scholarly journals The Relationship Between Caffeine Intake and Immunological and Virological Markers of HIV Disease Progression in Miami Adult Studies on HIV Cohort

2017 ◽  
Vol 30 (4) ◽  
pp. 271-277 ◽  
Author(s):  
Venkataraghavan Ramamoorthy ◽  
Adriana Campa ◽  
Muni Rubens ◽  
Sabrina S. Martinez ◽  
Christina Fleetwood ◽  
...  
2011 ◽  
Vol 41 (1) ◽  
pp. 14-20 ◽  
Author(s):  
Han-Zhu Qian ◽  
Samuel E. Stinnette ◽  
Peter F. Rebeiro ◽  
Aaron M. Kipp ◽  
Bryan E. Shepherd ◽  
...  

2003 ◽  
Vol 131 (3) ◽  
pp. 1117-1123 ◽  
Author(s):  
F. TYRER ◽  
A. S. WALKER ◽  
J. GILLETT ◽  
K. PORTER

Seroconversion illness is known to be associated with more rapid HIV disease progression. However, symptoms are often subjective and prone to recall bias. We describe symptoms reported as seroconversion illness and examine the relationship between illness, HIV test interval (time between antibody-negative and anibody-positive test dates) and the effect of both on time to AIDS from seroconversion. We used a Cox model, adjusting for age, sex, exposure group and year of estimated seroconversion. Of 1820 individuals, information on seroconversion illness was available for 1244 of whom 423 (34%) reported symptomatic seroconversion. Persons with a short test interval ([les ]2 months) were significantly more likely to report an illness than people with a longer interval (OR 6·76, 95% CI 4·75–9·62). Time to AIDS was significantly faster (P=0·01) in those with a short test interval. The HIV test interval is a useful replacement for information on seroconversion illness in studies of HIV disease progression.


1993 ◽  
Vol 4 (1) ◽  
pp. 49-51 ◽  
Author(s):  
G A Garden ◽  
G B Moss ◽  
W Emonyi ◽  
J Bwayo ◽  
P Velentgas ◽  
...  

Serum beta-2 microglobulin (β2-M) has prognostic value similar to lymphocyte profiles for predicting disease progression in those infected with the human immunodeficiency virus (HIV). However, the relationship between β2-M and HIV disease progression among inhabitants of countries with endemic tropical diseases has not been evaluated. To determine the relationship between serum β2-M levels and HIV infection and disease status in an African population, serum β2-M levels were measured in 369 patients attending a sexually transmitted disease (STD) clinic in Nairobi, Kenya. Mean serum β2-M was significantly higher in HIV seropositive than in HIV seronegative individuals. Among HIV infected patients, higher mean β2-M levels were observed in those with HIV associated symptoms or laboratory markers of advanced HIV disease. Significant inverse correlations between β2-M and the percentage of CD4 lymphocytes or CD4/CD8 ratio were found. These findings suggest that β2-M measurements may have prognostic value for HIV infected populations in developing countries.


Nutrients ◽  
2021 ◽  
Vol 13 (3) ◽  
pp. 868
Author(s):  
Jorge Lorenzo Calvo ◽  
Xueyin Fei ◽  
Raúl Domínguez ◽  
Helios Pareja-Galeano

Cognitive functions are essential in any form of exercise. Recently, interest has mounted in addressing the relationship between caffeine intake and cognitive performance during sports practice. This review examines this relationship through a structured search of the databases Medline/PubMed and Web of Science for relevant articles published in English from August 1999 to March 2020. The study followed PRISMA guidelines. Inclusion criteria were defined according to the PICOS model. The identified records reported on randomized cross-over studies in which caffeine intake (as drinks, capsules, energy bars, or gum) was compared to an identical placebo situation. There were no filters on participants’ training level, gender, or age. For the systematic review, 13 studies examining the impacts of caffeine on objective measures of cognitive performance or self-reported cognitive performance were selected. Five of these studies were also subjected to meta-analysis. After pooling data in the meta-analysis, the significant impacts of caffeine only emerged on attention, accuracy, and speed. The results of the 13 studies, nevertheless, suggest that the intake of a low/moderate dose of caffeine before and/or during exercise can improve self-reported energy, mood, and cognitive functions, such as attention; it may also improve simple reaction time, choice reaction time, memory, or fatigue, however, this may depend on the research protocols.


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