Effectiveness of Preoperative Radioactive Iodine (131I) Therapy for Locally Advanced Papillary Thyroid Cancer: A Case Report

Thyroid ◽  
1998 ◽  
Vol 8 (12) ◽  
pp. 1113-1116 ◽  
Author(s):  
KIYOSHI SHINGU ◽  
SHINYA KOBAYASHI ◽  
SHIRO YOKOYAMA ◽  
TADAHIRO SHIMIZU ◽  
YOSHIO KASUGA ◽  
...  
2021 ◽  
Vol 2021 ◽  
pp. 1-8
Author(s):  
Khaled Ahmed Baagar ◽  
Buthina Ibrahim Alowainati

Familial nonmedullary thyroid cancer (FNMTC) represents 5–10% of NMTC cases. Many controversies are associated with the FNMTC, namely, the minimum required number of affected family members to define the condition, aggressiveness, prognosis, and treatment and screening recommendations. Moreover, the genetic basis of the FNMTC has not yet been identified. We report a family diagnosed with FNMTC and present a comprehensive literature review of the condition. The index case was a 26-year-old male who was diagnosed with locally advanced papillary thyroid cancer (PTC). Then, his family members became worried and asked for a neck ultrasound. Four of his six siblings, in addition to his father, were diagnosed with PTC. In addition, two of his cousins were diagnosed. The patient underwent total thyroidectomy with bilateral neck dissection, and he received 2 doses of radioactive iodine (100 mCi each). Furthermore, one of his siblings required a second surgery with repeated radioactive iodine therapy. The index case genetic screening and whole-exome sequencing did not show any abnormalities. Future genetic and clinical research should focus on kindred with 3 or more affected individuals for better identification of the FNMTC susceptibility genes and to better guide management and screening recommendations.


2020 ◽  
Vol 13 (3) ◽  
pp. 1364-1367
Author(s):  
Afaf Albattah ◽  
Yahia Imam ◽  
Ahmed Osman Saleh ◽  
Khalid Ahmed ◽  
Tarek Aboursheid ◽  
...  

Thyroid cancer is the most frequent endocrine neoplasm in the general population. Common risk factors include gender, radiation exposure, and genetic backgrounds. The association of papillary thyroid cancer and celiac disease has frequently been reported in the literature; however, the association of papillary thyroid cancer and thalassemia trait is rare. Likewise, the association of thalassemia major and celiac disease is also rare. We hereby report a unique case of papillary thyroid cancer in a patient with celiac disease and thalassemia trait.


2020 ◽  
Vol 60 ◽  
pp. 614-618
Author(s):  
Suwardjo Suwardjo ◽  
Widya Surya Avanti ◽  
Ery Kus Dwianingsih ◽  
Wirsma Arif Harahap ◽  
Sumadi Lukman Anwar

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