scholarly journals Human Amniotic Fluid Stem Cell Preconditioning Improves Their Regenerative Potential

2012 ◽  
Vol 21 (11) ◽  
pp. 1911-1923 ◽  
Author(s):  
Cinzia Rota ◽  
Barbara Imberti ◽  
Michela Pozzobon ◽  
Martina Piccoli ◽  
Paolo De Coppi ◽  
...  
Keyword(s):  
Stem Cell ◽  
Amniotic Fluid ◽  
Human Amniotic Fluid ◽  
Amniotic Fluid Stem Cell

The human amniotic fluid stem cell secretome exerts cardio-active paracrine potential for myocardial repair and regeneration

Cytotherapy ◽  
2020 ◽  
Vol 22 (5) ◽  
pp. S171
Author(s):  
A. Costa ◽  
C. Balbi ◽  
P.R. Garbati ◽  
K. Lodder ◽  
T. van Herwaarden ◽  
...  
Keyword(s):  
Stem Cell ◽  
Amniotic Fluid ◽  
Myocardial Repair ◽  
Human Amniotic Fluid ◽  
Amniotic Fluid Stem Cell

Exploiting the human amniotic fluid stem cell secretome for myocardial renewal

2020 ◽  
Vol 132 ◽  
pp. 106707
Author(s):  
A. Costa ◽  
C. Balbi ◽  
K. Lodder ◽  
P. Garbati ◽  
T. van Herwaarden ◽  
...  
Keyword(s):  
Stem Cell ◽  
Amniotic Fluid ◽  
Human Amniotic Fluid ◽  
Amniotic Fluid Stem Cell

scholarly journals Tuberin and PRAS40 are anti-apoptotic gatekeepers during early human amniotic fluid stem-cell differentiation

2011 ◽  
Vol 21 (5) ◽  
pp. 1049-1061 ◽  
Author(s):  
Christiane Fuchs ◽  
Margit Rosner ◽  
Helmut Dolznig ◽  
Mario Mikula ◽  
Nina Kramer ◽  
...  
Keyword(s):  
Stem Cell ◽  
Cell Differentiation ◽  
Amniotic Fluid ◽  
Stem Cell Differentiation ◽  
Human Amniotic Fluid ◽  
Amniotic Fluid Stem Cell ◽  
Early Human

scholarly journals Prenatal transplantation of human amniotic fluid stem cell could improve clinical outcome of type III spinal muscular atrophy in mice

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Steven W. Shaw ◽  
Shao-Yu Peng ◽  
Ching-Chung Liang ◽  
Tzu-Yi Lin ◽  
Po-Jen Cheng ◽  
...  
Keyword(s):  
Stem Cell ◽  
Amniotic Fluid ◽  
Spinal Muscular Atrophy ◽  
Motor Function ◽  
Time Window ◽  
Therapeutic Potential ◽  
Muscular Atrophy ◽  
Single Gene ◽  
Human Amniotic Fluid ◽  
Amniotic Fluid Stem Cell

AbstractSpinal muscular atrophy (SMA) is a single gene disorder affecting motor function in uterus. Amniotic fluid is an alternative source of stem cell to ameliorate SMA. Therefore, this study aims to examine the therapeutic potential of Human amniotic fluid stem cell (hAFSC) for SMA. Our SMA model mice were generated by deletion of exon 7 of Smn gene and knock-in of human SMN2. A total of 16 SMA model mice were injected with 1 × 105 hAFSC in uterus, and the other 16 mice served as the negative control. Motor function was analyzed by three behavioral tests. Engraftment of hAFSC in organs were assessed by flow cytometry and RNA scope. Frequency of myocytes, neurons and innervated receptors were estimated by staining. With hAFSC transplantation, 15 fetuses survived (93.75% survival) and showed better performance in all motor function tests. Higher engraftment frequency were observed in muscle and liver. Besides, the muscle with hAFSC transplantation expressed much laminin α and PAX-7. Significantly higher frequency of myocytes, neurons and innervated receptors were observed. In our study, hAFSC engrafted on neuromuscular organs and improved cellular and behavioral outcomes of SMA model mice. This fetal therapy could preserve the time window and treat in the uterus.

BMP15 Gene Is Activated During Human Amniotic Fluid Stem Cell Differentiation into Oocyte-Like Cells

2012 ◽  
Vol 31 (7) ◽  
pp. 1198-1204 ◽  
Author(s):  
Xiang Cheng ◽  
Shuai Chen ◽  
Xiaoli Yu ◽  
Pengsheng Zheng ◽  
Huayan Wang
Keyword(s):  
Stem Cell ◽  
Cell Differentiation ◽  
Amniotic Fluid ◽  
Stem Cell Differentiation ◽  
Human Amniotic Fluid ◽  
Amniotic Fluid Stem Cell

The human amniotic fluid stem cell secretome as new paracrine source to unlock endogenous cardiac regeneration

2018 ◽  
Vol 103-105 ◽  
pp. 47-48
Author(s):  
C. Balbi ◽  
L. Barile ◽  
S. Moimas ◽  
F. Moccia ◽  
A. Smits ◽  
...  
Keyword(s):  
Stem Cell ◽  
Amniotic Fluid ◽  
Cardiac Regeneration ◽  
Human Amniotic Fluid ◽  
Amniotic Fluid Stem Cell

scholarly journals Vascular Endothelial Growth Factor Up-regulation in Human Amniotic Fluid Stem Cell Enhances Nephroprotection After Ischemia-Reperfusion Injury in the Rat

2017 ◽  
Vol 45 (1) ◽  
pp. e86-e96 ◽  
Author(s):  
Marina Gabriela Monteiro Carvalho Mori da Cunha ◽  
Silvia Zia ◽  
Diego Vilibaldo Beckmann ◽  
Marianne Sylvia Carlon ◽  
Fanny Oliveira Arcolino ◽  
...  
Keyword(s):  
Vascular Endothelial Growth Factor ◽  
Stem Cell ◽  
Growth Factor ◽  
Amniotic Fluid ◽  
Ischemia Reperfusion Injury ◽  
Ischemia Reperfusion ◽  
Vascular Endothelial ◽  
Human Amniotic Fluid ◽  
Amniotic Fluid Stem Cell ◽  
Endothelial Growth Factor
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