Serum Thyroglobulin Improves the Sensitivity of the McGill Thyroid Nodule Score for Well-Differentiated Thyroid Cancer

Thyroid ◽  
2014 ◽  
Vol 24 (5) ◽  
pp. 852-857 ◽  
Author(s):  
Patrick Scheffler ◽  
Veronique I. Forest ◽  
Rebecca Leboeuf ◽  
Anca V. Florea ◽  
Michael Tamilia ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Thyroid Nodule ◽  
Differentiated Thyroid Cancer ◽  
Serum Thyroglobulin ◽  
Well Differentiated

scholarly journals Rapid thyroid nodule growth is not a marker for well-differentiated thyroid cancer

2015 ◽  
Vol 13 (1) ◽  
Author(s):  
Claudius Falch ◽  
Steffen Axt ◽  
Bettina Scuffi ◽  
Alfred Koenigsrainer ◽  
Andreas Kirschniak ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Thyroid Nodule ◽  
Differentiated Thyroid Cancer ◽  
Nodule Growth ◽  
Well Differentiated

Serum thyroglobulin levels in patients with well-differentiated thyroid cancer during suppression therapy: study on 429 patients

1985 ◽  
Vol 10-10 (5-6) ◽  
Author(s):  
MariaElisa Girelli ◽  
Benedetto Busnardo ◽  
Renato Amerio ◽  
Giorgio Scotton ◽  
Dario Casara ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Differentiated Thyroid Cancer ◽  
Serum Thyroglobulin ◽  
Well Differentiated

McGill Thyroid Nodule Score in Differentiating Benign and Malignant Pediatric Thyroid Nodules: A Pilot Study

2017 ◽  
Vol 157 (4) ◽  
pp. 589-595 ◽  
Author(s):  
Michael Canfarotta ◽  
Douglas Moote ◽  
Christine Finck ◽  
Rebecca Riba-Wolman ◽  
Shefali Thaker ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Pilot Study ◽  
Thyroid Carcinoma ◽  
Thyroid Nodule ◽  
Differentiated Thyroid Cancer ◽  
Chart Review ◽  
Thyroid Nodules ◽  
Papillary Thyroid ◽  
Well Differentiated ◽  
Indeterminate Cytology

Objective The McGill Thyroid Nodule Score (MTNS) is a preoperative tool used to predict the risk for well-differentiated thyroid cancer given a specific nodule in adults. We evaluated the clinical utility of a modified pediatric MTNS with children and adolescents. Study Design Case series with chart review. Setting Tertiary care children’s hospital. Subjects and Methods This is a retrospective chart review of 46 patients ≤18 years of age presenting with a solitary or dominant thyroid nodule treated with surgical resection between September 2008 and December 2015. The cumulative MTNS for each nodule was calculated and compared with the final pathology. Results Of 46 patients, 10 (21.7%) were diagnosed with well-differentiated thyroid cancer (80% papillary thyroid carcinoma, 10% follicular variant of papillary thyroid carcinoma, 10% follicular thyroid carcinoma). Malignant nodules were associated with a greater mean MTNS (benign, 5.72 ± 3.03; malignant, 16 ± 3.13; P < .05). The sensitivity, specificity, and positive predictive value of malignancy were 100%, 94.4%, and 83.3% for scores ≥10 and 80%, 100%, and 100% for scores ≥11, respectively. In nodules with indeterminate cytology (Bethesda III and IV), the pediatric MTNS showed good differentiation between benign and malignant disease, with mean scores of 7.95 and 12.5, respectively ( P = .006). Conclusion This pilot study suggests that a comprehensive scoring system may help assess the risk of malignancy in pediatric thyroid nodules and differentiate nodules with indeterminate cytology into higher- and lower-risk categories. Given these findings, larger, multi-institutional studies are warranted.

The role of preoperative serum thyroglobulin values in the diagnosis of differentiated thyroid cancer

2017 ◽  
Author(s):  
Blertina Dyrmishi ◽  
Taulant Olldashi ◽  
Ema Lumi ◽  
Entela Puca ◽  
Dorina Ylli ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Differentiated Thyroid Cancer ◽  
Serum Thyroglobulin ◽  
Preoperative Serum
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