Tumor Volume Doubling Time in Active Surveillance of Papillary Thyroid Microcarcinoma: A Multicenter Cohort Study in Korea

Thyroid ◽  
2021 ◽  
Author(s):  
Meihua Jin ◽  
Hye In Kim ◽  
Jeonghoon Ha ◽  
Min Ji Jeon ◽  
Won Gu Kim ◽  
...  
Keyword(s):  
Cohort Study ◽  
Active Surveillance ◽  
Doubling Time ◽  
Tumor Volume ◽  
Papillary Thyroid ◽  
Multicenter Cohort Study ◽  
Volume Doubling Time ◽  
Thyroid Microcarcinoma ◽  
Multicenter Cohort ◽  
Volume Doubling

Tumor Volume Doubling Time in Active Surveillance of Papillary Thyroid Carcinoma

Thyroid ◽  
2019 ◽  
Vol 29 (5) ◽  
pp. 642-649 ◽  
Author(s):  
Hye-Seon Oh ◽  
Hyemi Kwon ◽  
Eyun Song ◽  
Min Ji Jeon ◽  
Tae Yong Kim ◽  
...  
Keyword(s):  
Papillary Thyroid Carcinoma ◽  
Thyroid Carcinoma ◽  
Active Surveillance ◽  
Doubling Time ◽  
Tumor Volume ◽  
Papillary Thyroid ◽  
Tumor Volume Doubling Time ◽  
Volume Doubling Time ◽  
Volume Doubling

scholarly journals Spontaneous Slowing and Regressing of Tumor Growth in Childhood/Adolescent Papillary Thyroid Carcinomas Suggested by the Postoperative Thyroglobulin-Doubling Time

2018 ◽  
Vol 2018 ◽  
pp. 1-6 ◽  
Author(s):  
Toshihiko Kasahara ◽  
Akira Miyauchi ◽  
Takumi Kudo ◽  
Eijun Nishihara ◽  
Mitsuru Ito ◽  
...  
Keyword(s):  
Tumor Growth ◽  
Doubling Time ◽  
Tumor Volume ◽  
Young Patients ◽  
Papillary Thyroid ◽  
Thyroid Carcinomas ◽  
Volume Doubling Time ◽  
Age At Surgery ◽  
Volume Doubling ◽  
Single Cancer

Background. Children and adolescents with papillary thyroid carcinomas (PTCs) have generally excellent prognoses despite their frequent extended disease. The tumor growth of young patients’ PTCs might show spontaneous slowing postoperatively. We compared young PTC patients’ postoperative thyroglobulin-doubling time (Tg-DT) with their preoperative hypothetical tumor volume-doubling time (hTV-DT). Methods. Fourteen PTC patients aged ≤18 years who underwent total thyroidectomy at Kuma Hospital in 1998–2016 had biochemically persistent disease postoperatively. We calculated their Tg-DTs and estimated their preoperative TV-DTs with the tumor size and the patient’s age at surgery, presuming that a single cancer cell was present at the patient’s birth. Results. Twelve patients had positive Tg-DTs ranging from 2.0 to 147 years, and the remaining two had negative Tg-DTs, indicating slow growth or even regression. The hTV-DTs were 0.3–0.6 years (median 0.5 years), which were significantly shorter than the Tg-DTs (p<0.001), indicating much faster growth preoperatively. The analyses of the nine patients without radioactive iodine administration (RAI) gave similar results (p<0.01). Conclusions. Irrespective of RAI, the patients’ postoperative Tg-DTs were significantly longer than their preoperative hTV-DTs and were negative values in two patients, indicating that the growth of these young patients’ PTCs had spontaneously slowed or even regressed postoperatively.

Determining Whether Tumor Volume Doubling Time and Growth Rate Can Predict Malignancy After Delayed Diagnostic Surgery of Follicular Neoplasm

Thyroid ◽  
2019 ◽  
Vol 29 (10) ◽  
pp. 1418-1424 ◽  
Author(s):  
Mijin Kim ◽  
Sae Rom Chung ◽  
Min Ji Jeon ◽  
Minkyu Han ◽  
Jeong Hyun Lee ◽  
...  
Keyword(s):  
Growth Rate ◽  
Doubling Time ◽  
Tumor Volume ◽  
Follicular Neoplasm ◽  
Tumor Volume Doubling Time ◽  
Volume Doubling Time ◽  
Volume Doubling
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