scholarly journals Characterization of Total and Active Matrix Metalloproteinases-1, -3, and -13 Synthesized and Secreted by Anterior Cruciate Ligament Fibroblasts in Three-Dimensional Collagen Gels

2014 ◽  
Vol 20 (1-2) ◽  
pp. 171-177 ◽  
Author(s):  
Erik Attia ◽  
Krista Bohnert ◽  
Haydee Brown ◽  
Madhu Bhargava ◽  
Jo A. Hannafin
Keyword(s):  
Anterior Cruciate Ligament ◽  
Matrix Metalloproteinases ◽  
Cruciate Ligament ◽  
Three Dimensional ◽  
Collagen Gels ◽  
Active Matrix ◽  
Anterior Cruciate

scholarly journals Diagnostic performance of 3D TSE MRI versus 2D TSE MRI of the knee at 1.5 T, with prompt arthroscopic correlation, in the detection of meniscal and cruciate ligament tears

2016 ◽  
Vol 49 (2) ◽  
pp. 69-74 ◽  
Author(s):  
Francisco Abaeté Chagas-Neto ◽  
Marcello Henrique Nogueira-Barbosa ◽  
Mário Müller Lorenzato ◽  
Rodrigo Salim ◽  
Maurício Kfuri-Junior ◽  
...  
Keyword(s):  
Anterior Cruciate Ligament ◽  
Diagnostic Performance ◽  
Spin Echo ◽  
Cruciate Ligament ◽  
Three Dimensional ◽  
Meniscal Tears ◽  
Turbo Spin Echo ◽  
Turbo Spin ◽  
Anterior Cruciate ◽  
Cruciate Ligament Tears

Abstract Objective: To compare the diagnostic performance of the three-dimensional turbo spin-echo (3D TSE) magnetic resonance imaging (MRI) technique with the performance of the standard two-dimensional turbo spin-echo (2D TSE) protocol at 1.5 T, in the detection of meniscal and ligament tears. Materials and Methods: Thirty-eight patients were imaged twice, first with a standard multiplanar 2D TSE MR technique, and then with a 3D TSE technique, both in the same 1.5 T MRI scanner. The patients underwent knee arthroscopy within the first three days after the MRI. Using arthroscopy as the reference standard, we determined the diagnostic performance and agreement. Results: For detecting anterior cruciate ligament tears, the 3D TSE and routine 2D TSE techniques showed similar values for sensitivity (93% and 93%, respectively) and specificity (80% and 85%, respectively). For detecting medial meniscal tears, the two techniques also had similar sensitivity (85% and 83%, respectively) and specificity (68% and 71%, respectively). In addition, for detecting lateral meniscal tears, the two techniques had similar sensitivity (58% and 54%, respectively) and specificity (82% and 92%, respectively). There was a substantial to almost perfect intraobserver and interobserver agreement when comparing the readings for both techniques. Conclusion: The 3D TSE technique has a diagnostic performance similar to that of the routine 2D TSE protocol for detecting meniscal and anterior cruciate ligament tears at 1.5 T, with the advantage of faster acquisition.

scholarly journals Characterization of human telomerase reverse transcriptase immortalized anterior cruciate ligament cell lines

2019 ◽  
Vol 42 (6) ◽  
pp. 371-380 ◽  
Author(s):  
Patrick Prager ◽  
Matthias Schieker ◽  
Franz Jakob ◽  
Denitsa Docheva ◽  
Christian Konrads ◽  
...  
Keyword(s):  
Anterior Cruciate Ligament ◽  
Reverse Transcriptase ◽  
Cell Lines ◽  
Cruciate Ligament ◽  
Telomerase Reverse Transcriptase ◽  
Human Telomerase Reverse Transcriptase ◽  
Anterior Cruciate ◽  
Human Telomerase
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