scholarly journals Subclinical Hypothyroidism in Pregnancy: Intellectual Development of Offspring

Thyroid ◽  
2011 ◽  
Vol 21 (10) ◽  
pp. 1143-1147 ◽  
Author(s):  
Hossein Ghorbani Behrooz ◽  
Maryam Tohidi ◽  
Yadollah Mehrabi ◽  
Ebrahim Ghorbani Behrooz ◽  
Mehdi Tehranidoost ◽  
...  
Keyword(s):  
Subclinical Hypothyroidism ◽  
Intellectual Development ◽  
In Pregnancy

scholarly journals Overt and subclinical hypothyroidism among Bangladeshi pregnant women and its effect on fetomaternal outcome

2015 ◽  
Vol 40 (2) ◽  
pp. 52-57 ◽  
Author(s):  
M Sharmeen ◽  
PA Shamsunnahar ◽  
TR Laita ◽  
SB Chowdhury
Keyword(s):  
Adverse Effects ◽  
Pregnant Women ◽  
Subclinical Hypothyroidism ◽  
Thyroid Dysfunction ◽  
Perinatal Outcomes ◽  
Fetal Outcome ◽  
Thyroid Stimulating Hormone ◽  
Overt Hypothyroidism ◽  
Adequate Treatment ◽  
In Pregnancy

Objectives: Thyroid disorders are among the common endocrine problems in pregnant women. It is now well established that not only overt but subclinical thyroid dysfunction also has adverse effects on maternal and fetal outcome. There are few data from Bangladesh about the prevalence of thyroid dysfunction in pregnancy. With this background, this study aims to find out thyroid dysfunction (both overt and subclinical hypothyroidism) in pregnancy and its impact on obstetrical outcome.Methods: We studied the evaluation of 50 admitted pregnancies corresponding to 29 women with subclinical hypothyroidism and rest 21 was overt hypothyroidism. Detailed history and examination were performed. Apart from routine obstetrical investigations, Thyroid Stimulating Hormone (TSH) estimation was done. Their obstetrical and perinatal outcomes were noted.Results: Overt hypothyroidism was significantly (p<0.05) higher in 25 to 44 years age group. However two and three abortions were significantly (p<0.05) higher in overt hypothyroidism patients. In sub clinical hypothyroidism 86.2% conceived firstly within 2 years and 66.7% in overt hypothyroidism patients conceived firstly in between 3 to 5 years after marriage. Overt hypothyroids were prone to have pregnancy-induced hypertension 42.9%, intrauterine growth restriction (P=0.001) and gestational diabetes (38.1%) as compared to subclinical cases. Neonatal complications were significantly more in overt hypothyroidism group. Mean TSH level was significantly (p<0.05) higher in overt hypothyroidism patients but mean FT4 level was almost similar in both groups. Majority of the patient underwent caesarean section in both groups due to associated medical and obstetrical complications. None of the babies showed hypothyroidism by cord blood tests. In this analysis our results showed that overt hypothyroidism among Bangladeshi pregnant women are associated with more maternal complication & adverse parental outcome than subclinical hypothyroidism. The adequate treatment of hypothyroidism during gestation minimizes risks and generally, makes it possible for pregnancies to be carried to term without complications. Significant adverse effects on maternal and fetal outcome were seen emphasizing the importance of routine antenatal thyroid screening.Bangladesh Med Res Counc Bull 2014; 40 (2): 52-57

scholarly journals Treatment of Subclinical Hypothyroidism or Hypothyroxinemia in Pregnancy

2017 ◽  
Vol 72 (8) ◽  
pp. 464-465
Author(s):  
Brian M. Casey ◽  
Elizabeth A. Thom ◽  
Alan M. Peaceman ◽  
Michael W. Varner ◽  
Yoram Sorokin ◽  
...  
Keyword(s):  
Subclinical Hypothyroidism ◽  
In Pregnancy

Study for optimal dose determination of levothyroxine in subclinical hypothyroidism in pregnancy

2016 ◽  
Vol 13 (3) ◽  
pp. 126
Author(s):  
Jayanta Chakraborty ◽  
Semanti Chakraborty ◽  
Ankan Bandopadhay
Keyword(s):  
Subclinical Hypothyroidism ◽  
Optimal Dose ◽  
Dose Determination ◽  
In Pregnancy

scholarly journals Prevalence of thyroid disorders in pregnancy

2018 ◽  
Vol 7 (9) ◽  
pp. 3493
Author(s):  
Sangeeta Pahwa ◽  
Sabia Mangat
Keyword(s):  
Pregnant Women ◽  
Subclinical Hypothyroidism ◽  
First Trimester ◽  
Antenatal Clinic ◽  
Fetal Outcome ◽  
Overt Hypothyroidism ◽  
Thyroid Disorders ◽  
Subclinical Hyperthyroidism ◽  
Thyroid Screening ◽  
In Pregnancy

Background: Thyroid disorders are among the common endocrine problems in pregnant women. Often overlooked in pregnancy due to nonspecific symptoms and hyper-metabolic state of pregnancy. Western literature shows prevalence of hypothyroidism in pregnancy as 2.5% and hypothyroidism as 0.1-0.4%. There is paucity of data on prevalence of thyroid disorders in India pregnant population. This study was carried out to know prevalence of thyroid disorders in pregnant women in Indian population.Methods: One hundred pregnant women attending antenatal clinic in first trimester were registered. Detailed history and examination was done. Apart from routine basic and obstetrical investigations, TSH, FT3 and FT4 level estimation was done.Results: Prevalence of thyroid dysfunction was high in this study in first trimester pregnant women, with subclinical hypothyroidism in 6%, overt hypothyroidism in 2%, subclinical hyperthyroidism 2 % and overt hyperthyroidism 0%.Conclusions: Prevalence of thyroid disorders, especially subclinical hypothyroidism (6%), overt hypothyroidism (2%) and subclinical hyperthyroidism (2%) was high. To prevent adverse effects on maternal and fetal outcome, we are emphasizing the importance of routine antenatal thyroid screening.

scholarly journals Variation in treatment practices for subclinical hypothyroidism in pregnancy: US national assessment

2019 ◽  
Author(s):  
Spyridoula Maraka ◽  
Raphael Mwangi ◽  
Xiaoxi Yao ◽  
Lindsey R Sangaralingham ◽  
Naykky M Singh Ospina ◽  
...  
Keyword(s):  
Subclinical Hypothyroidism ◽  
National Assessment ◽  
Treatment Practices ◽  
In Pregnancy

Maternale Schilddrüsenfunktionsstörung: schlauere Kinder durch L-Thyroxin?

2017 ◽  
Vol 221 (03) ◽  
pp. 105-106
Keyword(s):  
Subclinical Hypothyroidism ◽  
Sich Eine ◽  
Al Treatment ◽  
In Pregnancy

Casey BM et al. Treatment of Subclinical Hypothyroidism or Hypothyroxinemia in Pregnancy. N Engl J Med 2017; 376: 815–825 Kommentar zur Studie: David S. Cooper, Elizabeth N. Pearce: Subclinical Hypothyroidism and Hypothyroxinemia in Pregnancy – Still Nos Answers. N Engl J Med 2017; 376: 876–877 Wirkt sich eine subklinische Unterfunktion der Schilddrüse während der Schwangerschaft ungünstig auf die neuropsychologische Entwicklung des ungeborenen Kindes aus? Diese Frage wird in der Literatur kontrovers diskutiert. Auch der Nutzen eines routinemäßigen pränatalen Screenings sowie einer maternalen Hormonsubstitution ist unklar.

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