scholarly journals Milk and Dairy Product Consumption and Prostate Cancer Risk and Mortality: An Overview of Systematic Reviews and Meta-analyses

2019 ◽  
Vol 10 (suppl_2) ◽  
pp. S212-S223 ◽  
Author(s):  
Bricia López-Plaza ◽  
Laura M Bermejo ◽  
Cristina Santurino ◽  
Iván Cavero-Redondo ◽  
Celia Álvarez-Bueno ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cancer Risk ◽  
Systematic Reviews ◽  
Dairy Product ◽  
Prostate Cancer Risk ◽  
Product Consumption ◽  
Overview Of Systematic Reviews ◽  
Meta Analyses ◽  
Dairy Product Consumption

scholarly journals Milk and Dairy Product Consumption and Risk of Mortality: An Overview of Systematic Reviews and Meta-Analyses

2019 ◽  
Vol 10 (suppl_2) ◽  
pp. S97-S104 ◽  
Author(s):  
Ivan Cavero-Redondo ◽  
Celia Alvarez-Bueno ◽  
Mercedes Sotos-Prieto ◽  
Angel Gil ◽  
Vicente Martinez-Vizcaino ◽  
...  
Keyword(s):  
Systematic Reviews ◽  
Dairy Product ◽  
Product Consumption ◽  
Risk Of Mortality ◽  
Overview Of Systematic Reviews ◽  
Meta Analyses ◽  
Dairy Product Consumption

scholarly journals Dairy Product Consumption and Prostate Cancer Risk in the United States

Nutrients ◽  
2019 ◽  
Vol 11 (7) ◽  
pp. 1615 ◽  
Author(s):  
Isabella Preble ◽  
Zhenzhen Zhang ◽  
Ryan Kopp ◽  
Mark Garzotto ◽  
Gerd Bobe ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
United States ◽  
Cancer Risk ◽  
Dairy Products ◽  
Dairy Product ◽  
Prostate Cancer Risk ◽  
The United States ◽  
Product Consumption ◽  
Dairy Consumption ◽  
Dairy Product Consumption

An ongoing controversy exists regarding the effect of dairy products on prostate cancer risk in observational studies. We prospectively investigated the associations between dairy product consumption and prostate cancer risk among men in the United States. After calculating pre-diagnostic intake of individual or subgroups of dairy products using a validated food frequency questionnaire, we estimated hazard ratios (HR) and 95% confidence intervals (CI) for pathologically-verified cases of incident prostate cancer among men, overall, or stratified by severity. Among 49,472 men, 4134 were diagnosed with prostate cancer during an average follow-up period of 11.2 years. The median total dairy intake was 101 g/1000 kcal. Consumption of total, individual, or subgroups of dairy products was not statistically significantly associated with prostate cancer risk overall (HR = 1.05, 95% CI = 0.96–1.15 comparing the highest with lowest quartile) or stratified by severity, except for regular-fat dairy product intake with late-stage prostate cancer risk (HR = 1.37, 95% CI = 1.04–1.82 comparing the highest with lowest quartile) and 2%-fat milk intake with advanced prostate cancer risk (HR = 1.14, 95% CI = 1.02–1.28 comparing the higher than median intake with no intake group). Our findings do not support the previously reported harmful impact of dairy consumption on overall prostate cancer risk among men in the United States.

scholarly journals Effects of Milk and Dairy Product Consumption on Type 2 Diabetes: Overview of Systematic Reviews and Meta-Analyses

2019 ◽  
Vol 10 (suppl_2) ◽  
pp. S154-S163 ◽  
Author(s):  
Celia Alvarez-Bueno ◽  
Ivan Cavero-Redondo ◽  
Vicente Martinez-Vizcaino ◽  
Mercedes Sotos-Prieto ◽  
Jonatan R Ruiz ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Systematic Reviews ◽  
Dairy Product ◽  
Product Consumption ◽  
Overview Of Systematic Reviews ◽  
Meta Analyses ◽  
Dairy Product Consumption

scholarly journals Dairy Product Consumption and Prostate Cancer Risk in the US (P05-034-19)

2019 ◽  
Vol 3 (Supplement_1) ◽  
Author(s):  
Isabella Preble ◽  
Zhenzhen Zhang ◽  
Ryan Kopp ◽  
Mark Garzotto ◽  
Gerd Bobe ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cancer Risk ◽  
Late Stage ◽  
Dairy Product ◽  
Prostate Cancer Risk ◽  
Positive Association ◽  
High Fat ◽  
Dairy Intake ◽  
Product Consumption ◽  
Dairy Product Consumption

Abstract Objectives We prospectively investigated the association between dairy product intake and prostate cancer risk among men in the Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial (PLCO) cohort. Methods Pre-diagnostic dairy product intake was assessed using a validated food frequency questionnaire. Incident prostate cancer was ascertained by study visits, local cancer registries, or self-reports and only pathologically-verified cases were included in the analysis. In addition to overall prostate cancer, we classified cases by severity (early vs late stage, or low vs high Gleason scores). Using multivariate Cox regression models, we estimated hazard ratios (HR) and 95% confidence intervals (CI) for associations of prostate cancer risk with dairy product intake, as total (all dairy products), by fat content (low- or high-fat), or by fermentation methods (fermented or non-fermented). Results Among 49,472 men, 4134 were diagnosed with prostate cancer during an average follow-up period of 11.2 years. The median total dairy product intake was 101 g/1000 Kcal. Total dairy product consumption was not statistically significantly associated with risk of any prostate cancer or stratified by disease severity. The HR (95% CI) comparing the highest with the lowest quartiles of total dairy product intake was 1.05 (0.96–1.15) for overall prostate cancer risk and ranged from 1.00 (0.88–1.14), for risk of prostate cancer with high-Gleason score, to 1.24 (0.93–1.66), for risk of late-stage prostate cancer. The only statistically significant finding in our stratified analyses was a positive association between high-fat dairy product intake and late-stage prostate cancer risk (HR = 1.37, 95% CI = 1.04–1.82, P-trend = 0.02). However, associations with high-fat dairy intake did not differ by stage (P = 0.15), suggesting a chance finding for the positive association with late-stage prostate cancer. Conclusions These preliminary findings do not support the previously-reported harmful impact of dairy product consumption on prostate cancer risk among US men. The observed association of high-fat dairy intake with late-stage prostate cancer needs to be confirmed in other studies. Funding Sources This study was funded by the Oregon Health & Science University/Oregon State University Cancer Prevention and Control Initiative.

scholarly journals Milk and Dairy Product Consumption and Cardiovascular Diseases: An Overview of Systematic Reviews and Meta-Analyses

2019 ◽  
Vol 10 (suppl_2) ◽  
pp. S164-S189 ◽  
Author(s):  
Javier Fontecha ◽  
Maria Visitación Calvo ◽  
Manuela Juarez ◽  
Angel Gil ◽  
Vicente Martínez-Vizcaino
Keyword(s):  
Cardiovascular Diseases ◽  
Systematic Reviews ◽  
Dairy Product ◽  
Product Consumption ◽  
Overview Of Systematic Reviews ◽  
Meta Analyses ◽  
Dairy Product Consumption

scholarly journals Dairy product consumption and development of cancer: an overview of reviews

BMJ Open ◽  
2019 ◽  
Vol 9 (1) ◽  
pp. e023625 ◽  
Author(s):  
Maya M Jeyaraman ◽  
Ahmed M Abou-Setta ◽  
Laurel Grant ◽  
Farnaz Farshidfar ◽  
Leslie Copstein ◽  
...  
Keyword(s):  
Systematic Reviews ◽  
Dairy Product ◽  
Overview Of Reviews ◽  
Product Consumption ◽  
Dairy Consumption ◽  
Cancer Specific Mortality ◽  
Meta Analyses ◽  
Study Designs ◽  
Dairy Product Consumption

ObjectivesTo provide a comprehensive systematic overview of current evidence from pooled analyses/meta-analyses and systematic reviews (PMASRs) pertaining to dairy consumption and incident cancer and/or all-cause or cancer-specific mortality.DesignOverview of reviews.SettingCommunity setting.ParticipantsThe unit of analysis is PMASRs. A total of 42 PMASRs was included in this overview of reviews.Interventions/exposuresAny dairy product consumption (eg, milk, yogurt, etc).Primary and secondary outcomes measuresPrimary outcome measure is development of any type of cancer. Secondary outcome measures are all-cause mortality and cancer-specific mortality.ResultsFrom 9693 citations identified, we included 42 PMASRs (52 study reports) published between 1991 and 2017. Thirty-one (74%) of these was pooled analyses/meta analyses, and only 11 (26%) were systematic reviews and meta-analyses. There was a wide variability in the type of study designs included within the other PMASRs, thus contributing to variable and, in instances, divergent estimates of cancer risk for several cancer subtypes. For example, only one systematic review and meta-analysis exclusively included prospective study designs. Most PMASRs were of low to moderate quality based on the Assessing the Methodological Quality of Systematic Reviews (AMSTAR) scores. The median AMSTAR score was 5 (IQR 2–7). Our overview identified conflicting evidence from PMASRs on association between dairy consumption and incident cancers or mortality. Heterogeneity in summary estimates reflected the inclusion of variable study designs and overall low methodological quality of individual PMASRs.ConclusionsThe association between dairy consumption and cancer risk has been explored in PMASRs with a variety of study designs and of low to moderate quality. To fully characterise valid associations between dairy consumption and risk of cancer and/or mortality rigorously conducted, PMASRs including only high-quality prospective study designs are required.Trial registration numberCRD42017078463.

scholarly journals Milk and Dairy Product Consumption and Bladder Cancer Risk: A Systematic Review and Meta-Analysis of Observational Studies

2019 ◽  
Vol 10 (suppl_2) ◽  
pp. S224-S238 ◽  
Author(s):  
Laura M Bermejo ◽  
Bricia López-Plaza ◽  
Cristina Santurino ◽  
Iván Cavero-Redondo ◽  
Carmen Gómez-Candela
Keyword(s):  
Systematic Review ◽  
Bladder Cancer ◽  
Cancer Risk ◽  
Observational Studies ◽  
Meta Analysis ◽  
Dairy Product ◽  
Bladder Cancer Risk ◽  
Product Consumption ◽  
Dairy Product Consumption

Dairy Product Consumption and Bladder Cancer Risk: A Meta-Analysis

2019 ◽  
Vol 72 (3) ◽  
pp. 377-385 ◽  
Author(s):  
Jianhua Wu ◽  
Yi Yu ◽  
Liqi Huang ◽  
Zirui Li ◽  
Penghui Guo ◽  
...  
Keyword(s):  
Bladder Cancer ◽  
Cancer Risk ◽  
Meta Analysis ◽  
Dairy Product ◽  
Bladder Cancer Risk ◽  
Product Consumption ◽  
Dairy Product Consumption

scholarly journals A Review of the Role of Milk and Dairy Products in the Development of Obesity and Cardiometabolic Disease

2020 ◽  
Vol 4 (Supplement_2) ◽  
pp. 1629-1629
Author(s):  
Anestis Dougkas ◽  
Ditte Hobbs
Keyword(s):  
Dairy Products ◽  
Dairy Product ◽  
Fat Content ◽  
Product Consumption ◽  
Meta Analyses ◽  
Dairy Milk ◽  
Dairy Product Consumption ◽  
Milk And Dairy Products

Abstract Objectives The consumption of milk and dairy products makes an important contribution to children's nutrient intake, yet due to relatively high saturated fat content, the health benefits of dairy products have come under question and public health advice is often perceived as unclear. This review aimed to provide an overview of the current available evidence taken from systematic reviews and meta-analyses on dairy product consumption and risk of obesity, type 2 diabetes (T2D) and cardiovascular disease (CVD) in children, adolescents, and adults. Methods The literature of English-language systematic reviews and meta-analyses published up to September 2019 was reviewed by searching the following three databases: ISI Web of Science, PubMed, and Google Scholar. Search terms included ‘dairy’, ‘milk’, ‘yogurt’, ‘obesity’, ‘adiposity’, ‘bodyweight’, ‘type 2 diabetes’, ‘cardiovascular diseases’, ‘coronary heart disease’, ‘blood pressure’, ‘insulin resistance’, ‘glucose’, ‘children’, ‘adolescents’, ‘adults’ and combinations of these. Published work on calcium supplementation was excluded. Results Milk and certain dairy products were found to be not associated with or inversely associated with obesity in children and adolescents. In adults, consumption of milk and dairy products improves body composition and enhances weight loss during energy restriction diets, while it has a neutral effect on body weight in maintenance diets. Prospective cohort studies suggest that the consumption of dairy products, with regular or low-fat content, does not adversely affect the risk of T2D or CVD outcomes and may have a protective effect. The plausible mechanisms underlying the effect of dairy nutrients on obesity and cardiometabolic disease are incompletely understood but may include effects on lipolysis, lipogenesis and fatty acid absorption. Conclusions Dairy product consumption, as part of a balanced diet, may protect against the risk of obesity, T2D, and CVD. However, further research is needed to better understand the role of different types of dairy products and of different fat content in obesity, T2D, and CVD. The new and emerging range of products (including plant-based alternatives) being used as dairy milk substitutes has yet to be evaluated in scientific studies. Funding Sources None.

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