Histopathologic Diagnosis of Thyroid Tuberculosis

Thyroid ◽  
2009 ◽  
Vol 19 (9) ◽  
pp. 983-986 ◽  
Author(s):  
Selver Ozekinci ◽  
Bülent Mizrak ◽  
Gülbin Saruhan ◽  
Senem Senturk
2021 ◽  
Vol 8 (2) ◽  
pp. 107-123
Author(s):  
Dieter Metze ◽  
Heiko Traupe ◽  
Kira Süßmuth

Ichthyoses are inborn keratinization disorders affecting the skin only (non-syndromic) or are associated with diseases of internal organs (syndromic). In newborns, they can be life-threatening. The identification of the gene defects resulted in reclassification and a better understanding of the pathophysiology. Histopathologic patterns include orthohyperkeratosis with a reduced or well-developed stratum granulosum, hyperkeratosis with ortho- and parakeratosis with preserved or prominent stratum granulosum, and epidermolytic ichthyosis. Another pattern features “perinuclear vacuoles and binucleated keratinocytes”, which is associated with keratin mutations. Some ichthyoses are histologically defined by psoriasis-like features, and distinct subtypes show follicular hyperkeratosis. In addition to histological and immunohistochemical methods, these patterns allow a better histopathologic diagnosis.


Animals ◽  
2021 ◽  
Vol 11 (3) ◽  
pp. 883
Author(s):  
Massimo Vignoli ◽  
Roberto Tamburro ◽  
Andrea Felici ◽  
Francesca Del Signore ◽  
Annalisa Dettori ◽  
...  

Diagnosis of thoracic lesions on the basis of history and physical examination is often challenging. Diagnostic imaging is therefore of paramount importance in this field. Radiology has traditionally been considered the diagnostic procedure of choice for these diseases. Nevertheless, it is often not possible to differentiate inflammatory/infectious lesions from neoplastic diseases. A correct cytological and histopathologic diagnosis is therefore needed for an accurate diagnosis and subsequent prognostic and therapeutic approach. In human medicine, Computed Tomography (CT) and CT-guided biopsy are used in the presence of lesions which are not adequately diagnosed with other procedures. In the present study, thoracic lesions from 52 dogs and 10 cats of different sex, breed and size underwent both CT-guided fine-needle aspiration (FNAB) and tissue-core biopsy (TCB). Clinical examination, hematobiochemical analysis and chest radiography were performed on all animals. In this study, 59 of 62 histopathological samples were diagnostic (95.2%). Cytology was diagnostic in 43 of 62 samples (69.4%). General sensitivity, accuracy and PPV for FNAB and TCB were 67.7%, 67.7% and 100% and 96.7%, 95.2% and 98.3%, respectively. Combining the two techniques, the overall mean accuracy for diagnosis was 98.4%. Nineteen of 62 cases showed complications (30.6%). Mild pneumothorax was seen in 16 cases, whereas mild hemorrhage occurred in three cases. No major complications were encountered. CT-guided FNAB cytology can be considered a useful and reliable technique, especially for small lesions or lesions located close to vital organs and therefore dangerous to biopsy in other way.


1989 ◽  
Vol 3 (2) ◽  
pp. 187-204 ◽  
Author(s):  
John Anastasi ◽  
Mitchell A. Bitter ◽  
James W. Vardiman

2014 ◽  
Vol 9 (1) ◽  
pp. 227-230 ◽  
Author(s):  
GAO-YI YANG ◽  
DAN ZHAO ◽  
WEN-ZHI ZHANG ◽  
JUN MENG ◽  
JUN LI ◽  
...  

1994 ◽  
Vol 8 (1) ◽  
pp. 1-6 ◽  
Author(s):  
Scott Jeffrey Trimas ◽  
Scott P. Stringer

The histopathologic diagnosis of nasal and paranasal sinus masses may be problematic. Traditionally, a biopsy through an external ethmoidectomy or Caldwell-Luc procedure has been required. The advent of nasal endoscopy provides an alternative method of obtaining tissue. The diagnostic evaluations of 57 cases of nasal or paranasal sinus masses, seen from 1985 through 1991, were reviewed. The use of nasal endoscopy in the diagnosis of nasal and paranasal sinus masses was associated with decreased morbidity as compared to more traditional approaches. Potential surgical approaches were not violated prior to definitive treatment. Representative cases will be presented illustrating changes in management by using nasal endoscopes.


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