scholarly journals Clinical Applicability of Low Levels of Thyroglobulin Autoantibodies as Cutoff Point for Thyroglobulin Autoantibody Positivity

Thyroid ◽  
2019 ◽  
Vol 29 (1) ◽  
pp. 71-78 ◽  
Author(s):  
Bernadette L. Dekker ◽  
Anouk N.A. van der Horst-Schrivers ◽  
Wim J. Sluiter ◽  
Adrienne H. Brouwers ◽  
Eef G.W.M. Lentjes ◽  
...  
PEDIATRICS ◽  
1982 ◽  
Vol 69 (3) ◽  
pp. 260-266 ◽  
Author(s):  
Dorothy A. Ritter ◽  
John D. Kenny ◽  
H. James Norton ◽  
Arnold J. Rudolph

To assess the value of free bilirubin (FB) measurements in predicting kernicterus (KI) in sick premature infants, 91 newborns weighing less than 1,500 gm at birth were observed during the first week of life with twice daily FB and total bilirubin determinations. Autopsies were performed on 30 of the 53 infants who died. Seven had KI and 23 did not. There were no differences between infants with and without KI in the maximum FB level (KI 18.2 ± 4.5 [SEM] nm/liter, no KI 11.1 ± 0.9 nm/liter, P not significant) or the total bilirubin level (KI 7.3 ± 1.3 mg/100 ml, no KI 6.1 ± 0.5 mg/100 ml, P not significant). In fact, three kernicteric infants had very low maximum FB levels (<10 nm/liter). These three infants had prolonged episodes of acidosis, hypoxemia, or hypothermia during the 24 hours preceding their maximum level of FB. Although elevated levels of FB may be predictive of KI in some infants, other factors may make the blood-brain barrier more permeable to low levels of FB. This may limit the clinical applicability of FB measurements.


2005 ◽  
Vol 46 (2) ◽  
pp. 368 ◽  
Author(s):  
George Tsirpanlis ◽  
Fotini Alevyzaki ◽  
George Triantafyllis ◽  
Stylianos Chatzipanagiotou ◽  
Chrysoula Nicolaou

Thyroid ◽  
2016 ◽  
Vol 26 (6) ◽  
pp. 798-806 ◽  
Author(s):  
Francesco Latrofa ◽  
Debora Ricci ◽  
Eleonora Sisti ◽  
Paolo Piaggi ◽  
Chiara Nencetti ◽  
...  

2018 ◽  
Vol 58 (4) ◽  
pp. 19
Author(s):  
Samantha Dodt Farias ◽  
Eveline Gadelha Pereira Fontenele ◽  
Rosana Quezado ◽  
Ana Rosa Pinto Quidute ◽  
Ludmilla Aline Guimarães Moreira Farias ◽  
...  

Objective: To propose a waist-to-height ratio (WtHR) cutoff point for metabolic risk in Brazilian Turner syndrome (TS) patients. Methods: Retrospective study of anthropometric, clinical and biochemical data related to the metabolic syndrome (MS) of 45 TS patients at a specialized center. The accuracy and area under the receiver operating characteristic (ROC) curve of body mass index (BMI), waist circumference (WC) and WtHR to identify the presence of at least one of the biochemical components of MS were calculated. Results: The average age was 23.8 years (4-61 years), 43% were overweight and 11% had MS. At least one component of MS was present in 80% of the patients, being more common central obesity, low levels of HDL and dysglycemia. None had diabetes. Patients with some of the biochemical changes in MS had higher WtHR than those without metabolic alterations (0.57 vs. 0.48, P = 0.001). In adult patients (20-61 years, n = 28) the WtHR > 0.5 had 87% sensitivity and 80% specificity to identify patients with some component of MS, demonstrating greater accuracy than BMI or WC. Conclusion: We propose a WtHR cutoff point of 0.5 for metabolic risk screening in Brazilian TS patients.


2008 ◽  
Vol 41 (18) ◽  
pp. 16
Author(s):  
DIANA MAHONEY
Keyword(s):  

2017 ◽  
Vol 76 (4) ◽  
pp. 145-153 ◽  
Author(s):  
Jana Nikitin ◽  
Alexandra M. Freund

Abstract. Establishing new social relationships is important for mastering developmental transitions in young adulthood. In a 2-year longitudinal study with four measurement occasions (T1: n = 245, T2: n = 96, T3: n = 103, T4: n = 85), we investigated the role of social motives in college students’ mastery of the transition of moving out of the parental home, using loneliness as an indicator of poor adjustment to the transition. Students with strong social approach motivation reported stable and low levels of loneliness. In contrast, students with strong social avoidance motivation reported high levels of loneliness. However, this effect dissipated relatively quickly as most of the young adults adapted to the transition over a period of several weeks. The present study also provides evidence for an interaction between social approach and social avoidance motives: Social approach motives buffered the negative effect on social well-being of social avoidance motives. These results illustrate the importance of social approach and social avoidance motives and their interplay during developmental transitions.


2017 ◽  
Vol 76 (3) ◽  
pp. 107-116 ◽  
Author(s):  
Klea Faniko ◽  
Till Burckhardt ◽  
Oriane Sarrasin ◽  
Fabio Lorenzi-Cioldi ◽  
Siri Øyslebø Sørensen ◽  
...  

Abstract. Two studies carried out among Albanian public-sector employees examined the impact of different types of affirmative action policies (AAPs) on (counter)stereotypical perceptions of women in decision-making positions. Study 1 (N = 178) revealed that participants – especially women – perceived women in decision-making positions as more masculine (i.e., agentic) than feminine (i.e., communal). Study 2 (N = 239) showed that different types of AA had different effects on the attribution of gender stereotypes to AAP beneficiaries: Women benefiting from a quota policy were perceived as being more communal than agentic, while those benefiting from weak preferential treatment were perceived as being more agentic than communal. Furthermore, we examined how the belief that AAPs threaten men’s access to decision-making positions influenced the attribution of these traits to AAP beneficiaries. The results showed that men who reported high levels of perceived threat, as compared to men who reported low levels of perceived threat, attributed more communal than agentic traits to the beneficiaries of quotas. These findings suggest that AAPs may have created a backlash against its beneficiaries by emphasizing gender-stereotypical or counterstereotypical traits. Thus, the framing of AAPs, for instance, as a matter of enhancing organizational performance, in the process of policy making and implementation, may be a crucial tool to countering potential backlash.


Crisis ◽  
1999 ◽  
Vol 20 (2) ◽  
pp. 59-63 ◽  
Author(s):  
Antoon A. Leenaars ◽  
David Lester

Canada's rate of suicide varies from province to province. The classical theory of suicide, which attempts to explain the social suicide rate, stems from Durkheim, who argued that low levels of social integration and regulation are associated with high rates of suicide. The present study explored whether social factors (divorce, marriage, and birth rates) do in fact predict suicide rates over time for each province (period studied: 1950-1990). The results showed a positive association between divorce rates and suicide rates, and a negative association between birth rates and suicide rates. Marriage rates showed no consistent association, an anomaly as compared to research from other nations.


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