High-Definition Transcranial Direct Current Stimulation to Improve Verbal Retrieval Deficits in Chronic Traumatic Brain Injury

2020 ◽  
Vol 37 (1) ◽  
pp. 170-177 ◽  
Author(s):  
Michael A. Motes ◽  
Jeffrey S. Spence ◽  
Kylee Yeatman ◽  
Penelope M. Jones ◽  
Morgan Lutrell ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Direct Current ◽  
Transcranial Direct Current Stimulation ◽  
High Definition ◽  
Direct Current Stimulation

scholarly journals Case Report: Improving Verbal Retrieval Deficits With High Definition Transcranial Direct Current Stimulation Targeting the Pre-Supplementary Motor Area in a Patient With Chronic Traumatic Brain Injury

2021 ◽  
Vol 12 ◽  
Author(s):  
Hsueh-Sheng Chiang ◽  
Scott Shakal ◽  
Sven Vanneste ◽  
Michael Kraut ◽  
John Hart
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Direct Current ◽  
Transcranial Direct Current Stimulation ◽  
Supplementary Motor Area ◽  
Event Related Potentials ◽  
Motor Area ◽  
High Definition ◽  
Direct Current Stimulation ◽  
Related Potentials

We report a patient who has cognitive sequalae including verbal retrieval deficits after severe traumatic brain injury (TBI). The cortico-caudate-thalamic circuit involving the pre-Supplementary Motor Area (pre-SMA) has been proposed to underlie verbal retrieval functions. We hypothesized that High Definition-transcranial Direct Current Stimulation (HD-tDCS) targeting the pre-SMA would selectively modulate this circuit to remediate verbal retrieval deficits. After the patient underwent 10 sessions of 20 min of 1 mA HD-tDCS targeting the pre-SMA, we documented significant improvements for verbal fluency and naming, and for working memory and executive function tasks that involve the frontal lobes. The effects persisted for up to 14 weeks after completion of HD-tDCS treatment. We also demonstrated normalization of the event-related potentials suggesting modulation of the underlying neural circuit. Our study implicates that region-specific non-invasive brain stimulation, such as HD-tDCS, serves as a potential individualized therapeutic tool to treat cognitive deficits by inducing longer-lasting neuroplasticity even in the chronic phase of TBI.

scholarly journals Transcranial Direct Current Stimulation as a Treatment Tool for Mild Traumatic Brain Injury

2021 ◽  
Vol 11 (6) ◽  
pp. 806
Author(s):  
Thorsten Rudroff ◽  
Craig D. Workman
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Mild Traumatic Brain Injury ◽  
Direct Current ◽  
Transcranial Direct Current Stimulation ◽  
Therapeutic Potential ◽  
Repetitive Transcranial Magnetic Stimulation ◽  
Motor Impairment ◽  
Direct Current Stimulation ◽  
Main Technique

Mild traumatic brain injury (mTBI) has been defined as a transient (<24 h) condition of confusion and/or loss of consciousness for less than 30 min after brain injury and can result in short- and long-term motor and cognitive impairments. Recent studies have documented the therapeutic potential of non-invasive neuromodulation techniques for the enhancement of cognitive and motor function in mTBI. Alongside repetitive transcranial magnetic stimulation (rTMS), the main technique used for this purpose is transcranial direct current stimulation (tDCS). The focus of this review was to provide a detailed, comprehensive (i.e., both cognitive and motor impairment) overview of the literature regarding therapeutic tDCS paradigms after mTBI. A publication search of the PubMed, Scopus, CINAHL, and PsycINFO databases was performed to identify records that applied tDCS in mTBI. The publication search yielded 14,422 records from all of the databases, however, only three met the inclusion criteria and were included in the final review. Based on the review, there is limited evidence of tDCS improving cognitive and motor performance. Surprisingly, there were only three studies that used tDCS in mTBI, which highlights an urgent need for more research to provide additional insights into ideal therapeutic brain targets and optimized stimulation parameters.

scholarly journals Cathodal Transcranial Direct-Current Stimulation Selectively Decreases Impulsivity after Traumatic Brain Injury in Rats

2019 ◽  
Vol 36 (19) ◽  
pp. 2827-2830 ◽  
Author(s):  
Kris M. Martens ◽  
Kristen M. Pechacek ◽  
Cassandra G. Modrak ◽  
Virginia J. Milleson ◽  
Binxing Zhu ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Direct Current ◽  
Transcranial Direct Current Stimulation ◽  
Direct Current Stimulation
Sign in / Sign up

Export Citation Format

Share Document