scholarly journals A simple inductive measure analysis for cardinals under the Axiom of Determinacy

Author(s):  
Stefan Bold ◽  
Benedikt Löwe
Author(s):  
Zi Di Lim ◽  
Edwin Pheng ◽  
Evelyn Tai Li Min ◽  
Hans Van Rostenberghe ◽  
Ismail Shatriah

Platelets are a primary source of pro- and anti-angiogenic cytokines. However, the evidence of their role in retinopathy of prematurity (ROP) is controversial. This retrospective study aimed to compare mean weekly platelet counts between infants with and without ROP over the first 6 weeks of life. A total of 93 infants matched by gestational age and birth weight were recruited (31 with ROP, 62 without ROP). Weekly mean platelet counts and other related risk factors were documented. The repeated measure analysis of variance (ANOVA) and the repeated measure analysis of covariance (ANCOVA) were used to compare mean platelet counts over time between the two groups, with and without adjusting for confounders. We found significant differences in the weekly mean platelet counts of infants with and without ROP over the first 6 weeks of life (p = 0.002). These differences disappeared after adjusting for covariates (p = 0.489). Lower mean platelet counts in ROP infants are not directly related to ROP, but rather to the presence of other risk factors for ROP, such as culture-proven sepsis, blood transfusion and bronchopulmonary dysplasia.


2021 ◽  
Vol 194 ◽  
pp. 107058
Author(s):  
Yun Geng ◽  
Jinlong Dong ◽  
Xinggui Chen ◽  
Luyang Zhang ◽  
Jing Yan ◽  
...  

Author(s):  
Samer Mheissen ◽  
Haris Khan ◽  
Mohammed Almuzian ◽  
Emad Eddin Alzoubi ◽  
Nikolaos Pandis

Summary Background In orthodontic trials, longitudinal designs with multiple outcome measurements over time are common. The aim of this epidemiological study was to examine whether optimal statistical analysis approaches have been used in longitudinal orthodontic trials. Methods Pubmed was searched in August 2021 for longitudinal orthodontic trials with at least three time points of outcome assessment published in the 2017–20 period. Study selection and data extraction were done independently and in duplicate. The analysis approaches undertaken were tabulated and associations between study characteristics and the use of optimal analysis or not were assessed using Fisher’s exact test and logistic regression. Results One hundred forty-seven out of 563 unique records were deemed eligible for inclusion. Only 26.50% of these trials used an optimal statistical analysis for longitudinal data where the data structure is accounted for. None of the study characteristics except the statistical significance of the results were associated with the appropriateness of the statistical analysis. The odds of significant results in studies with suboptimal analyses were higher than that in studies with optimal longitudinal analyses (odds ratio: 3.48, 95% confidence interval: 1.62, 7.46, P = 0.001). For the studies with optimal analysis, the most frequent test was repeated-measure analysis of variance (RM-ANOVA). The reporting of the statistical analysis section was suboptimal in the majority of the trials. Conclusion Most longitudinal orthodontic trials are not analysed using optimal statistical approaches. Inferences and interpretation of their results are likely to be compromised.


2015 ◽  
Vol 8 (1) ◽  
pp. 35
Author(s):  
Willian Travain ◽  
Hanna Carolina Bet Dos Santos ◽  
Valéria Schoffen Romao Carrascoza ◽  
Márcia Do Nascimento Brito ◽  
Célia Regina Godoy Gomes

O objetivo desse estudo foi avaliar a influência do óleo de coco sobre morfologia da aorta torácica. Foram utilizados 23 animais, com 120 dias de idade. Os animais foram inicialmente separados em dois grupos, controle (tratado com dieta padrão para roedores) e obeso (tratado com dieta hipercalórica para induzir a obesidade). Aos 90 dias, os animais dos grupos controle e obeso foram subdivididos em dois grupos adicionais: C/ag, C/co, O/ag, O/co. Aos 120 dias foram eutanasiados com pentobarbitol sódico. As aortas torácicas extraídas foram processadas histologicamente e coradas com Tricrômico de Masson e Orceína-picrussírus-hematoxilina para visualização dos componentes colágeno, músculo liso e elástico, seguida da quantificação realizada por densidade de volume. Realizou-se a medida íntima-média, para verificação da espessura do vaso. A estatística seguiu Análise de Variância de um fator (ANOVA), seguida pelo teste de Tukey, para nível de significância de 5%. Concluímos que a utilização de óleo de coco em ratos obesos parece induzir uma remodelação vascular marcada pela diminuição na composição de colágeno e aumento de células musculares lisas em ratos obesos tratados com óleo de coco. Effects of Coconut Oil on the Morphology of Obese Rats´ Aorta ABSTRACT: Current study analyzes the influence of coconut oil on the morphology of the thorax aorta in 23 rats aged 120 days. The animals were separated into two groups, control (treated with standard ration for rodents) and obese (treated with a hypercaloric diet to induce obesity). After 90 days the control and obese groups were subdivided into two additional groups: C/ag, C/co, O/ag, O/co. On the 120th day the rats were euthanized with sodium pentobarbitol. The thorax aortas were removed and histologically processed. They were stained with Masson Trichromium and orcein-picrosirius-hematoxylin to visualize collagen components, smooth and elastic muscle, followed by volume density. Vessel thickness was evaluated by intima-media measure. Analysis of variance (ANOVA) and Tukey´s test were employed at 5% significance. The use of coconut oil in obese rats may have induced vascular re-modeling by decreasing the composition of collagen and increasing the smooth muscle cells in obese rats treated with coconut oil.


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