scholarly journals Inadequate Antibiotic Therapy Results in Higher Recurrence Rate after Drainage of Complicated Peri-Rectal Abscess

2020 ◽  
Vol 21 (10) ◽  
pp. 823-827
Author(s):  
Rohit K. Rasane ◽  
Adrian A. Centeno Coleoglou ◽  
Christopher B. Horn ◽  
Marlon Barboza Torres ◽  
Eden Nohra ◽  
...  
Keyword(s):  
Antibiotic Therapy ◽  
Recurrence Rate ◽  
Inadequate Antibiotic Therapy

scholarly journals The Impact of Healthcare-Associated Infection on Mortality: Failure in Clinical Recognition Is Related with Inadequate Antibiotic Therapy

PLoS ONE ◽  
2013 ◽  
Vol 8 (3) ◽  
pp. e58418 ◽  
Author(s):  
Teresa Cardoso ◽  
Orquídea Ribeiro ◽  
Irene Aragão ◽  
Altamiro Costa-Pereira ◽  
António Sarmento
Keyword(s):  
Antibiotic Therapy ◽  
Healthcare Associated Infection ◽  
Inadequate Antibiotic Therapy ◽  
Healthcare Associated ◽  
The Impact

scholarly journals 1075 PREDICTABILITY OF RECURRENCE RATE OF URINARY TRACT INFECTIONS AND RESPONSE TO ANTIBIOTIC THERAPY BASED ON ANTIBODY COATED BACTERIA TESTING

1978 ◽  
Vol 12 ◽  
pp. 543-543
Author(s):  
Abdollah Iravani ◽  
George A Richard ◽  
Manop Luengnaruemitchai ◽  
Robert L Williams ◽  
Stanford T Shulman
Keyword(s):  
Urinary Tract ◽  
Antibiotic Therapy ◽  
Recurrence Rate ◽  
Urinary Tract Infections ◽  
Tract Infections

Surgical Site Infections: Does Inadequate Antibiotic Therapy Affect Patient Outcomes?

2009 ◽  
Vol 10 (4) ◽  
pp. 323-331 ◽  
Author(s):  
Kathryn J. Eagye ◽  
Aryun Kim ◽  
Somvadee Laohavaleeson ◽  
Joseph L. Kuti ◽  
David P. Nicolau
Keyword(s):  
Antibiotic Therapy ◽  
Patient Outcomes ◽  
Surgical Site Infections ◽  
Inadequate Antibiotic Therapy

Recurrence of Otitis Media after Antibiotic Therapy: Comparison of Cephradine and Amoxycillin

1979 ◽  
Vol 7 (6) ◽  
pp. 546-550 ◽  
Author(s):  
Samuel E McLinn
Keyword(s):  
Side Effects ◽  
Antibiotic Therapy ◽  
Clinical Response ◽  
Otitis Media ◽  
Recurrence Rate ◽  
Treatment Groups

The long-term effectiveness of cephradine and amoxycillin in the treatment of otitis media was evaluated in one hundred children ranging in age from 4 months to 14 years. The immediate clinical response was comparable in both treatment groups, but the recurrence rate during a 12-month follow-up period was considerably lower in the patients treated with cephradine. The incidence of side-effects was similar in the two groups.

scholarly journals Issues beyond resistance: inadequate antibiotic therapy and bacterial hypervirulence

FEMS Microbes ◽  
2020 ◽  
Vol 1 (1) ◽  
Author(s):  
Lee W Goneau ◽  
Johannes Delport ◽  
Luana Langlois ◽  
Susan M Poutanen ◽  
Hassan Razvi ◽  
...  
Keyword(s):  
Antibiotic Therapy ◽  
Clinical Significance ◽  
Clinical Course ◽  
Disease Course ◽  
Course Of Disease ◽  
Inadequate Antibiotic Therapy ◽  
Microbe Interactions ◽  
Persistence Factors ◽  
Selection Of

ABSTRACT The administration of antibiotics while critical for treatment, can be accompanied by potentially severe complications. These include toxicities associated with the drugs themselves, the selection of resistant organisms and depletion of endogenous host microbiota. In addition, antibiotics may be associated with less well-recognized complications arising through changes in the pathogens themselves. Growing evidence suggests that organisms exposed to antibiotics can respond by altering the expression of toxins, invasins and adhesins, as well as biofilm, resistance and persistence factors. The clinical significance of these changes continues to be explored; however, it is possible that treatment with antibiotics may inadvertently precipitate a worsening of the clinical course of disease. Efforts are needed to adjust or augment antibiotic therapy to prevent the transition of pathogens to hypervirulent states. Better understanding the role of antibiotic-microbe interactions and how these can influence disease course is critical given the implications on prescription guidelines and antimicrobial stewardship policies.

Perianal abscess and fistula-in-ano in children – evaluation of treatment’s efficacy. Are we able to avoid the recurrence?

2020 ◽  
Vol 92 (1) ◽  
pp. 1-5
Author(s):  
Katarzyna Bałaż ◽  
Agata Trypens ◽  
Dariusz Polnik ◽  
Katarzyna Pankowska-Woźniak ◽  
Piotr Kaliciński
Keyword(s):  
Antibiotic Therapy ◽  
Recurrence Rate ◽  
Perianal Abscess ◽  
High Recurrence Rate ◽  
Invasive Approach ◽  
Incision And Drainage ◽  
Surgical Interventions ◽  
Fistula In Ano ◽  
Group I ◽  
Group Ii

AIM Perianal abscess and fistula-in-ano are common findings in infants and children. The perianal abscess is usually a manifestation of the fistula-in-ano. Experience of our center indicates a general lack of knowledge of the abscess’s origin therefore it is usually treated by incision and drainage which leads to numerous recurrence. We aimed to present the optimal management of the fistula-in-ano and perianal abscess to lower or even eliminate recurrences. METHOD The retrospective study consisted of 24 infants treated in our center with perianal abscess from 2013 to 2015. The patients were divided into two groups: group I (50%) was primary treated in our center, group II had prior surgical interventions in other hospitals. Fistula-in-ano was intraoperatively identified in all patients (100%) and fistulotomy was performed. RESULTS No recurrence of the perianal abscess or fetal incontinence were observed in any patient. In the group II, the ailment was associated with severe inflammation, some patients underwent an additional surgical intervention such as incision and drainage of the extensive buttock’s abscess; the patients required longer antibiotic therapy and longer hospitalization. CONCLUSION Low-invasive approach (hip-bath, antibiotic therapy, puncture or incision and drainage of the abscess) seems to be tempting due to its simplicity and no need of general anesthesia but it is associated with high recurrence rate. Fistulotomy and fistulectomy, which are slightly more invasive procedures, significantly lower the recurrence rate of fistula-in-ano and perianal abscess.

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