Use of anin VitroModel of Tissue-Engineered Skin to Investigate the Mechanism of Skin Graft Contraction

2006 ◽  
Vol 12 (11) ◽  
pp. 3119-3133 ◽  
Author(s):  
Caroline A. Harrison ◽  
Fatma Gossiel ◽  
Christopher M. Layton ◽  
Anthony J. Bullock ◽  
Timothy Johnson ◽  
...  
Keyword(s):  
Skin Graft ◽  
Skin Graft Contraction

The Effects of Botulinum Toxin A on the Wound and Skin Graft Contraction

2014 ◽  
Vol 25 (5) ◽  
pp. 1908-1911 ◽  
Author(s):  
Deniz Kucukkaya ◽  
Saime Irkoren ◽  
Selman Ozkan ◽  
Nazan Sivrioglu
Keyword(s):  
Botulinum Toxin ◽  
Skin Graft ◽  
Botulinum Toxin A ◽  
Toxin A ◽  
Skin Graft Contraction

Web space traction device: an effective way for the prevention of web space skin graft contraction

2012 ◽  
Vol 35 (12) ◽  
pp. 873-880
Author(s):  
Harith Abduljabbar Alani ◽  
Ahmed Abdul Razzaq ◽  
Zakaria Y. Arajy
Keyword(s):  
Skin Graft ◽  
Traction Device ◽  
Web Space ◽  
Skin Graft Contraction

The Use of Split Thickness Skin Grafts in the Correction of Apert’s Syndactyly

2001 ◽  
Vol 26 (1) ◽  
pp. 8-10 ◽  
Author(s):  
M. M. AL-QATTAN
Keyword(s):  
Skin Graft ◽  
Joint Contracture ◽  
Skin Grafts ◽  
Thickness Skin ◽  
Constant Feature ◽  
Apert's Syndrome ◽  
Web Space ◽  
Skin Graft Contraction ◽  
The Web

Stiffness of the interphalangeal joints of the fingers is a constant feature of Apert’s syndrome. Because of this stiffness, the author has used split-thickness skin grafts when correcting Apert’s syndactyly, thinking that contraction of such grafts post-operatively would not cause any joint contracture or finger deviation. This paper reports the results of eight patients whose average age at first surgery was 6 months. Separation of all digits was accomplished before the age of 2 years. A dorsal rectangular flap and interposing triangular digital flaps were utilised to create the web space and partially cover the skin defects in the fingers. The remaining digital defects were covered with thin split-thickness skin grafts which took fully in all cases. At final follow-up (1–6 years), the areas covered by skin grafts have reduced in size significantly because of skin graft contraction. However, this did not result joint contracture or digital deviation.

The mechanism of skin graft contraction: An update on current research and potential future therapies

Burns ◽  
2008 ◽  
Vol 34 (2) ◽  
pp. 153-163 ◽  
Author(s):  
Caroline A. Harrison ◽  
Sheila MacNeil
Keyword(s):  
Skin Graft ◽  
Skin Graft Contraction

Use of anin VitroModel of Tissue-Engineered Skin to Investigate the Mechanism of Skin Graft Contraction

2006 ◽  
Vol 0 (0) ◽  
pp. 061004065151003
Author(s):  
Caroline A. Harrison ◽  
Fatma Gossiel ◽  
Christopher M. Layton ◽  
Anthony J. Bullock ◽  
Timothy Johnson ◽  
...  
Keyword(s):  
Skin Graft ◽  
Skin Graft Contraction

Contraction of the composite skin graft and autograft

2002 ◽  
Vol 10 (4) ◽  
pp. 155-157
Author(s):  
Alfredo Gragnani ◽  
Jeffrey R Morgan ◽  
Lydia Masako Ferreira
Keyword(s):  
Experimental Data ◽  
Skin Graft ◽  
Composite Graft ◽  
Skin Grafts ◽  
Athymic Mice ◽  
Transparent Film ◽  
Wound Area ◽  
Burned Patient ◽  
Cultured Keratinocytes ◽  
Skin Graft Contraction

Wound contraction as a result of a delay in grafting or second intention healing in an area that there was no graft take is a serious problem because of the sequela to the burned patient. The objective of the present study was to evaluate the contraction of the cultured keratinocytes and human acellular dermis composite graft by tracing the graft with transparent film after transplantation to the back of athymic mice. The evaluation of the contraction of the composite skin grafts and autografts in relation to the original wound area on the back of the athymic mice demonstrated greater contraction of the grafts after the dressings were removed on the seventh day. The composite skin graft contraction was significantly bigger than the autograft contraction. The experimental data suggested that the contraction appeared after dressing removal, but that the macroscopic aspect of the composite skin graft remained normal with no distortion of the graft or the surrounded murine skin.

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