Targeting Epidermal Growth Factor Receptor 1 Signaling in Human Thyroid-Stimulating Hormone–Independent Thyroid Carcinoma FRO Cells Results in a More Chemosensitive and Less Angiogenic Phenotype

Thyroid ◽  
2009 ◽  
Vol 19 (6) ◽  
pp. 629-637 ◽  
Author(s):  
Matteo Landriscina ◽  
Annamaria Piscazzi ◽  
Annarita Fabiano ◽  
Francesca Maddalena ◽  
Eleonora Costantino ◽  
...  
Keyword(s):  
Epidermal Growth Factor Receptor ◽  
Growth Factor ◽  
Epidermal Growth Factor ◽  
Thyroid Carcinoma ◽  
Growth Factor Receptor ◽  
Thyroid Stimulating Hormone ◽  
Human Thyroid ◽  
Epidermal Growth ◽  
Stimulating Hormone

Epidermal growth factor receptor gene mutations in papillary thyroid carcinoma

2008 ◽  
Vol 124 (11) ◽  
pp. 2744-2749 ◽  
Author(s):  
Katsuhiro Masago ◽  
Ryo Asato ◽  
Shiro Fujita ◽  
Shigeru Hirano ◽  
Yoshihiro Tamura ◽  
...  
Keyword(s):  
Epidermal Growth Factor Receptor ◽  
Growth Factor ◽  
Papillary Thyroid Carcinoma ◽  
Epidermal Growth Factor ◽  
Thyroid Carcinoma ◽  
Receptor Gene ◽  
Growth Factor Receptor ◽  
Gene Mutations ◽  
Papillary Thyroid ◽  
Epidermal Growth

Epidermal growth factor receptor on human thyroid neoplasms

1988 ◽  
Vol 12 (5) ◽  
pp. 616-621 ◽  
Author(s):  
Hiroyuki Masuda ◽  
Akira Sugenoya ◽  
Shinya Kobayashi ◽  
Yoshio Kasuga ◽  
Futoshi Iida
Keyword(s):  
Epidermal Growth Factor Receptor ◽  
Growth Factor ◽  
Epidermal Growth Factor ◽  
Growth Factor Receptor ◽  
Thyroid Neoplasms ◽  
Human Thyroid ◽  
Epidermal Growth

scholarly journals Distribution and Prognostic Significance of Estrogen Receptor α (ERα), Estrogen Receptor β (ERβ), and Human Epidermal Growth Factor Receptor 2 (HER-2) in Thyroid Carcinoma

2020 ◽  
Vol 2020 ◽  
pp. 1-8
Author(s):  
Anjali Mishra ◽  
Niraj Kumari ◽  
Chandan Kumar Jha ◽  
Raouef Ahamed Bichoo ◽  
Shravan Kumar Mishra ◽  
...  
Keyword(s):  
Estrogen Receptor ◽  
Epidermal Growth Factor Receptor ◽  
Prognostic Factors ◽  
Growth Factor ◽  
Epidermal Growth Factor ◽  
Thyroid Carcinoma ◽  
Growth Factor Receptor ◽  
Human Epidermal Growth Factor ◽  
Her 2 ◽  
Epidermal Growth

Purpose. The primary aim of this study was to determine the incidence of estrogen receptor α (ERα), estrogen receptor β (ERβ), and human epidermal growth factor receptor 2 (HER-2) expression in various subtypes of thyroid carcinoma (TC) of follicular origin and the secondary aim was to correlate the expression with various clinicopathologic prognostic factors. Methods. Immunohistochemistry analysis was performed on archival paraffin-embedded tissue sections (1991–2016). ERα, ERβ, and HER-2 expressions were correlated with clinicopathologic prognostic factors, disease recurrence, and overall survival (OS). Results. A total of 264 TC patients were included in the study. Incidences of ERα, ERβ, and HER-2 were 8.1 vs 16.3 vs 13.9% p=0.15, 26.6 vs 11.5 vs 36.1% p=0.002, and 12.9 vs 2.9 vs 0% p=0.003 in papillary thyroid carcinoma (PTC), follicular thyroid carcinoma (FTC), and poorly differentiated thyroid carcinoma (PDTC), respectively. Overall ERα had significant correlation with distant metastases (0.038) and in case of PDTC with multicentricity p=0.037. ERβ had significant correlation with lymph node metastases p=0.023 in FTC. HER-2 correlated with tumor size p=0.027 only on univariate analysis. OS did not correlate with expression of any receptor. Conclusion. ERα, ERβ, and HER-2 have differential expression and prognostic implications in different TC subtypes.

scholarly journals Epidermal growth factor receptor status in anaplastic thyroid carcinoma

2006 ◽  
Vol 60 (8) ◽  
pp. 881-884 ◽  
Author(s):  
D. H. Lee ◽  
G. K. Lee ◽  
S.-y. Kong ◽  
M. C. Kook ◽  
S. K. Yang ◽  
...  
Keyword(s):  
Epidermal Growth Factor Receptor ◽  
Growth Factor ◽  
Epidermal Growth Factor ◽  
Thyroid Carcinoma ◽  
Growth Factor Receptor ◽  
Anaplastic Thyroid Carcinoma ◽  
Receptor Status ◽  
Epidermal Growth

scholarly journals IMMUNOHISTOCHEMICAL STUDY OF EPIDERMAL GROWTH FACTOR RECEPTOR AND ESTROGEN RECEPTOR IN HUMAN THYROID TUMORS

1993 ◽  
Vol 96 (5) ◽  
pp. 787-790_1,873 ◽  
Author(s):  
KATSUNARI YANE ◽  
OSAMU TANAKA ◽  
HIROSHI MIYAHARA ◽  
TAKASHI MATSUNAGA ◽  
YOSHITERU KITAHORI ◽  
...  
Keyword(s):  
Estrogen Receptor ◽  
Epidermal Growth Factor Receptor ◽  
Growth Factor ◽  
Epidermal Growth Factor ◽  
Immunohistochemical Study ◽  
Growth Factor Receptor ◽  
Human Thyroid ◽  
Thyroid Tumors ◽  
Epidermal Growth
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