scholarly journals The Most Commonly Occurring Papillary Thyroid Cancer in the United States Is Now a Microcarcinoma in a Patient Older than 45 Years

Thyroid ◽  
2011 ◽  
Vol 21 (3) ◽  
pp. 231-236 ◽  
Author(s):  
David T. Hughes ◽  
Megan R. Haymart ◽  
Barbra S. Miller ◽  
Paul G. Gauger ◽  
Gerard M. Doherty
Keyword(s):  
United States ◽  
Thyroid Cancer ◽  
Papillary Thyroid Cancer ◽  
The United States ◽  
Papillary Thyroid

Utilization of total thyroidectomy for papillary thyroid cancer in the United States

Surgery ◽  
2007 ◽  
Vol 142 (6) ◽  
pp. 906-913.e2 ◽  
Author(s):  
Karl Y. Bilimoria ◽  
David J. Bentrem ◽  
John G. Linn ◽  
Andrew Freel ◽  
Jen Jen Yeh ◽  
...  
Keyword(s):  
United States ◽  
Thyroid Cancer ◽  
Total Thyroidectomy ◽  
Papillary Thyroid Cancer ◽  
The United States ◽  
Papillary Thyroid

scholarly journals Risk of second primary papillary thyroid cancer among adult cancer survivors in the United States, 2000-2015

2020 ◽  
Vol 64 ◽  
pp. 101664 ◽  
Author(s):  
Sara J. Schonfeld ◽  
Lindsay M. Morton ◽  
Amy Berrington de González ◽  
Rochelle E. Curtis ◽  
Cari M. Kitahara
Keyword(s):  
United States ◽  
Thyroid Cancer ◽  
Cancer Survivors ◽  
Papillary Thyroid Cancer ◽  
The United States ◽  
Second Primary ◽  
Papillary Thyroid ◽  
Adult Cancer Survivors

scholarly journals A Birth Cohort Analysis of the Incidence of Papillary Thyroid Cancer in the United States, 1973–2004

Thyroid ◽  
2009 ◽  
Vol 19 (10) ◽  
pp. 1061-1066 ◽  
Author(s):  
Cairong Zhu ◽  
Tongzhang Zheng ◽  
Briseis A. Kilfoy ◽  
Xuesong Han ◽  
Shuangge Ma ◽  
...  
Keyword(s):  
United States ◽  
Thyroid Cancer ◽  
Birth Cohort ◽  
Papillary Thyroid Cancer ◽  
Cohort Analysis ◽  
The United States ◽  
Papillary Thyroid ◽  
Birth Cohort Analysis

scholarly journals Impact of Overweight and Obesity on US Papillary Thyroid Cancer Incidence Trends (1995–2015)

2019 ◽  
Vol 112 (8) ◽  
pp. 810-817 ◽  
Author(s):  
Cari M Kitahara ◽  
Ruth M Pfeiffer ◽  
Julie A Sosa ◽  
Meredith S Shiels
Keyword(s):  
United States ◽  
Thyroid Cancer ◽  
Papillary Thyroid Cancer ◽  
The United States ◽  
Incidence Rates ◽  
Overweight And Obesity ◽  
Study Cohort ◽  
Papillary Thyroid ◽  
Incidence Trends ◽  
Hazard Ratios

Abstract Background Since the early 1980s, papillary thyroid cancer (PTC) incidence rates and the prevalence of obesity, a risk factor for PTC, have increased substantially in the United States. We estimated the proportion of PTC incidence in the United States attributable to overweight and obesity during 1995–2015. Methods National Institutes of Health-AARP Diet and Health Study cohort data (n = 457 331 participants, 50–71 years and cancer-free at baseline) were used to estimate multivariable-adjusted hazard ratios (HRs) for PTC across body mass index categories. Population attributable fractions (PAFs) were calculated using estimated hazard ratios and annual overweight and obesity prevalence estimates from the National Health Interview Survey. PAF estimates were combined with Surveillance, Epidemiology, and End Results-13 data to calculate annual percent changes in PTC incidence rates attributable (and unrelated) to overweight and obesity. Results Overweight (25.0–29.0 kg/m2) and obesity (≥30.0 kg/m2) were associated with 1.26-fold (95% confidence interval [CI] = 1.05- to 1.52-fold) and 1.30-fold (95% CI = 1.05- to 1.62-fold) increased risks of PTC, respectively, and nearly threefold (HR = 2.93, 95% CI = 1.25 to 6.87) and greater than fivefold (HR = 5.42, 95% CI = 2.24 to 13.1) increased risks of large (>4 cm) PTCs compared with normal weight (18.5–24.9 kg/m2). During 1995–2015, PAF estimates for overweight and obesity increased from 11.4% to 16.2% for all PTCs and from 51.4% to 63.2% for large PTCs. Overweight or obesity accounted for 13.6% and 57.8% of the annual percent changes in total (5.9%/y) and large (4.5%/y) PTC incidence rates, respectively, during 1995–2015. Conclusions Overweight and obesity may have contributed importantly to the rapid rise in PTC incidence during 1995–2015. By 2015, we estimate that one of every six PTCs diagnosed among adults 60 years or older, including nearly two-thirds of large PTCs, were attributable to overweight and obesity.

scholarly journals Splenectomy for Solitary Splenic Metastasis in Recurrent Papillary Thyroid Cancer. A Case Report and Literature Review

2020 ◽  
Vol 2020 ◽  
pp. 1-5
Author(s):  
Antonio Maffuz-Aziz ◽  
Gabriel Garnica ◽  
Silvia López-Hernández ◽  
Janet Pineda-Diaz ◽  
Javier Baquera-Heredia ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Papillary Thyroid Cancer ◽  
Lung Metastases ◽  
The United States ◽  
Central Neck Dissection ◽  
Splenic Metastasis ◽  
Papillary Thyroid ◽  
Rare Manifestation ◽  
Tall Cell

Thyroid cancer is the most common endocrine malignancy, presenting with 23 500 new cases per year in the United States. About 7-23% of the patients will present recurrent metastases disease during follow-up. The classic variant of papillary carcinoma is less aggressive compared to its other variants like diffuse sclerosing, tall cell or columnar cell, and insular variants, and the sites to which this metastasizes is already well identified. Metastasis to the spleen is an extremely rare manifestation of papillary thyroid cancer. To date, only 3 cases have been reported in the literature. Herein, we present a 52-year-old male, who developed spleen metastases, 2.4 years after total thyroidectomy and central neck dissection followed by radioactive iodine ablation and seven months after treatment with sorafenib for lung metastases. The splenic lesion was detected in surveillance studies. This case highlights that splenic metastasis, although rare, may occur even in a patient with a locoregional and systemic controlled thyroid cancer and that it can be treated safely with surgical resection.

scholarly journals Patterns of Cervical Lymph Node Metastases in Primary and Recurrent Papillary Thyroid Cancer

2011 ◽  
Vol 2011 ◽  
pp. 1-5 ◽  
Author(s):  
Neda Ahmadi ◽  
Ameet Grewal ◽  
Bruce J. Davidson
Keyword(s):  
Thyroid Cancer ◽  
Papillary Thyroid Cancer ◽  
Recurrent Disease ◽  
The United States ◽  
Common Type ◽  
Lateral Neck ◽  
Papillary Thyroid ◽  
Level Ii ◽  
Node Metastases ◽  
Level I

The incidence of thyroid cancer is rising in the United States with papillary thyroid cancer (PTC) being the most common type. We performed a retrospective study of 49 patients with PTC who underwent 57 lateral neck dissections (NDs). The extent of NDs varied, but 29 of 57 (51%) consisted of levels II–V. Twelve of 57 (21%) NDs consisted of levels I–V. Twelve of 57 (21%) NDs consisted of levels II–IV. One of 57 (1.8%) necks involved only levels I–IV. One of 57(1.8%) necks involved only levels I–V. One of 57(1.8%) necks involved only levels III–V. Two (3.5%) double-level (III–IV) neck surgeries were also performed. Metastatic PTC adenopathy was confirmed pathologically in 2%-level-I, 45%-level-II, 57%-level-III, 60%-level-IV, and 22%-level-V necks. Level-V was positive in 21% of primary and 24% of recurrent groups (). Comparing primary and recurrent disease, there was no difference in nodal distribution or frequency for levels I, II, III, and V. Level-IV was more common in the recurrent cases (). Based on the pathologic distribution of nodes, dissection should routinely include levels II–IV and extend to level-V in primary and recurrent cases. Our data does not suggest routine dissection of level-I.

scholarly journals Thyroid Ultrasound and the Increase in Diagnosis of Low-Risk Thyroid Cancer

2018 ◽  
Vol 104 (3) ◽  
pp. 785-792 ◽  
Author(s):  
Megan R Haymart ◽  
Mousumi Banerjee ◽  
David Reyes-Gastelum ◽  
Elaine Caoili ◽  
Edward C Norton
Keyword(s):  
Thyroid Cancer ◽  
Papillary Thyroid Cancer ◽  
Cancer Incidence ◽  
The United States ◽  
Low Risk ◽  
Thyroid Ultrasound ◽  
Papillary Thyroid ◽  
Initial Imaging ◽  
Thyroid Cancer Incidence ◽  
Over Time

Abstract Context Thyroid cancer incidence increased with the greatest change in adults aged ≥65 years. Objective To determine the relationship between area-level use of imaging and thyroid cancer incidence over time. Design, Setting and Participants Longitudinal imaging patterns in Medicare patients aged ≥65 years residing in Surveillance, Epidemiology, and End Results (SEER) regions were assessed in relationship to differentiated thyroid cancer diagnosis in patients aged ≥65 years included in SEER-Medicare. Linear mixed-effects modeling was used to determine factors associated with thyroid cancer incidence over time. Multivariable logistic regression was used to determine patient characteristics associated with receipt of thyroid ultrasound as initial imaging. Main Outcome Measure Thyroid cancer incidence. Results Between 2002 and 2013, thyroid ultrasound use as initial imaging increased (P < 0.001). Controlling for time and demographics, use of thyroid ultrasound was associated with thyroid cancer incidence (P < 0.001). Findings persisted when cohort was restricted to papillary thyroid cancer (P < 0.001), localized papillary thyroid cancer (P = 0.004), and localized papillary thyroid cancer with tumor size ≤1 cm (P = 0.01). Based on our model, from 2003 to 2013, at least 6594 patients aged ≥65 years were diagnosed with thyroid cancer in the United States due to increased use of thyroid ultrasound. Thyroid ultrasound as initial imaging was associated with female sex and comorbidities. Conclusion Greater thyroid ultrasound use led to increased diagnosis of low-risk thyroid cancer, emphasizing the need to reduce harms through reduction in inappropriate ultrasound use and adoption of nodule risk stratification tools.

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