The Effect of Surgeon Experience on the Detection of Metastatic Lymph Nodes in the Central Compartment and the Pathologic Features of Clinically Unapparent Metastatic Lymph Nodes: What Are We Missing When We Don't Perform a Prophylactic Dissection of Central Compartment Lymph Nodes in Papillary Thyroid Cancer?

Thyroid ◽  
2014 ◽  
Vol 24 (8) ◽  
pp. 1282-1288 ◽  
Author(s):  
Sophie Scherl ◽  
Saral Mehra ◽  
Jason Clain ◽  
Laura L. Dos Reis ◽  
Mark Persky ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Lymph Nodes ◽  
Papillary Thyroid Cancer ◽  
Central Compartment ◽  
Papillary Thyroid ◽  
Metastatic Lymph Nodes ◽  
Metastatic Lymph ◽  
Pathologic Features ◽  
Surgeon Experience

Ultrasound-guided percutaneous ethanol injection in papillary thyroid cancer metastatic lymph-nodes

Endocrine ◽  
2014 ◽  
Vol 47 (2) ◽  
pp. 648-651 ◽  
Author(s):  
Guia Vannucchi ◽  
Danila Covelli ◽  
Michela Perrino ◽  
Simone De Leo ◽  
Laura Fugazzola
Keyword(s):  
Thyroid Cancer ◽  
Lymph Nodes ◽  
Papillary Thyroid Cancer ◽  
Percutaneous Ethanol Injection ◽  
Papillary Thyroid ◽  
Ultrasound Guided ◽  
Ethanol Injection ◽  
Metastatic Lymph Nodes ◽  
Metastatic Lymph

scholarly journals Lymphovascular invasion is associated with survival for papillary thyroid cancer

2016 ◽  
Vol 23 (7) ◽  
pp. 555-562 ◽  
Author(s):  
Lauren N Pontius ◽  
Linda M Youngwirth ◽  
Samantha M Thomas ◽  
Randall P Scheri ◽  
Sanziana A Roman ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Lymph Nodes ◽  
Papillary Thyroid Cancer ◽  
Lymphovascular Invasion ◽  
Distant Metastases ◽  
Cox Proportional Hazards Model ◽  
Papillary Thyroid ◽  
Metastatic Lymph Nodes ◽  
Cancer Data ◽  
Metastatic Lymph

Data are limited regarding the association between tumor lymphovascular invasion and survival for patients with papillary thyroid cancer (PTC). This study sought to examine lymphovascular invasion as an independent prognostic factor for patients with PTC undergoing thyroid resection. The National Cancer Data Base (2010–2011) was queried for patients with PTC who underwent total thyroidectomy or lobectomy. Patients were classified into two groups based on the presence/absence of lymphovascular invasion. Demographic, clinical and pathological features were evaluated for all patients. A Cox proportional hazards model was utilized to identify factors associated with survival. Results show that 45,415 patients met inclusion criteria; 11.6% had lymphovascular invasion. Patients with lymphovascular invasion were more likely to have larger tumors (2.8cm vs 1.5cm,P<0.01), metastatic lymph nodes (74.1% vs 32.5%,P<0.01), and distant metastases (3.0% vs 0.5%,P<0.01). They were also more likely to receive radioactive iodine (69.3% vs 44.9%,P<0.01). Unadjusted overall 5-year survival was lower for patients who had tumors with lymphovascular invasion (86.6% vs 94.5%) (log-rankP<0.01). After adjustment, increasing patient age (HR=1.06,P<0.01), male gender (HR=1.68,P<0.01), presence of metastatic lymph nodes (HR=1.77,P<0.01), distant metastases (HR=3.49,P<0.01), and lymphovascular invasion (HR=1.88,P<0.01) were associated with compromised survival. For patients with lymphovascular invasion, treatment with RAI was associated with reduced mortality (HR=0.43,P<0.01). The presence of lymphovascular invasion among patients with PTC is independently associated with compromised survival. Patients who have PTC with lymphovascular invasion should be considered higher risk, and adjuvant RAI should be more strongly considered.

Size Distribution of Metastatic Lymph Nodes with Extranodal Extension in Patients with Papillary Thyroid Cancer: A Pilot Study

Thyroid ◽  
2015 ◽  
Vol 25 (2) ◽  
pp. 238-241 ◽  
Author(s):  
Erin H. Alpert ◽  
Bruce M. Wenig ◽  
Eliza H. Dewey ◽  
Henry K. Su ◽  
Laura Dos Reis ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Pilot Study ◽  
Lymph Nodes ◽  
Size Distribution ◽  
Papillary Thyroid Cancer ◽  
Papillary Thyroid ◽  
Metastatic Lymph Nodes ◽  
Extranodal Extension ◽  
Metastatic Lymph
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