Pro64His (rs4644) polymorphism within galectin-3 is a risk factor of differentiated thyroid carcinoma and affects the transcriptome of thyrocytes engineered via CRISPR/Cas9 system.

Thyroid ◽  
2020 ◽  
Author(s):  
Alda Corrado ◽  
Romina Aceto ◽  
Roberto Silvestri ◽  
Irene Dell'Anno ◽  
Benedetta Ricci ◽  
...  
Keyword(s):  
Risk Factor ◽  
Thyroid Carcinoma ◽  
Differentiated Thyroid Carcinoma ◽  
Galectin 3

scholarly journals Positive family history of thyroid disease as a risk factor for differentiated thyroid carcinoma

2011 ◽  
Vol 121 (12) ◽  
pp. 441-447 ◽  
Author(s):  
Elwira Przybylik-Mazurek ◽  
Dorota Pach ◽  
Sylwia Kuźniarz-Rymarz ◽  
Marta Tracz-Bujnowicz ◽  
Krystyna Szafraniec ◽  
...  
Keyword(s):  
Risk Factor ◽  
Family History ◽  
Thyroid Carcinoma ◽  
Thyroid Disease ◽  
Positive Family History ◽  
Differentiated Thyroid Carcinoma ◽  
History Of

scholarly journals Evidences that the polymorphism Pro-282-Ala within the tumor suppressor gene WWOX is a new risk factor for differentiated thyroid carcinoma

2011 ◽  
Vol 129 (12) ◽  
pp. 2816-2824 ◽  
Author(s):  
Lisa Cancemi ◽  
Cristina Romei ◽  
Sara Bertocchi ◽  
Giulia Tarrini ◽  
Irene Spitaleri ◽  
...  
Keyword(s):  
Risk Factor ◽  
Tumor Suppressor ◽  
Thyroid Carcinoma ◽  
Tumor Suppressor Gene ◽  
Suppressor Gene ◽  
Differentiated Thyroid Carcinoma

scholarly journals RESULTS OF RESEARCH OF GALECTIN-3 AND THYROGLOBULIN IN PATIENTS WITH THYROID NODULES

2015 ◽  
Vol 174 (2) ◽  
pp. 81-83
Author(s):  
O. S. Olifirova ◽  
S. V. Knalyan
Keyword(s):  
Thyroid Gland ◽  
Thyroid Carcinoma ◽  
Fine Needle Aspiration ◽  
Thyroid Nodules ◽  
Fine Needle Aspiration Biopsy ◽  
Needle Aspiration ◽  
Differentiated Thyroid Carcinoma ◽  
Fine Needle ◽  
Galectin 3 ◽  
Benign Nodules

An investigation of galectin-3 and thyroglobulin using IFA was conducted in 80 patients. A lavage of aspirate from the thyroid gland was obtained by fine-needle aspiration biopsy. It was stated that significant increase of galectin-3 and thyroglobulin was noted in case of high differentiated thyroid carcinoma in comparison with benign nodules. Galectin-3 and thyroglobulin from the lavage of thyroid gland aspirate could be used as an oncological marker for complex differentiated diagnostics of high differentiated thyroid carcinoma and benign nodules.

scholarly journals Pre-operative serum TSH levels: A risk factor for advanced metastatic differentiated thyroid carcinoma

2019 ◽  
Vol 35 (5) ◽  
Author(s):  
Sumera Batool ◽  
Muhammad Shakir Afridi ◽  
Adeel Akbar Khoja ◽  
Najmul Islam
Keyword(s):  
Risk Factor ◽  
Thyroid Cancer ◽  
Lymph Node ◽  
Thyroid Carcinoma ◽  
Distant Metastasis ◽  
Differentiated Thyroid Carcinoma ◽  
Thyroid Cancers ◽  
Multifocal Disease ◽  
Serum Tsh ◽  
Tsh Levels

Background and Objective: As the thyroid cancer incidence is increasing, the search for its risk factor is becoming more important. Serum thyroid stimulating hormone (TSH) levels being a growth factor for normal thyroid tissue, is also considered as growth promotor of cancer cells. In our study we aimed for pre-operative serum TSH levels of Differentiated thyroid cancers (DTC) done before their first surgery and determined its association with advanced disease in terms of stage, multifocal disease, lymph node involvement and distant metastasis. Methods: We have conducted a retrospective review of thyroid cancers from 1st January 2008 to 31st December 2017. Out of 281, 142 cases were included according to inclusion criteria. We noted the demographic details of participants, their histopathological diagnosis and serum TSH levels done before first surgery from the medical records. We calculated the stage of tumor through modified American Joint Committee (AJCC) staging system. Results: Out of 147 participants, 89.4% had papillary carcinoma or its variants whereas 10.6% reported follicular carcinoma. The mean pre-op TSH level of the patients included was 2.04 ± 1.79. In addition to the descriptive analysis, the univariate regression analysis revealed that the association of serum TSH levels was found to be statistically insignificant with advanced stage of thyroid cancer, multifocal disease, lymph node metastasis and distant metastasis respectively. Conclusion: The serum TSH levels before surgery was not associated with poor prognosis of differentiated thyroid cancer with respect to higher staging, multifocal disease, lymphatic or distant metastasis. doi: https://doi.org/10.12669/pjms.35.5.704 How to cite this:Batool S, Afridi MS, Khoja A, Islam N. Pre-operative serum TSH levels: A risk factor for advanced metastatic differentiated thyroid carcinoma. Pak J Med Sci. 2019;35(5):---------. doi: https://doi.org/10.12669/pjms.35.5.704 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Thyroid peroxidase and galectin-3 immunostaining in differentiated thyroid carcinoma with clinicopathologic correlation

2008 ◽  
Vol 39 (11) ◽  
pp. 1656-1663 ◽  
Author(s):  
Svetlana Savin ◽  
Dubravka Cvejic ◽  
Tijana Isic ◽  
Ivan Paunovic ◽  
Svetislav Tatic ◽  
...  
Keyword(s):  
Thyroid Carcinoma ◽  
Differentiated Thyroid Carcinoma ◽  
Thyroid Peroxidase ◽  
Clinicopathologic Correlation ◽  
Galectin 3
Sign in / Sign up

Export Citation Format

Share Document