White Matter Changes Caused by Mild Traumatic Brain Injury in Mice Evaluated Using Neurite Orientation Dispersion and Density Imaging

2020 ◽  
Vol 37 (16) ◽  
pp. 1818-1828
Author(s):  
Lisa M. Gazdzinski ◽  
Miranda Mellerup ◽  
Tong Wang ◽  
Seyed Amir Ali Adel ◽  
Jason P. Lerch ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
White Matter ◽  
Mild Traumatic Brain Injury ◽  
White Matter Changes

Vestibular, balance, microvascular and white matter neuroimaging characteristics of blast injuries and mild traumatic brain injury: Four case reports

Brain Injury ◽  
2016 ◽  
Vol 30 (12) ◽  
pp. 1501-1514 ◽  
Author(s):  
Ramtilak Gattu ◽  
Faith W. Akin ◽  
Anthony T. Cacace ◽  
Courtney D. Hall ◽  
Owen D. Murnane ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
White Matter ◽  
Mild Traumatic Brain Injury ◽  
Case Reports ◽  
Blast Injuries

scholarly journals Acute mild traumatic brain injury is not associated with white matter change on diffusion tensor imaging

Brain ◽  
2014 ◽  
Vol 137 (7) ◽  
pp. 1876-1882 ◽  
Author(s):  
Tero Ilvesmäki ◽  
Teemu M. Luoto ◽  
Ullamari Hakulinen ◽  
Antti Brander ◽  
Pertti Ryymin ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Diffusion Tensor Imaging ◽  
Brain Injury ◽  
White Matter ◽  
Mild Traumatic Brain Injury ◽  
Diffusion Tensor ◽  
White Matter Change

scholarly journals Acute White Matter Tract Damage after Frontal Mild Traumatic Brain Injury

2017 ◽  
Vol 34 (2) ◽  
pp. 291-299 ◽  
Author(s):  
Juan J. Herrera ◽  
Kurt Bockhorst ◽  
Shakuntala Kondraganti ◽  
Laura Stertz ◽  
João Quevedo ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
White Matter ◽  
Mild Traumatic Brain Injury ◽  
White Matter Tract ◽  
Tract Damage

scholarly journals Structural brain connectivity predicts acute pain after mild traumatic brain injury

2021 ◽  
Author(s):  
Paulo Branco ◽  
Noam Bosak ◽  
Jannis Bielefeld ◽  
Olivia Cong ◽  
Yelena Granovsky ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
White Matter ◽  
Mild Traumatic Brain Injury ◽  
Acute Pain ◽  
Pain Perception ◽  
Strong Predictor ◽  
Pain Modulation ◽  
Acute Injury ◽  
Post Injury

Mild traumatic brain injury, mTBI, is a leading cause of disability worldwide, with acute pain manifesting as one of its most debilitating symptoms. Understanding acute post-injury pain is important since it is a strong predictor of long-term outcomes. In this study, we imaged the brains of 172 patients with mTBI, following a motorized vehicle collision and used a machine learning approach to extract white matter structural and resting state fMRI functional connectivity measures to predict acute pain. Stronger white matter tracts within the sensorimotor, thalamic-cortical, and default-mode systems predicted 20% of the variance in pain severity within 72 hours of the injury. This result generalized in two independent groups: 39 mTBI patients and 13 mTBI patients without whiplash symptoms. White matter measures collected at 6-months after the collision still predicted mTBI pain at that timepoint (n = 36). These white-matter connections were associated with two nociceptive psychophysical outcomes tested at a remote body site – namely conditioned pain modulation and magnitude of suprathreshold pain–, and with pain sensitivity questionnaire scores. Our validated findings demonstrate a stable white-matter network, the properties of which determine a significant amount of pain experienced after acute injury, pinpointing a circuitry engaged in the transformation and amplification of nociceptive inputs to pain perception.

Loss of Consciousness Is Related to White Matter Injury in Mild Traumatic Brain Injury

2016 ◽  
Vol 33 (22) ◽  
pp. 2000-2010 ◽  
Author(s):  
Elisabeth A. Wilde ◽  
Xiaoqi Li ◽  
Jill V. Hunter ◽  
Ponnada A. Narayana ◽  
Khader Hasan ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
White Matter ◽  
Mild Traumatic Brain Injury ◽  
White Matter Injury ◽  
Loss Of Consciousness

scholarly journals Chronic White Matter Degeneration, but No Tau Pathology at One-Year Post-Repetitive Mild Traumatic Brain Injury in a Tau Transgenic Model

2019 ◽  
Vol 36 (4) ◽  
pp. 576-588 ◽  
Author(s):  
Benoit Mouzon ◽  
Corbin Bachmeier ◽  
Joseph Ojo ◽  
Christopher Acker ◽  
Scott Ferguson ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
White Matter ◽  
Mild Traumatic Brain Injury ◽  
Tau Pathology ◽  
Transgenic Model ◽  
White Matter Degeneration ◽  
One Year
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