scholarly journals Effective Delivery of Stem Cells Using an Extracellular Matrix Patch Results in Increased Cell Survival and Proliferation and Reduced Scarring in Skin Wound Healing

2013 ◽  
Vol 19 (5-6) ◽  
pp. 738-747 ◽  
Author(s):  
Mai T. Lam ◽  
Allison Nauta ◽  
Nathaniel P. Meyer ◽  
Joseph C. Wu ◽  
Michael T. Longaker
Keyword(s):  
Stem Cells ◽  
Extracellular Matrix ◽  
Wound Healing ◽  
Cell Survival ◽  
Skin Wound ◽  
Skin Wound Healing ◽  
Effective Delivery ◽  
Matrix Patch ◽  
Cell Survival And Proliferation

Prospective application of exosomes derived from adipose‐derived stem cells in skin wound healing: A review

2019 ◽  
Vol 19 (3) ◽  
pp. 574-581 ◽  
Author(s):  
He Qiu ◽  
Shuo Liu ◽  
Kelun Wu ◽  
Rui Zhao ◽  
Lideng Cao ◽  
...  
Keyword(s):  
Stem Cells ◽  
Wound Healing ◽  
Skin Wound ◽  
Adipose Derived Stem Cells ◽  
Skin Wound Healing ◽  
Prospective Application

scholarly journals Epidermal Stem Cells in Skin Wound Healing

2017 ◽  
Vol 6 (9) ◽  
pp. 297-307 ◽  
Author(s):  
Yuanyuan Li ◽  
Jamie Zhang ◽  
Jiping Yue ◽  
Xuewen Gou ◽  
Xiaoyang Wu
Keyword(s):  
Stem Cells ◽  
Wound Healing ◽  
Skin Wound ◽  
Epidermal Stem Cells ◽  
Skin Wound Healing

scholarly journals The Role of Stem Cells During Scarless Skin Wound Healing

2014 ◽  
Vol 3 (4) ◽  
pp. 304-314 ◽  
Author(s):  
Michael Sung-Min Hu ◽  
Robert C. Rennert ◽  
Adrian McArdle ◽  
Michael T. Chung ◽  
Graham G. Walmsley ◽  
...  
Keyword(s):  
Stem Cells ◽  
Wound Healing ◽  
Skin Wound ◽  
Skin Wound Healing

scholarly journals Intradermal injection of human adipose-derived stem cells accelerates skin wound healing in nude mice

2015 ◽  
Vol 6 (1) ◽  
Author(s):  
Jonathan Rodriguez ◽  
Fabien Boucher ◽  
Charlotte Lequeux ◽  
Audrey Josset-Lamaugarny ◽  
Ondine Rouyer ◽  
...  
Keyword(s):  
Stem Cells ◽  
Wound Healing ◽  
Nude Mice ◽  
Skin Wound ◽  
Intradermal Injection ◽  
Adipose Derived Stem Cells ◽  
Skin Wound Healing

scholarly journals Extracellular Matrix-Inspired Growth Factor Delivery Systems for Skin Wound Healing

2015 ◽  
Vol 4 (8) ◽  
pp. 479-489 ◽  
Author(s):  
Priscilla S. Briquez ◽  
Jeffrey A. Hubbell ◽  
Mikaël M. Martino
Keyword(s):  
Extracellular Matrix ◽  
Wound Healing ◽  
Growth Factor ◽  
Delivery Systems ◽  
Skin Wound ◽  
Growth Factor Delivery ◽  
Skin Wound Healing

scholarly journals Toward understanding scarless skin wound healing and pathological scarring

F1000Research ◽  
2019 ◽  
Vol 8 ◽  
pp. 787 ◽  
Author(s):  
Sanna-Maria Karppinen ◽  
Ritva Heljasvaara ◽  
Donald Gullberg ◽  
Kaisa Tasanen ◽  
Taina Pihlajaniemi
Keyword(s):  
Extracellular Matrix ◽  
Wound Healing ◽  
Healing Process ◽  
Cell Types ◽  
Skin Wound ◽  
Skin Wounds ◽  
Medical Problems ◽  
Skin Wound Healing ◽  
Recent Developments ◽  
Acute Wound

The efficient healing of skin wounds is crucial for securing the vital barrier function of the skin, but pathological wound healing and scar formation are major medical problems causing both physiological and psychological challenges for patients. A number of tightly coordinated regenerative responses, including haemostasis, the migration of various cell types into the wound, inflammation, angiogenesis, and the formation of the extracellular matrix, are involved in the healing process. In this article, we summarise the central mechanisms and processes in excessive scarring and acute wound healing, which can lead to the formation of keloids or hypertrophic scars, the two types of fibrotic scars caused by burns or other traumas resulting in significant functional or aesthetic disadvantages. In addition, we discuss recent developments related to the functions of activated fibroblasts, the extracellular matrix and mechanical forces in the wound environment as well as the mechanisms of scarless wound healing. Understanding the different mechanisms of wound healing is pivotal for developing new therapies to prevent the fibrotic scarring of large skin wounds.

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