scholarly journals Comorbidity, Functional Impairment, and Emotional Distress: A Coping Mediation Model for Persons With Cancer

Author(s):  
Thomas V Merluzzi ◽  
Errol J Philip ◽  
Brenna Gomer ◽  
Carolyn A Heitzmann Ruhf ◽  
Dahyeon Kim

Abstract Background Comorbid disease in cancer patients can substantially impact medical care, emotional distress, and mortality. However, there is a paucity of research on how coping may affect the relationship between comorbidity and emotional distress. Purpose The current study investigated whether the relations between comorbidity and emotional distress and between functional impairment and emotional distress were mediated by three types of coping: action planning (AP), support/advice seeking (SAS), and disengagement (DD). Methods Four hundred and eighty-three persons with cancer completed a measure of functional impairment (Sickness Impact Profile), the Checklist of Comorbid Conditions, the Brief COPE, the Hospital Anxiety and Depression Scale, the Quality of Life Assessment for Cancer Survivors (Negative Feelings Scale), and the Distress Screening Schedule (Emotional Distress Scale). The latter three measures were used to form a latent construct representing the outcome, emotional distress. Results Model comparison analysis indicated that the model with DD as a mediator had a better fit than models containing AP and SAS. DD mediated the relationship between functional impairment and emotional distress, so that engaging in DD was associated with greater distress. In addition, comorbidity and functional impairment were directly and positively related to emotional distress, but the relation between comorbidity and distress was not mediated by coping type. Conclusions Both comorbidity and functional impairment may be associated with distress, but disengagement coping only mediated the relation involving functional impairment and was positively associated with distress. Future studies can investigate whether teaching active coping or adaptive coping (e.g., through mindfulness exercises) can decrease distress in cancer patients, despite functional impairments.

2021 ◽  
Vol 12 ◽  
Author(s):  
Patricia Toquero ◽  
Carmen Blanco Fernández ◽  
María Pilar López Martí ◽  
Berta Hernández Marín ◽  
E. Beatriz Vera Cea ◽  
...  

Background: The COVID-19 pandemic has caused mental health problems worldwide. The psychopathological implications of COVID-19 in cancer patients have rarely been addressed. Considering the increased vulnerability of oncology patients, this issue needs to be addressed to improve the long-term mental health status of these patients.Methods: We conducted a prospective study in outpatients under active cancer treatment during the first wave of the COVID-19 pandemic. A semi-structured 24-question survey was designed to measure baseline sociodemographic, psychosocial and COVID-19 exposure characteristics. The Hospital Anxiety and Depression Scale was used to measure psychological symptoms. A descriptive and analytical univariate analysis of the variables studied was performed. We used the Z-score to compare different populations (experimental and historical control cohort).Results: 104 patients were included, the majority of which were women (64.4%), were above 65 years of age (57.7%), had either lung and breast cancer (56.7%), had advanced disease (64%) and were undergoing chemotherapy (63.5%). 51% of them expressed greater fear of cancer than of COVID-19 infection or both.In relation to HADS, 52.8% of emotional distress, 42.3% of anxiety and 58.6% of depression rates were detected. The main factors related with higher rates of psychological symptomatology were history of previous psychotropic drug consumption and the adoption of additional infection prevention measures because they considered themselves at risk of severe COVID-19 infection (p = 0.008; p = 0.003 for emotional distress, p = 0.026; p = 0.004 for anxiety, and p = 0.013; p = 0.008 for depression). Tumor type, stage, oncologic treatment or rescheduling of cancer treatments were not related to higher levels of psychological symptomatology.Comparison of our results with another population of similar characteristics was not significant (Z score = −1.88; p = 0.060).Conclusions: We detected high rates of emotional distress during the first wave of the COVID-19 pandemic among cancer patients in active treatment (52.8%). This was higher and clinically relevant than observed in a comparable population (42.5%), although not significant. Cancer itself is the main factor of concern for cancer patients, above and beyond the emotional distress generated by COVID-19 pandemic.


2007 ◽  
Vol 25 (22) ◽  
pp. 3313-3320 ◽  
Author(s):  
Stephan Gripp ◽  
Sibylle Moeller ◽  
Edwin Bölke ◽  
Gerd Schmitt ◽  
Christiane Matuschek ◽  
...  

Purpose To study how survival of palliative cancer patients relates to subjective prediction of survival, objective prognostic factors (PFs), and individual psychological coping. Patients and Methods Survival was estimated according to three categories (< 1 month, 1 to 6 months, and > 6 months) by two physicians (A and B) and the institutional tumor board (C) for 216 patients recently referred for palliative radiotherapy. After 6 months, the accuracy of these estimates was assessed. The prognostic relevance of clinical symptoms, performance status, laboratory tests, and self-reported emotional distress (Hospital Anxiety and Depression Scale) was investigated. Results In 61%, 55%, and 63% of the patients, prognoses were correctly estimated by A, B, and C, respectively. κ statistic showed fair agreement of the estimates, which proved to be overly optimistic. Accuracy of the three estimates did not improve with increasing professional experience. In particular, the survival of 96%, 71%, and 87% of patients who died in less than 1 month was overestimated by A, B, and C, respectively. On univariate analysis, 11 of 27 parameters significantly affected survival, namely performance status, primary cancer, fatigue, dyspnea, use of strong analgesics, brain metastases, leukocytosis, lactate dehydrogenase (LDH), depression, and anxiety. On multivariate analysis, colorectal and breast cancer had a favorable prognosis, whereas brain metastases, Karnofsky performance status less than 50%, strong analgesics, dyspnea, LDH, and leukocytosis were associated with a poor prognosis. Conclusion This study revealed that physicians' survival estimates were unreliable, especially in the case of patients near death. Self-reported emotional distress and objective PFs may improve the accuracy of survival estimates.


2021 ◽  
Vol 3 (3) ◽  
pp. 297-304
Author(s):  
Dwi Retnaningsih ◽  
Roudhotul Auliyak ◽  
Mariyati Mariyati ◽  
Enggar Nurnaningsih

Depression in breast cancer patients includes mental shock, inability to accept reality, hopelessness, fear of death, and fear of the future. Depression creates long periods of sadness and worry, usually accompanied by feelings of worthlessness. Fatigue is a symptom that often appears in cancer patients undergoing chemotherapy. Associated with the conditions of the COVID-19 pandemic, cancer patients have an increased risk of transmitting COVID-19 because they have decreased endurance. This study aims to determine the relationship between depression and fatigue in breast cancer patients undergoing chemotherapy at Hospital Sultan Agung Semarang Indonesia. The instruments used in this study were questionnaire of the hospitals anxiety and Depression Scale (HADS) and questionnaire of fatigue, 30 female respondents who suffer from breast cancer and have undergone chemotherapy. Rank Spearman data analysis. P value = 0.000 and correlation coefficient value r = 0.671. There is a relationship between depression and fatigue in breast cancer patients undergoing chemotherapy which has an impact on adherence to chemotherapy for breast cancer patients. The higher the level of depression is, the more severe the level of fatigue in cancer patients.


2009 ◽  
Vol 24 (7) ◽  
pp. 470-475 ◽  
Author(s):  
F.-W. Lung ◽  
B.-C. Shu ◽  
P.-F. Chen

AbstractPersonality has been proposed as having a possible effect on the reaction that patients have toward auditory hallucination. However, this factor has not been studied previously. Thus, this study investigated the relationship among demographics, personality, cognition and emotional response in schizophrenics with persistent auditory hallucination. One-hundred and fourteen subjects with persistent auditory hallucination completed the Eysenck Personality Questionnaire, the revised Beliefs about Voices Questionnaire and the Chinese-version Hospital Anxiety and Depression Scale. Structural equation model showed that personality had an effect on beliefs about the hallucination (malevolent or benevolent), which then affected the reaction of patients toward these voices (engages or resists). Their reaction will further affect the anxious or depressed state of the patients. When these hallucinations were categorized into the three levels of omnipotence, beliefs and reactions, the model was more significant than that of one-level model. Persistent auditory hallucination only accounted for a portion of the emotional distress when malevolent or benevolent voices were perceived, and personality characteristics accounted for the remaining emotional distress in schizophrenics. This model helped us understand the relationship between personality, cognition and affective symptoms, such that, when therapists decide what “trait” to change, they can determine at which point to intervene.


2003 ◽  
Vol 1 (2) ◽  
pp. 143-151 ◽  
Author(s):  
ALICE INMAN ◽  
KENNETH L. KIRSH ◽  
STEVEN D. PASSIK

Objective: Spirituality has been neglected when assessing the well-being of cancer patients. Traditionally, researchers have focused on areas such as physical, social, and emotional functioning. However, there is a potential for spirituality to have a large impact on quality of life in patients with cancer. The current study was conducted to investigate the relationship between spirituality and boredom, constraint, social contact, and depression.Methods: A total of 100 oncology patients completed several assessment instruments, including the Purposelessness, Under-stimulation, and Boredom (PUB) Scale, Functional Assessment of Cancer Therapy Scale–Anemia, Brief Zung Self-Rating Depression Scale (BZSDS), Cancer Behavior Inventory, Systems of Belief Inventory, and Eastern Cooperative Oncology Group Performance Status Scale.Results: The average age of the sample was 62.37 years (SD = 13.43) and was comprised of 60 women (60%) and 40 men (40%). A regression analysis conducted to explore the impact of the variables on quality of life found only the BZSDS (R2Δ = .650, F = 180.392, p < .001) and the PUB Scale (R2Δ = .077, F = 26.885, p < .001) were significant predictors of quality of life. Another set of regression analyses were conducted to explore whether spirituality had a mediating effect on this relationship, but the mediated model was not supported.Significance of results: We conclude that spirituality and boredom are difficult concepts to define, operationalize, and measure, but crucial to our understanding of quality of life in advanced cancer. More research is needed to clarify the nature of the interrelationships between these important concepts.


2020 ◽  
Author(s):  
Tenzin Yangchen

UNSTRUCTURED Given the high incidence of mental disorders in populations exposed to traumatic events and ensuing detrimental consequences, it is apparent that a better understanding of the role of coping styles in resilience and distress is of paramount importance. The proposed mixed-methods exploratory study will present an empirical framework for the research by examining the relationship between resilience, coping styles (i.e., problem-focused, meaning-focused, and the two strategies of emotion-focused coping) and psychological distress. Further, this study aims to explore the moderating effects of different coping styles on the relationship between resilience and psychological distress. Seventy-five Tibetans currently residing in New York will be recruited for this study. An online battery of validated questionnaires comprising the Kessler Psychological Distress Scale (K10), Brief COPE, and Connor-Davidson Resilience Scale (CD-RISC) will be administered via Qualtrics survey software to assess distress, coping styles, and resilience, respectively. Additionally, qualitative interviews will be conducted to explore the participants’ understandings of distress and resilience as well as to gain a fuller understanding of their utilization of coping styles. Based on the theoretical conceptualization of stress and coping, it is hypothesized that people who score high on problem-focused, meaning-focused, and emotion-focused (emotional support-seeking) coping will report higher resilience and lower levels of psychological distress. The researcher also hypothesizes that participants who identify emotion-focused coping (escapism-avoidance) as their primary coping style will report lower resilience and higher concurrent psychological distress. Path analysis with a series of multiple regression analyses will be used to evaluate the plausibility of those theoretical hypotheses.


2008 ◽  
Vol 26 (29) ◽  
pp. 4725-4730 ◽  
Author(s):  
Jane Walker ◽  
Rachel A. Waters ◽  
Gordon Murray ◽  
Helen Swanson ◽  
Carina J. Hibberd ◽  
...  

Purpose Cancer is associated with an increased risk of suicide and attempted suicide. However, we do not know how many cancer patients have thoughts that they would be better off dead or thoughts of hurting themselves. This study aimed to determine the prevalence of such thoughts in cancer outpatients and which patients are most likely to have them. Patients and Methods A survey of consecutive patients who attended the outpatient clinics of a regional cancer center in Edinburgh, United Kingdom. Patients completed the Patient Health Questionnaire-9 (PHQ-9), which included Item 9 that asks patients if they have had thoughts of being better off dead or of hurting themselves in some way in the previous 2 weeks. Those who reported having had such thoughts for at least several days in this period were labeled as positive responders. Patients also completed the Hospital Anxiety and Depression Scale (HADS) and a pain scale. The participating patients’ cancer diagnoses and treatments were obtained from the cancer center clinical database. Results Data were available on 2,924 patients; 7.8% (229 of 2,924; 95% CI, 6.9% to 8.9%) were positive responders. Clinically significant emotional distress, substantial pain, and—to a lesser extent—older age, were associated with a positive response. There was strong evidence of interactions between these effects, and emotional distress played the most important role. Conclusion A substantial number of cancer outpatients report thoughts that they would be better off dead or thoughts of hurting themselves. Management of emotional distress and pain should be a central aspect of cancer care.


2021 ◽  
Author(s):  
Mohammad Ali Hossein Tehrani ◽  
Mohammad Hadi Yadollahpour ◽  
Mohsen Vakili Sadeghi ◽  
Angela Hamidia

Abstract Purpose: Spiritual health is one of the dimensions of health associated with physical, social, and mental health. It can play an essential role in coping with stressful disease-related conditions. The purpose of this study was to evaluate the association between spiritual health and the level of anxiety and depression among cancer patients. Methods: In this cross-sectional study, 200 cancer patients were referred to a tertiary hospital in Iran. Hospital Anxiety and Depression Scale (HADS) and Spiritual Well Being Scale questionnaires were provided to the patients. Results: The mean score of spiritual health was 76.61±20.007 in cancer patients, which was considered moderate. The relationship between spiritual health and anxiety and between spiritual health and depression was significant. According to the Pearson correlation coefficient, the relationship between spiritual health and anxiety (r=-0.838) and depression (r=-0.834) was inverse. Furthermore, the relationship between spiritual health and anxiety (P<0.001) (r=-0.832) and depression (P<0.001) (r=-0.842) and the relationship between existential health and anxiety (P<0.001) (r=-0.830) and depression (P<0.001) (r=-0.813) were significant and inverse. Conclusion: The present study showed that spiritual health positively reduces anxiety and depression in cancer patients, promotes mental health, and accelerates and improves the disease.


2021 ◽  
Vol 19 (1) ◽  
Author(s):  
Karol Konaszewski ◽  
Małgorzata Niesiobędzka ◽  
Janusz Surzykiewicz

Abstract Background Mental health is an important aspect of the process of individual adaptation and development. The present study analysed the role played by resilience in mental health while taking into account both positive and negative indicators among juveniles. The aim of the first study (Study 1) is to analyse the relationship between resilience and the broadly understood mental health of juveniles admitted to youth education centres. Study 2 aimed to understand the direct and indirect role of resilience in shaping the mental health of juveniles. In the model we tested, we looked at the relationship among resilience, coping strategies, and mental well-being. Methods The first study involved 201 juveniles, and the second involved 253 juveniles. Resilience was measured by the Resilience Scale-14. Coping strategies were measured with the Brief-COPE Questionnaire, and information on mental health was obtained using the Kutcher Adolescent Depression Scale, the Satisfaction with Life Scale and the Warwick-Edinburgh Mental Well-being Scale. Results The results of both studies have shown that resilience is an important predictor of the mental health of juveniles, primarily with respect to its positive indicator. The stronger the severity of resilience, the greater the satisfaction with life and mental well-being of the juveniles surveyed. In addition, two coping strategies (seeking support from others and coping through emotions) mediated the relationship between resilience and mental well-being. Conclusions The results obtained indicate that work at the level of juvenile resilience leads to the strengthening of positive mental health indicators and buffering of negative indicators.


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