A. de Bruin ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Short And Long Term ◽  
Long Term Mortality
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