scholarly journals Comparison of Methods for Whole-Organ Decellularization in Tissue Engineering of Bioartificial Organs

2013 ◽  
Vol 19 (3) ◽  
pp. 194-208 ◽  
Author(s):  
Ming He ◽  
Anthony Callanan
Nanomaterials ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. 1861
Author(s):  
Armin Mooranian ◽  
Melissa Jones ◽  
Corina Mihaela Ionescu ◽  
Daniel Walker ◽  
Susbin Raj Wagle ◽  
...  

The utilisation of bioartificial organs is of significant interest to many due to their versatility in treating a wide range of disorders. Microencapsulation has a potentially significant role in such organs. In order to utilise microcapsules, accurate characterisation and analysis is required to assess their properties and suitability. Bioartificial organs or transplantable microdevices must also account for immunogenic considerations, which will be discussed in detail. One of the most characterized cases is the investigation into a bioartificial pancreas, including using microencapsulation of islets or other cells, and will be the focus subject of this review. Overall, this review will discuss the traditional and modern technologies which are necessary for the characterisation of properties for transplantable microdevices or organs, summarizing analysis of the microcapsule itself, cells and finally a working organ. Furthermore, immunogenic considerations of such organs are another important aspect which is addressed within this review. The various techniques, methodologies, advantages, and disadvantages will all be discussed. Hence, the purpose of this review is providing an updated examination of all processes for the analysis of a working, biocompatible artificial organ.


2009 ◽  
Vol 3 (1) ◽  
pp. 9-14
Author(s):  
Gaurav Vasudeva ◽  
Pawah Salil

ABSTRACT Modern dentistry and research will make possible the maintenance of comprehensive oral health by involving the use of nanomaterials, biotechnology including tissue engineering and, ultimately, dental nanorobotics (nanomedicine). Within 10 to 20 years, these devices will allow precisely controlled oral analgesia, dentition replacement therapy using biologically autologous whole replacement teeth manufactured during a single office visit, and rapid nanometer-scale precision restorative dentistry. Tissue engineering is a novel and highly exciting field of research that aims to repair damaged tissues as well as create replacement (bioartificial) organs. A general review of the principles underlying key tissue engineering strategies are described. PRACTICE IMPLICATIONS Tissue engineering will have a considerable effect on dental practice during the next 25 years. The greatest effects will likely be related to the repair and replacement of mineralized tissues, the promotion of oral wound healing and the use of gene transfer adjunctively


2019 ◽  
Vol 43 (6) ◽  
pp. 536-541 ◽  
Author(s):  
Taufiek Konrad Rajab ◽  
Vakhtang Tchantchaleishvili

2000 ◽  
Vol 50 (5) ◽  
pp. 463-463 ◽  
Author(s):  
W. M. Miller ◽  
Madhusudan V. Peshwa

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