Diagnosis and Treatment of Eosinophilic Gastrointestinal Disorders

2010 ◽  
Vol 23 (4) ◽  
pp. 237-242 ◽  
Author(s):  
Carla M. Davis
Keyword(s):  
Diagnosis And Treatment ◽  
Gastrointestinal Disorders ◽  
Eosinophilic Gastrointestinal Disorders

scholarly journals Eosinophilic Gastrointestinal Diseases: Review and Update

2012 ◽  
Vol 2012 ◽  
pp. 1-8 ◽  
Author(s):  
Mahreema Jawairia ◽  
Ghulamullah Shahzad ◽  
Paul Mustacchia
Keyword(s):  
Gastrointestinal Tract ◽  
Clinical Features ◽  
Gastrointestinal Symptoms ◽  
Gastrointestinal Diseases ◽  
Gastrointestinal Disorders ◽  
Diverse Group ◽  
Intestinal Diseases ◽  
Gastrointestinal Inflammation ◽  
Eosinophilic Gastrointestinal Disorders

Eosinophilic gastrointestinal disorders (EGIDs) are a progressively more frequent diverse group of intestinal diseases. The intention of this paper is to present the newest developments in the care of patients with EGIDs and to sum up a rising literature defining the clinical features and mechanistic elements of eosinophils and their intricate associations with the gastrointestinal tract. Clinicians ought to stay sensitive to EGIDs as a diagnostic likelihood for patients with general gastrointestinal symptoms. Further research is warranted to establish various methods leading to dysfunction coupled with eosinophilic gastrointestinal inflammation.

Eosinophilic gastroenteritis: a case report and a review of eosinophilic gastrointestinal disorders

2013 ◽  
pp. 166-171 ◽  
Author(s):  
Chiara Benatti ◽  
Carla Sacchetti ◽  
Antonio Pedrazzi ◽  
Claudio Gollini ◽  
Federica Vecchi ◽  
...  
Keyword(s):  
Gastrointestinal Tract ◽  
White Cell Count ◽  
Clinical History ◽  
Eosinophilic Gastroenteritis ◽  
Endoscopic Biopsy ◽  
Gastrointestinal Disorders ◽  
Abdominal Ultrasonography ◽  
Benign Condition ◽  
Peritoneal Effusion ◽  
Eosinophilic Gastrointestinal Disorders

Background: Despite its uncommon occurrence, eosinophilic gastroenteritis is one of the most important primary eosinophilic gastrointestinal disorders. These are defined as disorders that selectively affect the gastrointestinal tract with eosinophil-rich inflammation in the absence of known causes for eosinophilia. The disorders include eosinophilic esophagitis, eosinophilic gastritis, eosinophilic gastroenteritis, eosinophilic enteritis and eosinophilic colitis. Aim of the study: This review focuses on the epidemiology, pathophysiology, clinical features and treatment of primary eosinophilic gastrointestinal disorders with particular attention to primary eosinophilic gastroenteritis. Clinical case: We report a case of a 32-years-old woman that was admitted to our Hospital complaining of abdominal pain, ascites and diarrhea. Laboratory investigations showed a white cell count of 15.1 thousands/mm3 with eosinophilia; other laboratory studies were within the normal limits. Abdominal ultrasonography demonstrated peritoneal effusion and cytological analysis revealed a prevalence of eosinophils in the ascites. The multiple endoscopic biopsies were normal. However, the clinical history, and the laboratory, radiological and endoscopic findings gave a firm diagnosis of the serosal form of primary eosinophilic gastroenteritis. Discussion: This is a rare, benign condition, pathologically characterized by an important eosinophilic infiltration of the wall of the digestive tract and presents a constellation of symptoms that are related to the degree and area of the gastrointestinal tract affected. Primary eosinophilic gastroenteritis encompasses multiple disease entities subcategorized into three types on the basis of the level of histologic involvement: mucosal, muscolaris and serosal forms. Every layer of the gastrointestinal tract can be involved, so that endoscopic biopsy can be normal in patients with the muscolaris subtype, serosal subtype, or both.

scholarly journals Treatment Adherence in Pediatric Eosinophilic Gastrointestinal Disorders

2011 ◽  
Vol 37 (5) ◽  
pp. 533-542 ◽  
Author(s):  
K. A. Hommel ◽  
J. P. Franciosi ◽  
E. A. Hente ◽  
A. Ahrens ◽  
M. E. Rothenberg
Keyword(s):  
Treatment Adherence ◽  
Gastrointestinal Disorders ◽  
Eosinophilic Gastrointestinal Disorders

scholarly journals Endoscopic findings of gastric lesions in patients with eosinophilic gastrointestinal disorders

2020 ◽  
Vol 08 (12) ◽  
pp. E1817-E1825
Author(s):  
Yasuhiro Fujiwara ◽  
Kojiro Tanoue ◽  
Akira Higashimori ◽  
Yu Nishida ◽  
Masatsugu Maruyama ◽  
...  
Keyword(s):  
Eosinophilic Esophagitis ◽  
Submucosal Tumor ◽  
Eosinophilic Gastroenteritis ◽  
Gastrointestinal Disorders ◽  
Gastric Lesions ◽  
Pyloric Ring ◽  
Eosinophilic Colitis ◽  
Endoscopic Findings ◽  
Eosinophilic Gastritis ◽  
Eosinophilic Gastrointestinal Disorders

Abstract Background and study aims Eosinophilic gastrointestinal disorders are classified into eosinophilic esophagitis, eosinophilic gastritis, eosinophilic gastroenteritis, and eosinophilic colitis according to the site of eosinophilic infiltration. Although well established in eosinophilic esophagitis, endoscopic findings in eosinophilic gastritis and eosinophilic gastroenteritis with regard to gastric lesions have not been clearly described. The aim of this study was to identify endoscopic findings of gastric lesions associated with eosinophilic gastrointestinal disorders. Patients and methods Out of 278 patients with eosinophilic gastrointestinal disorders, 18 had eosinophilic gastritis or eosinophilic gastroenteritis confirmed by biopsy; their endoscopic images were analyzed retrospectively. The association between endoscopic findings and number of eosinophils in the gastric mucosa was investigated. Results Erythema was most frequently observed (72 %), followed by ulcers (39 %), discoloration (33 %), erosions (28 %), nodularity (28 %), and polyps (28 %). There were several unique endoscopic findings such as submucosal tumor-like deep large ulcers in three patients, antral Penthorum-like appearances (small nodules radially lined toward the pyloric ring) in three patients, “muskmelon-like appearances” (discolored mucosa-composed mesh pattern) in three patients, multiple white granular elevations in two patients, cracks (appearance of furrows similar to those in eosinophilic esophagitis) in five patients, and antral rings in one patient. No significant association was observed between endoscopic findings and number of gastric eosinophils. Conclusions Several unique endoscopic findings of gastric lesions were observed in patients with eosinophilic gastritis or eosinophilic gastroenteritis. Submucosal tumor-like ulcers, antral Penthorum-like appearances, muskmelon-like appearances, and cracks might be associated with eosinophilic gastrointestinal disorders.

scholarly journals Mo1133 – High Patient-Reported Disease Burden for Eosinophilic Gastrointestinal Disorders

2019 ◽  
Vol 156 (6) ◽  
pp. S-717
Author(s):  
Elizabeth T. Jensen ◽  
Juan P. Abonia ◽  
Seema S. Aceves ◽  
Peter A. Bonis ◽  
Kimberly Bray ◽  
...  
Keyword(s):  
Disease Burden ◽  
Gastrointestinal Disorders ◽  
Patient Reported ◽  
Eosinophilic Gastrointestinal Disorders
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