No Evidence of Thyrotropin Receptor and GSα Gene Mutation in High Iodine Uptake Thyroid Carcinoma

Thyroid ◽  
2000 ◽  
Vol 10 (9) ◽  
pp. 761-765 ◽  
Author(s):  
I. Bourasseau ◽  
F. Savagner ◽  
P. Rodien ◽  
M. Duquenne ◽  
P. Reynier ◽  
...  
Keyword(s):  
Thyroid Carcinoma ◽  
Gene Mutation ◽  
Iodine Uptake ◽  
Thyrotropin Receptor ◽  
High Iodine ◽  
Gsα Gene

A Case of Hyperthyroidism due to Metastasis of a Thyroid Carcinoma

1979 ◽  
Vol 65 (6) ◽  
pp. 777-780 ◽  
Author(s):  
Alberto Turrin ◽  
Saro Oriana ◽  
Paolo Bonardi
Keyword(s):  
Bone Metastasis ◽  
Thyroid Carcinoma ◽  
Clinical Picture ◽  
Pulmonary Metastases ◽  
Iodine Uptake ◽  
Uptake Capacity ◽  
High Iodine ◽  
Repeated Administrations ◽  
Metabolic Radiotherapy

A case of hyperthyroidism, which developed in a patient affected by thyroid carcinoma a few days after thyroidectomy, is described. The symptomatology was caused by a bone metastasis at the left ischiopubic branch, which had a high iodine-uptake capacity and was sensitive to metabolic radiotherapy. Pulmonary metastases were also present; they had a distinct low affinity for iodine and showed no response to repeated administrations of 131I. The case is evaluated on the basis of the evolution of the clinical picture and the hormone dosages administered in a follow-up period of 3 years.

Follicular thyroid carcinoma due to a heterozygous gain of function mutation in thyrotropin receptor (TSHR)

2017 ◽  
Author(s):  
James Blackburn ◽  
Dinesh Giri ◽  
Senthil Seniappan ◽  
Mohammed Didi ◽  
Barbara Ciolka ◽  
...  
Keyword(s):  
Thyroid Carcinoma ◽  
Follicular Thyroid Carcinoma ◽  
Thyrotropin Receptor ◽  
Gain Of Function

Feline Thyroid Adenomas are in Part Associated with Mutations in the Gsα Gene and not with Polymorphisms Found in the Thyrotropin Receptor

Thyroid ◽  
2002 ◽  
Vol 12 (7) ◽  
pp. 571-575 ◽  
Author(s):  
Marijke E. Peeters ◽  
Elpetra P.M. Timmermans-Sprang ◽  
Jan A. Mol
Keyword(s):  
Thyrotropin Receptor ◽  
Gsα Gene ◽  
Thyroid Adenomas

scholarly journals A Japanese family with nonautoimmune hyperthyroidism caused by a novel heterozygous thyrotropin receptor gene mutation

2014 ◽  
Vol 75 (6) ◽  
pp. 749-753 ◽  
Author(s):  
Akie Nakamura ◽  
Shuntaro Morikawa ◽  
Hayato Aoyagi ◽  
Katsura Ishizu ◽  
Toshihiro Tajima
Keyword(s):  
Gene Mutation ◽  
Receptor Gene ◽  
Thyrotropin Receptor ◽  
Japanese Family

STUDIES OF IODINE METABOLISM IN ICELAND

1964 ◽  
Vol 46 (4) ◽  
pp. 679-683 ◽  
Author(s):  
W. D. Alexander ◽  
Th. Veiger Gudmundsson ◽  
M. M. Bluhm ◽  
R. McG. Harden
Keyword(s):  
Thyroid Gland ◽  
Iodine Content ◽  
Iodine Uptake ◽  
Hormone Production ◽  
High Iodine ◽  
Iodine Level ◽  
Iodine Metabolism ◽  
Inorganic Iodine

ABSTRACT The relation between plasma inorganic iodine level, thyroid clearance and absolute iodine uptake of the thyroid gland has been studied in Iceland and compared with results obtained in Glasgow using identical methods. In Iceland the plasma inorganic iodine (PII) is higher than in Glasgow due to the high iodine content of the diet and the thyroid clearance lower. This adjustment is, however, incomplete, relatively high PII levels being associated with a low thyroid clearance and a raised absolute uptake by the thyroid. There was no evidence of increased hormone production as reflected in the serum PBI.

Mild and severe congenital primary hypothyroidism in two patients by thyrotropin receptor (TSHR) gene mutation

2012 ◽  
Vol 25 (11-12) ◽  
Author(s):  
Veysel Nijat Baş ◽  
Hakan Cangul ◽  
Sebahat Yilmaz Agladioglu ◽  
Michaela Kendall ◽  
Semra Cetinkaya ◽  
...  
Keyword(s):  
Gene Mutation ◽  
Primary Hypothyroidism ◽  
Thyrotropin Receptor ◽  
Tshr Gene

scholarly journals Focal Bronchiectasis Causing Abnormal Pulmonary Radioiodine Uptake in a Patient with Well-Differentiated Papillary Thyroid Carcinoma

2012 ◽  
Vol 2012 ◽  
pp. 1-3
Author(s):  
Ash Gargya ◽  
Elizabeth Chua
Keyword(s):  
Papillary Thyroid Carcinoma ◽  
Thyroid Carcinoma ◽  
Radioactive Iodine ◽  
Differentiated Thyroid Carcinoma ◽  
Whole Body ◽  
Iodine Uptake ◽  
Papillary Thyroid ◽  
Radioiodine Uptake ◽  
Well Differentiated ◽  
Radioactive Iodine Uptake

Background. False-positive pulmonary radioactive iodine uptake in the followup of differentiated thyroid carcinoma has been reported in patients with certain respiratory conditions.Patient Findings. We describe a case of well-differentiated papillary thyroid carcinoma treated by total thyroidectomy and radioiodine ablation therapy. Postablation radioiodine whole body scan and subsequent diagnostic radioiodine whole body scans have shown persistent uptake in the left hemithorax despite an undetectable stimulated serum thyroglobulin in the absence of interfering thyroglobulin antibodies. Contrast-enhanced chest computed tomography has confirmed that the abnormal pulmonary radioiodine uptake correlates with focal bronchiectasis.Summary. Bronchiectasis can cause abnormal chest radioactive iodine uptake in the followup of differentiated thyroid carcinoma.Conclusions. Recognition of potential false-positive chest radioactive iodine uptake, simulating pulmonary metastases, is needed to avoid unnecessary exposure to further radiation from repeated therapeutic doses of radioactive iodine.

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