Comprehensive DNA Methylation Profiling Identifies Novel Diagnostic Biomarkers for Thyroid Cancer

Thyroid ◽  
2020 ◽  
Vol 30 (2) ◽  
pp. 192-203
Author(s):  
Jong-Lyul Park ◽  
Sora Jeon ◽  
Eun-Hye Seo ◽  
Dong Hyuck Bae ◽  
Young Mun Jeong ◽  
...  
Keyword(s):  
Dna Methylation ◽  
Thyroid Cancer ◽  
Diagnostic Biomarkers ◽  
Dna Methylation Profiling ◽  
Methylation Profiling

scholarly journals DNA methylation profiling reveals novel diagnostic biomarkers in renal cell carcinoma

BMC Medicine ◽  
2014 ◽  
Vol 12 (1) ◽  
Author(s):  
Brittany N Lasseigne ◽  
Todd C Burwell ◽  
Mohini A Patil ◽  
Devin M Absher ◽  
James D Brooks ◽  
...  
Keyword(s):  
Dna Methylation ◽  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Diagnostic Biomarkers ◽  
Dna Methylation Profiling ◽  
Methylation Profiling

scholarly journals DNA Methylation Profiling of MYC, SMAD2/3 and DNMT3A in Colorectal Cancer

2021 ◽  
Author(s):  
Seyedeh Elham Norollahi ◽  
Maryam Gholamniya Foumani ◽  
Maryam Khoshbakht Pishkhan ◽  
Afshin Shafaghi ◽  
Majid Alipour ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Dna Methylation ◽  
Cancer Progression ◽  
Promoter Methylation ◽  
Tumor Suppressor Genes ◽  
Molecular Heterogeneity ◽  
Diagnostic Biomarkers ◽  
Rna Remodeling ◽  
Dna Methylation Profiling ◽  
Methylation Profiling

Epigenetic modifications particularly DNA methylation is a common place and remarkable factor in carcinogenesis transformation. Conspicuously, previous findings have presented a cluster of irregular promoter methylation alterationsrelated with silencing of TSG (tumor suppressor genes), little is accepted regarding their sequential DNA methylation (Hypo and Hyper) modifications during the cancer progression. In this way, fluctuations of DNA methylation of many certain genes especially MYC, SMAD2/3 and DNMT3A have an impressive central key role in many different cancers like colorectal (CRC)one. CRC is distinguished by DNA methylation, which is related with tumorigenesis and also genomic instability. Importantly, molecular heterogeneity between multiple adenomas in different patients with CRC may show diverse developmental phenotypes for these kinds of tumors. Conclusively, studying of factors which are involved in CRC carcinogenesis, especially the alterations in epigenetic elements, such as DNA methylation besides the RNA remodeling, histone modification, histone acetylation and histone phosphorylation can be influential in order to find new therapeutic and diagnostic biomarkers in this type of malignancy. In this account, we tried to discuss and address the potential significant methylated modifications of these genes and their importance during the development of CRC carcinogenesis.

DNA methylation profiling of well-differentiated thyroid cancer uncovers markers of recurrence free survival

2014 ◽  
Vol 135 (3) ◽  
pp. 598-610 ◽  
Author(s):  
Veronika Mancikova ◽  
Raquel Buj ◽  
Esmeralda Castelblanco ◽  
Lucía Inglada-Pérez ◽  
Anna Diez ◽  
...  
Keyword(s):  
Dna Methylation ◽  
Thyroid Cancer ◽  
Differentiated Thyroid Cancer ◽  
Recurrence Free Survival ◽  
Free Survival ◽  
Dna Methylation Profiling ◽  
Well Differentiated ◽  
Methylation Profiling

Forensic DNA methylation profiling from minimal traces: How low can we go?

2018 ◽  
Vol 33 ◽  
pp. 17-23 ◽  
Author(s):  
Jana Naue ◽  
Huub C.J. Hoefsloot ◽  
Ate D. Kloosterman ◽  
Pernette J. Verschure
Keyword(s):  
Dna Methylation ◽  
Forensic Dna ◽  
Dna Methylation Profiling ◽  
Methylation Profiling

scholarly journals DNA Methylation Profiling of Uniparental Disomy Subjects Provides a Map of Parental Epigenetic Bias in the Human Genome

2016 ◽  
Vol 99 (3) ◽  
pp. 555-566 ◽  
Author(s):  
Ricky S. Joshi ◽  
Paras Garg ◽  
Noah Zaitlen ◽  
Tuuli Lappalainen ◽  
Corey T. Watson ◽  
...  
Keyword(s):  
Dna Methylation ◽  
Human Genome ◽  
Uniparental Disomy ◽  
Dna Methylation Profiling ◽  
Methylation Profiling
Sign in / Sign up

Export Citation Format

Share Document