The characteristics of iodine nutrition status in China after 20 years of USI: an epidemiology study covering 31 provinces

Thyroid ◽  
2021 ◽  
Author(s):  
Liu Tingting ◽  
Yongze Li ◽  
Di Teng ◽  
Xiaoguang Shi ◽  
Li Yan ◽  
...  
Keyword(s):  
Nutrition Status ◽  
Epidemiology Study ◽  
Iodine Nutrition

Impact of iodine nutrition status on thyroid autoimmunity in subclinical hypothyroid patients attending a tertiary hospital of Bangladesh

2018 ◽  
Vol 15 (2) ◽  
pp. 75
Author(s):  
Md Asaduzzaman ◽  
AB M Kamrul-Hasan ◽  
AK M Aminul-Islam ◽  
Md Rafiq-Uddin ◽  
MA Hasanat ◽  
...  
Keyword(s):  
Thyroid Autoimmunity ◽  
Tertiary Hospital ◽  
Nutrition Status ◽  
Iodine Nutrition ◽  
Hypothyroid Patients

scholarly journals Association between Iodine Nutrition Status and Thyroid Disease-Related Hormone in Korean Adults: Korean National Health and Nutrition Examination Survey VI (2013–2015)

Nutrients ◽  
2019 ◽  
Vol 11 (11) ◽  
pp. 2757 ◽  
Author(s):  
Kim ◽  
Kwon ◽  
Kim ◽  
Hong ◽  
Park
Keyword(s):  
National Health ◽  
Thyroid Disease ◽  
Urinary Iodine ◽  
Iodine Intake ◽  
Thyroid Stimulating Hormone ◽  
Nutrition Status ◽  
Urinary Iodine Concentration ◽  
Nutrition Examination Survey ◽  
Iodine Nutrition ◽  
Health And Nutrition

This study aimed to observe the relationship between iodine nutrition status (dietary iodine intake and estimated iodine intake based on urinary iodine concentration (UIC)) and thyroid disease-related hormones. This study involved 6090 subjects >19 years old with valid UIC, assessed between 2013 and 2015 by the Korean National Health and Nutrition Examination Survey, using a stratified, multistage, clustered probability-sampling design. The estimated iodine intake in participants was measured using UIC and urine creatinine. To examine the effect of iodine intake on thyroid disease, the iodine intake was divided into Korean Dietary Reference Intakes groups, and logistic regression analysis was performed via the surveylogistic procedure to obtain odds ratios (ORs) and 95% confidence intervals (CIs). The estimated iodine intake showed a significant positive correlation with dietary iodine intake (r = 0.021, p < 0.001), UIC (r = 0.918, p < 0.001), and thyroid-stimulating hormone (TSH) (r = 0.043, p < 0.001), but a significant negative correlation with free thyroxine (FT4) (r = −0.037, p < 0.001). Additionally, as the estimated iodine intake increased, age, TSH, and UIC increased, but FT4 decreased (p for trend < 0.0001). The risk of thyroid disease was higher in the “≥tolerable upper intake level (UL ≥ 2400 µg/day)” group than in the “<estimated average requirement (EAR < 150 µg/day)” group in females (OR: 2.418; 95% CI: 1.010–5.787). Also, as iodine intake increased, the risk of thyroid disease increased (p for trend < 0.038).

Iodine Nutrition Status in Pregnant Women in Mexico

Thyroid ◽  
2011 ◽  
Vol 21 (12) ◽  
pp. 1367-1371 ◽  
Author(s):  
Pablo García-Solís ◽  
Juan Carlos Solís-S ◽  
Ana Cristina García-Gaytán ◽  
Vanessa Amaranta Reyes-Mendoza ◽  
Ludivina Robles-Osorio ◽  
...  
Keyword(s):  
Pregnant Women ◽  
Nutrition Status ◽  
Iodine Nutrition

Iodine nutrition status of women after 10 years of Lipiodol supplementation: a cross-sectional study in Xinjiang, China

2020 ◽  
pp. 1-13
Author(s):  
Lixiang Liu ◽  
Peng Liu ◽  
Qin Lin ◽  
Xiaohui Su ◽  
Jia Huang ◽  
...  
Keyword(s):  
Iodine Deficiency ◽  
Urinary Iodine ◽  
Thyroid Volume ◽  
Nutrition Status ◽  
Thyroid Peroxidase ◽  
Urinary Iodine Concentration ◽  
Free Triiodothyronine ◽  
Iodine Nutrition ◽  
Detection Rates ◽  
Status Of Women

Abstract This study examined the contribution of long-term use of Lipiodol capsules, as a supplement to iodised salt to the control of iodine deficiency disorders among women in Xinjiang of China. A total of 1220 women across Kashgar, Aksu, Turpan and Yili Prefectures were surveyed in 2017. Lipiodol capsules were administered twice yearly in Kashgar and once yearly in Aksu and Turpan, but not in Yili. Urinary iodine concentration (UIC), free triiodothyronine (FT3), free thyroxine (FT4), thyroid-stimulating hormone (TSH), thyroglobulin antibody, thyroid peroxidase antibody and thyroid volume values were assessed. All the women in the four areas were in a state of non-iodine deficiency by UIC. The UIC were higher than adequate in Kashgar and Aksu (619·4 v. 278·6 μg/l). Thyroid hormone levels differed significantly in Turpan and Yili (FT3: 4·4 v. 4·6 pmol/l, FT4: 13·8 v. 14·2 pmol/l, TSH: 2·0 v. 2·7 mIU/l), but did not differ significantly in Kashgar, Aksu and Yili. The four areas did not differ significantly with regard to thyroid nodules, autoimmune thyroiditis or goitre. However, the detection rates of subclinical hypothyroidism (16·6 %) and total thyroid dysfunction (25·4 %) were higher among women in Yili. The supplementation with Lipiodol capsules had improved the iodine nutrition status of women in iodine-deficient areas of Xinjiang since 2006. To avoid negative effects of excess iodine, we suggest a gradual discontinuation of Lipiodol capsules in women with special needs based on the existing iodine nutrition level of local women.

scholarly journals Changes in the Demographic and Clinicopathological Characteristics of Thyroid Cancer: A Population-Based Investigation in Algeria, 1993-2013

2020 ◽  
Vol 2020 ◽  
pp. 1-11
Author(s):  
Houda Boukheris ◽  
Arslan Bettayeb ◽  
Lesley Ann Anderson ◽  
Zineb Achour ◽  
Fatma Zohra Benbachir ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Case Series ◽  
Population Based ◽  
Clinicopathological Characteristics ◽  
Nutrition Status ◽  
Iodine Nutrition ◽  
Molecular Features ◽  
International Trends ◽  
Histologic Types ◽  
Over Time

Over the last three decades, the incidence of thyroid cancer has increased worldwide. The reasons for this increase remain controversial. In Algeria, however, to date, information on thyroid cancer has been limited to a hospital-based case series. We analyzed data from a population-based cohort study in Oran District, Algeria, to describe demographic and clinicopathological characteristics of patients diagnosed with thyroid cancer between 1993 and 2013. Medical records and pathology reports of thyroid cancer patients who had surgery were reviewed. Changes in demographic and clinicopathological features over the 21-year period are described. During the study period, thyroid cancer was diagnosed in 1248 women (86.5%, mean age 43.7±15.2 years) and 195 men (23.4%, mean age 48.1±15.9 years). Most cases (83.1% for women and 69.8% for men) sought a diagnosis following a self-neck check. The most common histologic types were papillary (58.3%), follicular (29.7%), anaplastic (4.1%), and medullary (0.8%) carcinomas. The incidence of papillary carcinomas significantly increased (p<0.001) while the incidence of other histologic types significantly decreased over time. Tumor size overall significantly decreased (p<0.001) while the frequency of small (≤20 mm) and larger (>20 mm) carcinomas significantly increased (p<0.05). The frequency of thyroid cancers with capsular effractions and angioinvasions also decreased over time. Thyroid cancer incidence in Algeria has increased substantially in line with international trends with changes in clinical practice being a possible contributing factor. However, the increasing papillary-to-follicular cancer ratio may be due to changes in iodine nutrition status in Algeria. Further research, including exploration of biological and molecular features of thyroid cancer, will enable a better understanding of risk factors and etiopathogenetic mechanisms.

scholarly journals Can postpartum maternal urinary iodine be used to estimate iodine nutrition status of newborns?

2016 ◽  
Vol 115 (7) ◽  
pp. 1226-1231 ◽  
Author(s):  
Pantea Nazeri ◽  
Parvin Mirmiran ◽  
Mehdi Hedayati ◽  
Yadollah Mehrabi ◽  
Hossein Delshad ◽  
...  
Keyword(s):  
Urinary Iodine ◽  
Cross Sectional Study ◽  
Thyroid Stimulating Hormone ◽  
Nutrition Status ◽  
Iodine Nutrition ◽  
Cross Sectional ◽  
Young Infants ◽  
Significant Difference ◽  
Heel Prick ◽  
Postpartum Mothers

AbstractI deficiency can lead to detrimental effects, particularly in neonates and young infants. The aim of this study was to explore whether postpartum maternal urinary I can be used to estimate the I status of newborns. In this cross-sectional study conducted in Tehran, lactating mothers and newborns, within 3–5 d postpartum, were randomly selected. Urine samples were collected from each mother and newborn, and a heel-prick blood sample was obtained from all newborns as part of the routine national newborn screening programme. According to the WHO criteria, median urinary I concentration (UIC) <100 µg/l and frequency over 3 % of thyroid stimulating hormone (TSH) >5 mIU/l was considered as I insufficiency. A total of 147 postpartum women and neonates, aged 27·8 (sd5·3) years and 4·2 (sd0·6) d, respectively, completed this study. The median UIC was 68·0 (interquartile range (IQR) 39·4–133·5) and 212·5 (IQR 92·3–307·3) µg/l in postpartum mothers and newborns, respectively. The median neonatal TSH was 1·00 (IQR 0·50–1·70) mIU/l. There was no significant difference in the neonatal UIC and TSH of infants whose mothers had deficient and sufficient urinary I. In the multiple linear regression, neonatal UIC value was associated with maternal urinary I (P=0·048) and parity (P=0·039); a significant association was observed between neonatal TSH and infant sex (P=0·038) and birth weight (P=0·049). The findings of our study demonstrate that, despite postpartum mothers being mildly I deficient, I status of their infants was adequate as assessed by UIC and TSH values. It seems factors other than maternal urinary I may influence the I status in newborns.

scholarly journals Iodine Nutrition Status of Pregnant Women in an Iodine-Sufficient Area

2009 ◽  
Vol 30 (4) ◽  
pp. 351-354 ◽  
Author(s):  
Husref Tahirović ◽  
Alma Toromanović ◽  
Adem Balić ◽  
Sanja Grbić ◽  
Daniella Gnat
Keyword(s):  
Pregnant Women ◽  
Nutrition Status ◽  
Iodine Nutrition

scholarly journals Thyroid dysfunction in region of excess iodine intake of Eastern Nepal

2018 ◽  
Vol 4 (5) ◽  
pp. 114
Author(s):  
Saroj Thapa ◽  
Madhab Lamsal ◽  
Rajendra K. Chaudhari ◽  
Basanta Gelal ◽  
Saroj Kunwar ◽  
...  
Keyword(s):  
Primary School ◽  
Subclinical Hypothyroidism ◽  
Thyroid Dysfunction ◽  
Urinary Iodine ◽  
Iodine Concentration ◽  
Primary School Children ◽  
Nutrition Status ◽  
Urinary Iodine Concentration ◽  
Iodine Nutrition ◽  
Excess Iodine

<p class="abstract"><strong>Background:</strong> Iodine deficiency as well as iodine excess can result in an increased prevalence of thyroid disorders. The prevalence of excess iodine nutrition is increasing all over the world. The aim of the present study was to find the occurrence of iodine nutrition status in primary school children of Eastern Nepal and find the prevalence of associated thyroid dysfunction among those with excess urinary iodine concentration.</p><p class="abstract"><strong>Methods:</strong> A community based cross sectional study was conducted in Udayapur district which is located in Eastern part of Nepal. Primary school aged children (6 years to 12 years) were enrolled in this study from three schools. Blood and urine samples were collected and assayed for urinary iodine concentration (UIC), free thyroid hormones (fT<sub>3</sub> and fT<sub>4</sub>), and thyroid stimulating hormone (TSH).  </p><p class="abstract"><strong>Results:</strong> The median UIC was 232.27 µg/L. The iodine status showed that 15.5% (n=31) had low UIC, 21% (n=42) had above requirement and 36% (n=72) had excessive iodine nutrition status. The mean concentration of fT<sub>3</sub> and fT<sub>4</sub> was 2.87 pg/ml and 1.21 ng/dl respectively, while the median TSH concentration was 3.03 mIU/L. The prevalence of thyroid dysfunction was 10% (n=20) with subclinical hypothyroidism being the most common. Majority of participants with subclinical hypothyroidism had excess UIC.</p><p class="abstract"><strong>Conclusions:</strong> Above requirement and excess iodine nutrition is more common in region where there is unregulated consumption and improper monitoring of iodized salt. Subclinical hypothyroidism is common in regions of excess iodine nutrition.</p>

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