FOXE1 Polymorphism Interacts with Dietary Iodine Intake in Differentiated Thyroid Cancer Risk in the Cuban Population

Thyroid ◽  
2016 ◽  
Vol 26 (12) ◽  
pp. 1752-1760 ◽  
Author(s):  
Yan Ren ◽  
Juan J. Lence-Anta ◽  
Celia M. Pereda ◽  
Mae Chappe ◽  
Milagros Velasco ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Cancer Risk ◽  
Differentiated Thyroid Cancer ◽  
Iodine Intake ◽  
Thyroid Cancer Risk ◽  
Cuban Population

scholarly journals 1107Dietary polyphenol intake and differentiated thyroid cancer risk: a population-based case-control study in New Caledonia

2021 ◽  
Vol 50 (Supplement_1) ◽  
Author(s):  
Melanie Paquet ◽  
Dominique Baron-Dubourdieu ◽  
Pascal Guénel ◽  
Thérèse Truong
Keyword(s):  
Thyroid Cancer ◽  
Cancer Risk ◽  
Differentiated Thyroid Cancer ◽  
Case Control Study ◽  
New Caledonia ◽  
Population Based ◽  
Case Control ◽  
Thyroid Cancer Risk ◽  
Polyphenol Intake ◽  
Control Study

Abstract Background Aetiology of differentiated thyroid cancer is poorly understood. Among the risk factors strongly suspected to be involved in thyroid carcinogenesis are dietary factors. Recent evidence suggests polyphenols (i.e., natural bioactive compounds found in plant species), and their anticancer properties, may deserve closer epidemiological attention. Therefore, we examined the association between polyphenol intake levels and thyroid cancer risk in New Caledonia – a Pacific archipelago with some of the highest recorded thyroid cancer incidence rates in the world. Methods Food frequency questionnaire information from a population-based case-control study was used. Daily lignan and flavonoid intakes, expressed as aglycone equivalents, were estimated using Phenol-Explorer and relevant USDA databases. Unconditional logistic regression analyses were performed on data from 324 histologically confirmed cases of papillary or follicular carcinoma, diagnosed from 1993 to 1999, and 402 controls. Polyphenol intakes were analysed as both continuous and categorical variables (quartiles). Results Estimated median flavonoid and lignan intakes were 351.0 and 2.6 mg, respectively. When adjusting for sex, age, ethnic community, province of residence, BMI, smoking status, alcohol consumption and energy intake, no association with differentiated thyroid cancer risk was observed for flavonoids (OR = 1.06, 95% CI: 0.66, 1.70; comparing extreme quartiles), but a negative association was demonstrated for lignans (ORQ4vs.Q1=0.60, 95% CI: 0.37, 0.96; comparing extreme quartiles). Conclusions Our findings suggest that lignans may exert a protective effect on differentiated thyroid cancer. However, large-scale cohort studies and further analytical data on lignans are required to confirm this association. Key messages Lignans may play a role in thyroid carcinogenesis.

scholarly journals Novel Genome-Wide Association Study–Based Candidate Loci for Differentiated Thyroid Cancer Risk

2014 ◽  
Vol 99 (10) ◽  
pp. E2084-E2092 ◽  
Author(s):  
Gisella Figlioli ◽  
Aleksandra Köhler ◽  
Bowang Chen ◽  
Rossella Elisei ◽  
Cristina Romei ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Cancer Risk ◽  
Association Study ◽  
Differentiated Thyroid Cancer ◽  
Genome Wide Association Study ◽  
Genome Wide Association ◽  
Genome Wide ◽  
Thyroid Cancer Risk ◽  
Candidate Loci

Common Variants of the Thyroglobulin Gene Are Associated with Differentiated Thyroid Cancer Risk

Thyroid ◽  
2011 ◽  
Vol 21 (5) ◽  
pp. 519-525 ◽  
Author(s):  
Abdelmounaim Akdi ◽  
Gisselle Pérez ◽  
Susana Pastor ◽  
Juan Castell ◽  
Josefina Biarnés ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Cancer Risk ◽  
Differentiated Thyroid Cancer ◽  
Common Variants ◽  
Thyroid Cancer Risk ◽  
Thyroglobulin Gene

scholarly journals Recreational Physical Activity and Differentiated Thyroid Cancer Risk: A Pooled Analysis of Two Case-Control Studies

2016 ◽  
Vol 5 (2) ◽  
pp. 132-138 ◽  
Author(s):  
Constance Xhaard ◽  
Juan J. Lence-Anta ◽  
Yan Ren ◽  
Françoise Borson-Chazot ◽  
Geneviève Sassolas ◽  
...  
Keyword(s):  
Physical Activity ◽  
Thyroid Cancer ◽  
Cancer Risk ◽  
Differentiated Thyroid Cancer ◽  
Pooled Analysis ◽  
Case Control ◽  
Case Control Studies ◽  
Recreational Physical Activity ◽  
Thyroid Cancer Risk

Abstract 4638: Fine mapping of two GWAS at 9q22 and 14q13 associated with differentiated thyroid cancer risk

2015 ◽  
Author(s):  
catherine TCHEANDJIEU ◽  
Fabienne LESUEUR ◽  
Marie Sanchez ◽  
Therese TRUONG ◽  
Pascal GUENEL
Keyword(s):  
Thyroid Cancer ◽  
Cancer Risk ◽  
Fine Mapping ◽  
Differentiated Thyroid Cancer ◽  
Thyroid Cancer Risk
Sign in / Sign up

Export Citation Format

Share Document