Resolution of Hyperthyroidism in a Pregnant Woman with Toxic Thyroid Nodule by Percutaneous Ethanol Injection

Thyroid ◽  
1995 ◽  
Vol 5 (6) ◽  
pp. 473-475 ◽  
Author(s):  
DONATELLA CORTELAZZI ◽  
DANIELA CASTAGNONE ◽  
BEATRICE TASSIS ◽  
ELISABETTA VENEGONI ◽  
ROBERTO RIVOLTA ◽  
...  
Keyword(s):  
Pregnant Woman ◽  
Thyroid Nodule ◽  
Percutaneous Ethanol Injection ◽  
Ethanol Injection

Severe Graves' Ophthalmopathy After Percutaneous Ethanol Injection in a Nontoxic Thyroid Nodule

Thyroid ◽  
2012 ◽  
Vol 22 (2) ◽  
pp. 210-213 ◽  
Author(s):  
Concetto Regalbuto ◽  
Rosario Le Moli ◽  
Vincenzo Muscia ◽  
Marco Russo ◽  
Riccardo Vigneri ◽  
...  
Keyword(s):  
Thyroid Nodule ◽  
Percutaneous Ethanol Injection ◽  
Ethanol Injection ◽  
Graves Ophthalmopathy

Is Percutaneous Ethanol Injection a Useful Alternative for the Treatment of the Cold Benign Thyroid Nodule? Five Years' Experience

Thyroid ◽  
1997 ◽  
Vol 7 (5) ◽  
pp. 699-704 ◽  
Author(s):  
NADIA CARACCIO ◽  
ORLANDO GOLETTI ◽  
PIERO VINCENZO LIPPOLIS ◽  
ARTURO CASOLARO ◽  
ENRICO CAVINA ◽  
...  
Keyword(s):  
Thyroid Nodule ◽  
Percutaneous Ethanol Injection ◽  
Ethanol Injection ◽  
Benign Thyroid Nodule ◽  
Benign Thyroid

scholarly journals Ultrasound Guided Percutaneous Ethanol Ablation of Benign Thyroid Nodule: A Study From a Tertiary Hospital in Eastern India

2021 ◽  
Vol 5 (Supplement_1) ◽  
pp. A873-A873
Author(s):  
Arjun Baidya ◽  
Saba Faiz ◽  
Ram Chandra Bhadra
Keyword(s):  
Thyroid Nodule ◽  
Thyroid Nodules ◽  
Response Rate ◽  
Percutaneous Ethanol Injection ◽  
Ultrasound Guided ◽  
Ethanol Ablation ◽  
Ethanol Injection ◽  
Benign Thyroid Nodule ◽  
Benign Thyroid

Abstract Introduction: Ultrasound guided percutaneous ethanol injection (PEI) of benign thyroid nodule is an easy and effective procedure particularly in cystic and predominantly cystic nodule. Aims: To evaluate efficacy and safety of PEI in managing purely cystic and mixed cystic and solid thyroid nodules. Materials and Methods: Patients of either sex presented with solitary purely cystic benign thyroid nodule, solitary benign mixed with predominantly cystic (>50% of total volume) thyroid nodule, solitary benign mixed with predominantly solid (>50% of total volume) thyroid nodule, solitary solid thyroid nodule were included in this study. Patients who had a nodule BETHESDA 3 and above, pregnancy, patients with critical or terminal illness, patients with other malignancies, multinodular lesions of thyroid, patients with raised T3, T4 and/ or suppressed TSH level were excluded from the study. One hundred sixty patients presenting with thyroid nodule were initially evaluated with thyroid function test and USG. Only those patients with euthyroid solitary thyroid nodules are subjected for fine needle aspiration (FNA). Nodules under BETHESDA 2 are considered for US guided percutaneous ethanol injection (PEI). One hundred twenty-three patients were excluded because of various reasons. Finally ethanol ablation was done in 37 patients. Benign, purely cystic and mixed thyroid nodules were aspirated under ultrasonography guidance. Sterile absolute alcohol (99.99%) (50% of volume aspirated/ maximum 10 ml) was injected and reviewed after 2, 5and 7 months. In case of solid nodule alcohol (50% of nodule volume) was injected. A reduction in volume is calculated at each follow up visit. An adequate response is considered as ≥50 percent reduction in size from baseline after 7 months. If the reduction is <50%, then a second session of absolute ethanol injection is given. Again, patients were similarly followed up after 2, 5 and 7 months. Results: Thirty seven patients underwent PEI. Thirty three patients were considered for final analysis (4 lost to follow up). Response rate of PEI for purely cystic nodule was 100.0% and the overall response rate for mixed nodule was 53.57%. None of the solid nodule responded to PEI even after second session. Among the responder in the mixed nodules, 93.33% responded after first session of PEI. Minor complications like headache occurred in 54.1% patients in the first session. Transient pain at injection site were complained by 86.5% and 37.8% patients in the first and second session respectively. Nausea and vomiting were complained by 18.9% and 16.2% patients in the first and second session respectively. Conclusions: PEI is an effective and safe for purely cystic and mixed thyroid nodules. It is a relatively safe and less invasive procedure from management of benign solitary cystic and mixed thyroid nodules.

Percutaneous ethanol injection therapy for autonomously functioning thyroid nodule

1996 ◽  
Vol 10 (2) ◽  
pp. 171-176 ◽  
Author(s):  
Kunihiro Nakada ◽  
Chietsugu Katoh ◽  
Kakuko Kanegae ◽  
Eriko Tsukamoto ◽  
Kazuo Itoh ◽  
...  
Keyword(s):  
Thyroid Nodule ◽  
Percutaneous Ethanol Injection ◽  
Injection Therapy ◽  
Ethanol Injection ◽  
Percutaneous Ethanol Injection Therapy ◽  
Ethanol Injection Therapy

Cold Benign Thyroid Nodule Volume Reduction Predictability After Percutaneous Ethanol Injection

2009 ◽  
Vol 53 (3) ◽  
pp. 292-296
Author(s):  
Vincenzo Nirchio ◽  
Francesco Nirchio ◽  
Umberto Crocetti ◽  
Paola Tizzani ◽  
Vincenzo Trischitta ◽  
...  
Keyword(s):  
Thyroid Nodule ◽  
Percutaneous Ethanol Injection ◽  
Volume Reduction ◽  
Ethanol Injection ◽  
Benign Thyroid Nodule ◽  
Nodule Volume ◽  
Benign Thyroid

scholarly journals Percutaneous Ethanol Injection in Combination with Laser Ablation for a 100 ml Partially Cystic Thyroid Nodule

2018 ◽  
Vol 2018 ◽  
pp. 1-3
Author(s):  
Roberto Negro ◽  
Gabriele Greco
Keyword(s):  
Laser Ablation ◽  
Thyroid Nodule ◽  
Percutaneous Ethanol Injection ◽  
Complete Disappearance ◽  
Ethanol Injection ◽  
Cystic Component

Until nonsurgical techniques like laser ablation (LA) or radiofrequency became available, patients suffering from large nodules with compressive symptoms were addressed to surgery. We describe the case of a 59-year-old woman with a large, partially cystic thyroid nodule having a volume of about 100 ml. As the patient refused surgery, despite her constant local discomfort, such large partially cystic nodule underwent several percutaneous ethanol injections (PEI) and then was submitted to LA. The combination of these two procedures allowed firstly complete disappearance of the cystic component and secondly a significant reduction of thyroid nodule, which finally measured 17 ml in volume (82% reduction compared to baseline). This case demonstrates that even in very large partially cystic nodules LA preceded by PEI represents a valid alternative to surgery.

Autonomous thyroid nodule and percutaneous ethanol injection

The Lancet ◽  
1991 ◽  
Vol 337 (8743) ◽  
pp. 743 ◽  
Author(s):  
Fabio Monzani ◽  
Orlando Goletti ◽  
Ferdinando De Negri ◽  
Paolo Del Guerra ◽  
Piero Vincenzo Lippolis ◽  
...  
Keyword(s):  
Thyroid Nodule ◽  
Percutaneous Ethanol Injection ◽  
Ethanol Injection ◽  
Autonomous Thyroid Nodule

scholarly journals Percutaneous Ethanol Injection as Treatment for Thyroid Cystic Nodules

2021 ◽  
Vol 5 (Supplement_1) ◽  
pp. A947-A947
Author(s):  
Paola Rios ◽  
Jonathan Ambut ◽  
Alex Manzano
Keyword(s):  
Risk Factors ◽  
Thyroid Cancer ◽  
Thyroid Nodule ◽  
Percutaneous Ethanol Injection ◽  
Definitive Treatment ◽  
Thyroid Ultrasound ◽  
Thyroid Lobe ◽  
Invasive Approach ◽  
Ethanol Injection

Abstract Background: Thyroid cystic nodules are common and frequently benign. Aspiration of thyroid cyst decreases compression symptoms and volume. However, they commonly recur, and usually, surgery is required for definitive treatment. A less invasive approach, done less frequent, is percutaneous ethanol injection (PEI), which has shown fewer recurrences than simple aspiration and is well-tolerated with few side effects. We present 2 patients that where treated in our clinic with PEI. Clinical Case: 41-year-old female with a history of primary hypothyroidism on Levothyroxine, with neck discomfort, and no risk factors for thyroid cancer had a cystic thyroid nodule 1.5 x 1.8 x 2.8 cm over the right thyroid lobule. Cytology results reported as Bethesda II. One year later, her thyroid nodule was 1.9 x 2.6 x 3.3 cm. Underwent FNA and 6 cc of dark brown liquid was drained from the cyst which was reported again as Bethesda II. The patient was monitored with thyroid ultrasound after a year, and the cystic nodule was 2.2 x 2.9 x 3.1 cm. PEI was decided as the next approach. After six cc was aspired, 0.5 cc of desiccated ethanol was injected into the remained cystic. Eight months after PEI, cystic size was 0.7 x 0.9 x 0.8 cm. The second case is a 40-year-old female who presented complaining of neck discomfort without changes in her voice. The patient did not have any risk factors for thyroid cancer. Thyroid ultrasound was done, which showed a 2.3 x 2.7 x 3.3 cm cyst on her right thyroid lobe. PEI was arranged and 9 cc of dark fluid was aspirated with a posterior injection of 0.5 cc of desiccated ethanol. Symptoms resolved, and the patient was lost to follow up. Five years later, she was seen again. Neck ultrasound showed a cyst of 0.4 x 0.6 x 0.8 cm on her right thyroid lobe. Neither of the two patients had a side effect associated, and the procedure was well tolerated. Conclusions: Percutaneous ethanol injection is a good alternative in the treatment for cystic thyroid nodules due to decrease in cystic size, which we observed that continued for five years of follow up in one of our patients. These will avoid frequent cystic aspiration secondary to recurrence or invasive surgical management.

Radioiodine and Percutaneous Ethanol Injection in the Treatment of Large Toxic Thyroid Nodule: A Long-Term Study

Thyroid ◽  
2000 ◽  
Vol 10 (11) ◽  
pp. 985-989 ◽  
Author(s):  
Matteo Zingrillo ◽  
Massimo Torlontano ◽  
Maria R. Ghiggi ◽  
Vincenzo Frusciante ◽  
Antonio Varraso ◽  
...  
Keyword(s):  
Thyroid Nodule ◽  
Percutaneous Ethanol Injection ◽  
Term Study ◽  
Ethanol Injection ◽  
Long Term Study
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