Evaluation of Routine Basal Serum Calcitonin Measurement for Early Diagnosis of Medullary Thyroid Carcinoma in Seven Hundred Seventy-Three Patients with Nodular Goiter

Thyroid ◽  
1999 ◽  
Vol 9 (6) ◽  
pp. 579-582 ◽  
Author(s):  
A. GÖKHAN ÖZGEN ◽  
FÜSUN HAMULU ◽  
FIRAT BAYRAKTAR ◽  
CANDEĞER YILMAZ ◽  
MEHMET TÜZÜN ◽  
...  
Keyword(s):  
Early Diagnosis ◽  
Thyroid Carcinoma ◽  
Medullary Thyroid Carcinoma ◽  
Nodular Goiter ◽  
Serum Calcitonin ◽  
Medullary Thyroid ◽  
Basal Serum

A cut-off value of basal serum calcitonin for detecting macroscopic medullary thyroid carcinoma

2014 ◽  
Vol 82 (4) ◽  
pp. 598-603 ◽  
Author(s):  
Hyemi Kwon ◽  
Won Gu Kim ◽  
Yun Mi Choi ◽  
Eun Kyung Jang ◽  
Min Ji Jeon ◽  
...  
Keyword(s):  
Thyroid Carcinoma ◽  
Medullary Thyroid Carcinoma ◽  
Serum Calcitonin ◽  
Medullary Thyroid ◽  
Basal Serum

scholarly journals Usefulness of preoperative serum calcitonin in patients with nodular thyroid disease without suspicious history or cytology for medullary thyroid carcinoma

2013 ◽  
Vol 57 (4) ◽  
pp. 312-316 ◽  
Author(s):  
Pedro Weslley Rosário ◽  
Gustavo Cancela Penna ◽  
Kamilla Brandão ◽  
Bárbara Érika Souza
Keyword(s):  
Thyroid Carcinoma ◽  
Medullary Thyroid Carcinoma ◽  
Multiple Endocrine Neoplasia ◽  
Multiple Endocrine Neoplasia Type ◽  
Serum Calcitonin ◽  
Medullary Thyroid ◽  
Endocrine Neoplasia ◽  
Preoperative Serum ◽  
History Of

OBJECTIVE: To evaluate the usefulness of preoperative serum calcitonin (sCT) in patients with nodular disease without suspicion of medullary thyroid carcinoma (MTC) in history or cytology. PATIENTS AND METHODS: sCT was measured before thyroidectomy in 494 patients with nodular disease who had no family history of MTC or multiple endocrine neoplasia type 2, and no cytological suspicion of MTC. RESULTS: Basal sCT was < 10 ng/mL in 482 patients and none of them had MTC. One patient with basal sCT > 100 pg/mL had MTC. Among the 11 patients with basal sCT between 10 and 100 pg/mL, MTC was diagnosed in only one. The two patients with MTC were submitted to total thyroidectomy, combined with elective lymph node dissection indicated exclusively based on hypercalcitoninemia, and sCT was undetectable after six months. CONCLUSIONS: Preoperative sCT is useful for the detection of sporadic MTC in patients with nodular disease, even in the absence of suspicious history or cytology.

scholarly journals Serum calcitonin negative Medullary thyroid carcinoma

2006 ◽  
Vol 4 (1) ◽  
Author(s):  
Michael Sand ◽  
Marcos Gelos ◽  
Daniel Sand ◽  
Falk G Bechara ◽  
Gerd Bonhag ◽  
...  
Keyword(s):  
Thyroid Carcinoma ◽  
Medullary Thyroid Carcinoma ◽  
Serum Calcitonin ◽  
Medullary Thyroid
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