scholarly journals In Silico Tissue Engineering: A Coupled Agent-Based Finite Element Approach

2019 ◽  
Vol 25 (11) ◽  
pp. 641-654
Author(s):  
Maziyar Keshavarzian ◽  
Clark A. Meyer ◽  
Heather N. Hayenga
2005 ◽  
Vol 2 (1) ◽  
pp. 17-29 ◽  
Author(s):  
Z. Fang ◽  
C. Yan ◽  
W. Sun ◽  
A. Shokoufandeh ◽  
W. Regli

Actual prediction of the effective mechanical properties of tissue scaffolds is very important for tissue engineering applications. Currently common homogenization methods are based on three available approaches: standard mechanics modeling, homogenization theory, and finite element methods. Each of these methods has advantages and limitations. This paper presents comparisons and applications of these approaches for the prediction of the effective properties of a tissue scaffold. Derivations and formulations of mechanics, homogenization, and finite element approach as they relate to tissue engineering are described. The process for the development of a computational algorithm, finite element implementation, and numerical solution for calculating the effective mechanical properties of porous tissue scaffolds are also given. A comparison of the results based upon these different approaches is presented. Parametric analyses using the homogenization approach to study the effects of different scaffold materials and pore shapes on the properties of the scaffold are conducted, and the results of the analyses are also presented.


2007 ◽  
Vol 35 (3) ◽  
pp. 165-182 ◽  
Author(s):  
Maik Brinkmeier ◽  
Udo Nackenhorst ◽  
Heiner Volk

Abstract The sound radiating from rolling tires is the most important source of traffic noise in urban regions. In this contribution a detailed finite element approach for the dynamics of tire/road systems is presented with emphasis on rolling noise prediction. The analysis is split into sequential steps, namely, the nonlinear analysis of the stationary rolling problem within an arbitrary Lagrangian Eulerian framework, and a subsequent analysis of the transient dynamic response due to the excitation caused by road surface roughness. Here, a modal superposition approach is employed using complex eigenvalue analysis. Finally, the sound radiation analysis of the rolling tire/road system is performed.


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